OPIS promotes compassionate governance and systemic change, with the goal of preventing and alleviating the intense suffering of all sentient beings. In 2025 we released a wide-ranging publication titled Compassionate Governance: A Strategic Guide to Preventing and Alleviating Global Suffering that pulls together wisdom and essential insights from several fields of expertise, offering recommendations for governance, international cooperation and policymaking.
We also promote effective, evidence-based solutions to specific causes of suffering, including access to effective pain relief. We co-organized a national conference in Burkina Faso on establishing a national palliative care program and, through a partnership we established, successfully advocated for Canada to grant access to psilocybin for the first time to a patient with excruciating cluster headaches. We are also promoting the establishment of suffering metrics in health economics, and concern for suffering prevention within AI safety.
Read more here: https://www.preventsuffering.org/
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