ClusterFree
The world's most painful condition demands urgent action. Help us accelerate access to effective treatments for cluster headaches.
About cluster headache
Cluster headache ("suicide headache") is often considered the most painful medical condition. Patients rate it as significantly more painful than childbirth, kidney stones, gunshot wounds, and bone fractures. Standard painkillers don't help.
Even in wealthy nations with advanced healthcare, hundreds of thousands still experience torture-like suffering every year. About 50% of all patients have contemplated suicide. At the same time, global funding for cluster headache is virtually nonexistent. This crisis cannot go on any longer.
Psychedelics save lives
Psychedelics like psilocybin, LSD, and DMT have shown promise in treating cluster headache pain, in some cases with 70–80% of surveyed users reporting significant relief. Some patients even achieve complete remission.
Often, low, sub-hallucinogenic doses are more than enough to prevent clusters or stop attacks acutely. Patients could self-medicate safely and with minimal side effects.
However, only a tiny minority of patients have access to these life-saving treatments. Given the severity of the pain, the situation is analogous to refusing anesthesia to patients during surgery. This is absolutely unacceptable.
We need your help to accelerate access to effective treatments.
Fundraisers
Official fundraiser
End of Year Fundraiser 2025
Your generous donation helps us tackle one of the most urgent health crises of our time. We have ambitious plans, and we rely on donations to make these plans a reality. ClusterFree launched only a few months ago, but we are excited about the progress we've made so far with a small team and a shoestring budget. Among others, we: Launched our open letters , which have been signed by people like Prof. Peter Singer , Dr. Christopher Gottschalk , Scott Alexander , and many more. Started an official collaboration with Clusterbusters . Gained the support of a member of a US state legislature. Started conversations with CH advocates in multiple countries (most recently India, Denmark, and New Zealand). Are engaging with entrepreneurs and philanthropists interested in bringing DMT to market. Developed a preliminary idea for a new, legal abortive treatment that could be highly effective (potentially also for migraines). Started developing phenomenology-based, patient-centric surveys to test various hypothesis for the underlying mechanism of action that psychedelics exert on this condition. Donations at this early stage would help us hire a second teammate to accelerate our efforts. We believe ClusterFree is a great donation opportunity for people who care about relieving the most intense human suffering today. Cluster headaches represent a major health crisis even in developing countries, and we are far from having effective treatments widely available. Help us change that. -- "Your cluster headache work is superb and admirable - I signed with pleasure." - Robert Lawrence Kuhn "I appreciate your work on this important issue." - Prof. Peter Singer "clusterfree.org is really well put together, with the most important info easily accessed and well focused IMO - a great, appreciated resource!" - Clusterbusters forum user
- Raised
- $107,636
- Goal
- $150,000
24 supporters
DonateDonors
Tawsif Ahmed To the fundraiser: End of Year Fundraiser 20251Take invisible suffering seriously so you can have your invisible suffering taken seriously when you have it!!
Daniel Phillips To the fundraiser: End of Year Fundraiser 20251Possibly the most important and effective suffering-reduction intervention available to humanity right now.
Christoph Ströck To the fundraiser: End of Year Fundraiser 20251Bodhisattvic energy flowing toward purification and clarity, right here, right now.
Thijs Jacobs To the fundraiser: End of Year Fundraiser 20251Very important cause! Happy to donate my End of Year donations to them.
Camille Berger To the fundraiser: End of Year Fundraiser 20251This a common, yet easy-to-solve moral tragedy.
Oleksii Bykhun To the fundraiser: End of Year Fundraiser 20251Great team working on important problem!