QURI's team can deliver, and their current projects are promising (see "What kinds of things might QURI do in the next 10 years?" here: https://quantifieduncertainty.org/2cb83aa3c1f54066b7f0e21446ec96ef).

Rethink Priorities does valuable research related to the effective altruism community and some of the most pressing issues facing humanity: https://rethinkpriorities.org/research

RP is doing great work. Thanks, William, for letting me know about the match!

The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

Evidence Action scales evidence-based and cost-effective programs to reduce the burden of poverty. 

Our organization was founded in 2013 to address a big gap in the fight against global poverty--many of the most promising interventions are either implemented at a very small scale, or not at all. We set out to address this gap by building programs that would scale evidence-based and cost-effective interventions, leading to significant improvements in quality of life for hundreds of millions of people. 

Our model worked. In less than a decade, our two flagship programs, the Deworm the World Initiative and Dispensers for Safe Water, have grown to measurably impact over 280 million people each year. This success is achieved through the dedication and talent of our staff, the hard work of our partners, and the commitment of our supporters.

By 2024, we seek to double our impact. We are strengthening and expanding our existing programs, and working to identify a new generation of evidence-based and cost-effective interventions that we can scale to reach millions more. 

We currently operate three programs:

Dispensers for Safe Water 

Dispensers for Safe Water program delivers free and reliable access to safe water for 4 million people in rural Kenya, Uganda, and Malawi.
In rural parts of low-income countries, most water sources are untreated, meaning that water is not safe to drink directly from the source. Our uniquely-engineered chlorine dispensers are installed next to commonly-used water sources, enabling people to treat their water using a safe and pre-measured dose of chlorine. The chlorine stays active for 2-3 days, ensuring water doesn’t get recontaminated even when stored at home. Adding diluted chlorine to water is a WHO-endorsed approach to improving water quality. 
Dispensers for Safe Water is a cost-effective solution - just over $1.00 delivers safe water access to one person for an entire year. In 2019, our program averted over 380,000 cases of diarrhea among children, one of the main causes of childhood mortality in the countries where we operate.

Deworm the World Initiative

Deworm the World Initiative helps governments launch, scale, and sustain school-based deworming programs.

Over 868 million children globally are at risk of contracting parasitic worm infections. If left untreated, infections can lead to anemia, malnourishment, and impaired mental and physical development—ultimately affecting children’s educational outcomes and income as adults.Our program brings free treatment to children at their schools instead of placing the burden on the families to obtain it. We partner with governments to regularly treat all at-risk children in places where at least 20% are infected with worms, as recommended by the World Health Organization.  

Rigorous research shows that deworming leads to significant improvements to children’s health, education, and long-term wellbeing. In 2019, we helped governments treat over 280 million children in India, Kenya, Nigeria, Ethiopia, and Pakistan for less than US 50 cents per treatment.

Accelerator:  
 
Evidence Action Accelerator is our engine for new program development that selects, optimizes, and scales interventions with the highest potential to measurably improve the lives of millions of people in the world’s poorest places.  

Each intervention considered by the Accelerator must undergo a multi-stage process of program development, taking it from an evidence-based concept to a fully-developed solution that can be replicated in multiple geographies. We look for three critical aspects during the assessment process: rigorous evidence, cost-effectiveness, and potential for scale. 

We are currently accelerating two promising health solutions: working with the Liberian government to detect and treat maternal syphilis, with the aim of preventing thousands of child deaths and disabilities each year; and supporting the Indian government to improve the distribution of iron and folic acid supplementation to millions of children and adolescents —treating iron deficiency anemia, one of the main causes of disability in the country.





Evidence Action

We provide cash incentives for childhood vaccinations. It’s one of the most cost-effective ways known to save lives.


New Incentives’ mission is to save lives in a way that does the **most good per dollar**.
Guided by evidence, we provide cash incentives to increase childhood vaccination rates.

- We [raise awareness](https://www.newincentives.org/blog-posts/awareness-activities) about the benefits of childhood vaccinations.
- We [provide cash incentives](https://www.newincentives.org/blog-posts/a-day-in-the-life-abubakar-aliyu-field-officer) at government clinics after children receive vaccinations.
- We [help improve the vaccine supply chain](https://www.newincentives.org/blog-posts/supporting-government-partners-with-vaccine-supply-efforts) to ensure enough vaccines are available at clinics.

Together, these efforts are proven to double vaccination rates and save lives.
Learn more about the [randomized controlled trial](https://www.newincentives.org/rct-results).

As of March 2024, New Incentives has reached more the 3 million infants in northern Nigeria.

New Incentives

A new initiative to advance forecasting and epistemics for the aim of improving the long term future of humanity.

We research systematic practices to specify and estimate the most important parameters for the most important or scalable decisions. Research areas include forecasting, epistemics, evaluations, ontology, and estimation. We emphasize technological solutions that can heavily scale in the next 5 to 30 years.

We believe that humanity’s success in the next few hundred years will lie intensely on its ability to coordinate and make good decisions. If important governmental and philanthropic bodies become significantly more effective, this will make society far more resilient to many kinds of challenges ahead.

Quantified Uncertainty Research Institute

The Centre for Effective Altruism helps to grow and support the effective altruism community.

Effective altruism is about using evidence and reason to figure out how to benefit others as much as possible, and taking action on that basis.

The Centre for Effective Altruism (CEA) is a charity dedicated to building and nurturing a global community of people who are thinking carefully about the world’s biggest problems and taking impactful action to solve them.

We hope that this community can help to build a radically better world: by connecting students and young professionals with relevant experts, we can help them consider their values and find an effective way to contribute that is a good fit for their skills and inclinations.

Centre for Effective Altruism USA

One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

We are a think tank dedicated to figuring out the best ways to make the world a better place.

Rethink Priorities is a research organization that conducts critical research to inform policymakers and major foundations about how to best help people and nonhuman animals in both the present and the long-term future.

Our research spans everything from animal welfare to the threat of nuclear war. We explore neglected but promising areas to improve the world and try to further build the community of researchers working on understanding how to do this most effectively.

If you'd like to support one of our fiscally sponsored projects (e.g. Epoch), you can give via Every.org, and let us know how to allocate your gift at info@rethinkpriorities.org.

Rethink Priorities

Our research-based matching system motivates people to donate to highly effective charities at givingmultiplier.org.

Giving Multiplier is a Harvard University research project that matches donations to any charity of your choice and promotes the world's most effective charities.

To make a donation that gets matched, go to http://givingmultiplier.org. To become a matching funder, go to http://givingmultiplier.org/matching. (If you donate on this page here, your donation will also go into our matching system.)

Giving Multiplier

Helen Keller, our co-founder, envisioned a world without barriers to human potential. We are continuing her work.


Helen Keller, our co-founder, envisioned a world without barriers to human potential. Guided by her fierce optimism, we have been working on the front lines of health and well-being for more than 100 years. We deliver life-changing health care to vulnerable families in places where the need is great, but access is limited. Our proven, science-based programs empower people to create opportunities in their own lives.


Helen Keller International

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.

GiveWell

AYubnnStGbcU9CeeHevoKfWFfHSV2AwooDDxbZyyBMI=

Monthly donations help nonprofits focus on mission and long-term impact, not fundraising. Cancel anytime.

N6J6uC2BFpY1DBCCNGARPn6U5PWj+hjtybLRiPtieQE=

P4tcjBv99m+mR1oLlHA7veVssOWH2cJ8v/umjSkV7/c=

ipacWjgvkUpq55wyZUwsN4Qjjl7hLlH+eEjYOaQHYFw=

HMbe47+AneGCvW/Xo3JKBD0CoNn+J5g7nYakke86o7I=

QNW+H2PwVn8vv9e5Iz1yCCrYO7y4m9mceodAr9ZQuGo=

XD7WW8JsE2Wq5zNvldYo02kE/9XhuTnMMRIiGDtJ/gw=

Xzooxu7EFYOfep+MPJko33CDGhIpi48EHFdc8PC0QKQ=

q14o0EONZSuc0HViRAdjPcEpjceygaKWHZon938heU0=

Instructions to get up to $300 matched: https://forum.effectivealtruism.org/posts/oMBKeyx7ir8Jnbenz/make-a-usd50-donation-into-usd100-6x