I’m sponsoring Zig because I believe in what the team is building — and how they’re building it.

There’s a rare discipline in choosing not to rush. In prioritizing quality, long-term design, and taste over immediate adoption. The async I/O work is a perfect example of that patience.

I admire the ambition to improve core infrastructure like LLVM, and the pragmatic commitment to first-class C interop.

Zig has made low-level programming click for me in a new way. It strips away unnecessary abstraction while still making very complex systems approachable. I’ve learned more from writing Zig than from almost any other tool.

And honestly — it’s the language I enjoy writing the most.

Open source software powers the world - and the people building, maintaining, and governing FOSS projects deserve better support, fiscal and otherwise.  As a 27 year volunteer at the ASF, I'm helping out financially too at the Open Source Endowment.

Thanks to the ARC Prize Foundation. They are doing great work, Thanks to them for their part in keeping AI research honest and enabling AGI/ASI

Extropic is happy to support the ARC Prize Foundation

This cause is near and dear to my heart as I spent 17 years at Follett Software - the preeminent library software organization in K-12 in the USA and globally. Onward and upward!

This is such an important project that two missionaries like yourselves could spend your lives and their three children's lives to show the path the Lord has chosen for all of you.
You are bringing a sustainable way of life back to the fishermen in the Philippines.
God Bless you all for your dedication and service to the Lord and to the economically depressed population there.
You all are truly doing the Lord's work.  God Bless the Martins!
Darla and Andy

The only fully and easily modular cross platform open source game engine that gives you incredible levels of parallelization performance for free.

Great language. Great people working on it. Worth supporting. 

Aubrey and his teams have a history of making biorejuvenation breakthroughs that lay the groundwork for future anti-aging therapies that will someday save billions of lives. They tackle the intractable bits of aging, bits that are too speculative or longterm or unprofitable for venture capital. I’m proud to support LEVF and Aubrey and their work to defeat aging.

Fighting diseases of old age is one of the most important things there is.

Zig is a general-purpose programming language and toolchain for maintaining robust, optimal, and reusable software.

The Zig Software Foundation is a non-profit corporation founded in 2020 by Andrew Kelley, the creator of Zig, with the goal of supporting the development of the language. Currently, the ZSF is able to offer paid work at competitive rates to a small number of core contributors. We hope to be able to extend this offer to more core contributors in the future.

Zig Software Foundation Inc

Open Source Endowment

ARC Prize Foundation builds and deployed AI benchmarks that measure and guide research

ARC Prize launched in 2024 as an experiment to promote the relatively obscure, but important, ARC-AGI benchmark. Now, after our OpenAI o3 testing, nearly everyone in tech has heard of it. But there is much more work to do to reach AGI. There remains many things that are easy for humans, but hard for AI.

ARC Prize Foundation

Changing the world, one library at a time.

We build centralized learning and internet centers in frontiner regions where people have almost no access to education or technology. Each center includes an English curriculum, books, tablets, Starlink internet, and a local coordinator. 

Khan Academy had digital distribution for middle class kids all over the world. libraryCreate will have physical distribution in education and remote work for the extremely impoverished around the world.

Once people are digitally trained, these learning centers will act as global nodes that companies can use for offshore, cheap work. This way, a libraryCreate center doubles as both a school and a place to work. This FDI then goes back into the community and helps stabilize economies and build metros.

Librarycreate

Reefs for Life is bringing life back to coral reefs and hope to the communities that depend on them.

Reefs for Life is transforming communities through conservation and restoring damaged coral reefs. We are bringing hope back to needy communities and life back to the ocean that they depend on to make a living. Partner with us and play a role in restoring tropical coral reefs in the Philippines.

Reefs for Life

A refreshingly simple data-driven game engine built in Rust. Free and Open Source Forever! 

Our mission is to promote, protect, and advance the free and open source [Bevy Engine](https://bevy.org/) and related open source projects. We coordinate and promote its continued maintenance and development, educate and train members of the general public in its usage, and conduct research and development to advance the state of the art of creating real-time applications and simulations.

In short: **we exist to develop Bevy and teach people how to use it!**

Bevy will always be free and open-source, but it isn't free to make! Because Bevy is free, we rely on the generosity of the Bevy community to fund our efforts. If you are a happy user of Bevy or you believe in our mission, please consider donating!

**Bevy Foundation** currently uses donations in the following ways:

- **Hiring Maintainers:** Maintainers are technical experts that facilitate the development of Bevy by reviewing, adjusting, and merging changes from the Bevy community, reviewing and developing designs, and choosing project direction. They are technical experts that contribute their own changes to Bevy, as well as social experts that ensure the Bevy community is a pleasant and effective place to work. Maintainers serve as public representatives of the project. Our bar for maintainership is high. See our [Bevy Organization](https://github.com/bevyengine/bevy/blob/main/docs/the_bevy_organization.md#maintainer) document for details.
- **Infrastructure:** The foundation will pay present and future hosting costs, such as hosting the Bevy website and continuous integration (CI) to validate our code. Currently these costs are low, but we expect them to increase over time.
- **Operational Costs:** Keeping a nonprofit organization compliant and operational takes time and money. These costs are currently very low, but we expect them to increase over time as we grow. Our goal is to minimize these costs as much as possible as our goal is to maximize the amount we spend on actually building Bevy and accomplishing our mission.

Bevy Foundation

Eliminating obstacles on the path to the comprehensive medical control of aging and age-related disease.

Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.

Longevity Escape Velocity Foundation

Our School's global impact would not be possible without the crucial support of our community of committed donors and friends. 

The London School of Hygiene & Tropical Medicine (LSHTM) is renowned for its world-leading research, postgraduate studies and continuing education in public and global health.

With your help, we can increase the number of scholarships we are able to offer. We receive thousands of applications every year, with funding only available to support a small number. 

Our diverse student body is what makes our community so special. Each year, your support funds our LSHTM Fund Scholars, enabling exceptional students to study at our School. We receive thousands of applications every year, with funding only available to support a small number. Without support, many brilliant students like this year's LSHTM Fund Scholar, Judy Baariu (MSc Public Health for Development, 2023) would not have been able to study with us.

LSHTM has over 3,500 staff conducting research in more than 100 countries, with core hubs in London and at the MRC Units in The Gambia and Uganda. Our outstanding, diverse and committed staff make an impact where it is most needed - deploying research in real time in response to crises, developing innovative programmes for major health threats, or training the next generations of public and global health leaders and researchers.

We help shape health policy and translate research findings into tangible impact. We are uniquely placed to lead on transformative approaches to global health and have 120 years of experience tackling big challenges. We are focused on finding new solutions to complex problems and acting upon this knowledge.

We work in collaboration with friends, partners, and supporters to achieve large-scale, long-term impact. Researchers at LSHTM explore all aspects of health challenges, from fundamental laboratory science to policy appraisal and analysis, encompassing statistical, clinical, laboratory, epidemiological and social science research globally.

Our aim is to build strong and dynamic leadership, push the frontiers of knowledge and make an impact where it is most needed. Philanthropy helps us achieve our mission; to improve health and health equity worldwide; working in partnership to achieve excellence in public and global health research, education and translation of knowledge into policy and practice.

London School of Hygiene & Tropical Medicine

Prevention, control and treatment of malaria and other communicable diseases among vulnerable populations.

Malaria Consortium US, Inc. (MC-US) is a registered 501(c)(3) public charity and shares the mission of Malaria Consortium, a globally recognized organization committed to reducing deaths and illnesses caused by malaria and other preventable and treatable diseases across Africa and Asia.

Our mission is to save lives and improve health in Africa and Asia through evidence-based programs that tackle malaria and other priority diseases while advancing universal health coverage (UHC). In the US, we build partnerships with foundations, donors, and philanthropic organizations to ensure that every contribution makes a lasting impact for those most in need.

As a leader in malaria control and elimination, our work focuses on interventions such as seasonal malaria chemoprevention (SMC), malaria vaccines, disease surveillance, and integrated child health services. We work in collaboration with governments, communities, and health systems to improve access to essential healthcare and strengthen delivery of services in underserved and hard-to-reach areas.

As a leader in interventions such as chemoprevention and vector control, we rely on evidence and our expertise to deliver established interventions, influence other effective interventions and guide new strategies to reduce the burden of malaria, pneumonia, dengue, malnutrition and diarrhea. We work with communities and all levels of the health system to improve access to and demand for primary healthcare services and overall quality of care.

Our tailored interventions seek to improve equity by providing quality, affordable health services to marginalized populations (particularly women and girls and those living in hard-to-reach areas). To ensure barriers to achieving UHC are addressed and to encourage sustainability, we work closely with governments to integrate our programs within existing health systems and structures in the countries in which we work.

We promote disease surveillance as a core intervention to engage communities to improve the quality and accessibility of routine health information by using digital tools and approaches that strengthen the linkages between case-level data and national health information systems. We combine capacity development at community level with the use of innovative tools and platforms to enhance local capabilities to interpret and use these data most effectively.

All of our work is informed by our core values: accountability, integrity, dignity and equity.

Malaria Consortium

Join our mission to maintain Typelevel projects, advance research and education in functional programming, and grow our community.

Typelevel Foundation

Empowering Youth in Cambodia helps disadvantaged urban youth access education, personal growth, and leadership opportunities.

Cambodia's youth demographic is one of the youngest in Southeast Asia, with over 60% of the population under 30. This rapid youth growth presents both a significant opportunity and a considerable challenge for the country’s future development.

**Empowering Youth in Cambodia (EYC)**, founded in 2006, focuses specifically on one of the most vulnerable segments of this youth population—those living in disadvantaged urban communities in Phnom Penh. Most parents of EYC students work in informal sectors as factory workers, waste pickers, tuk-tuk drivers, or street vendors, earning only a modest daily income—typically between $5 and $8. These jobs are unstable and lack job security, often leaving families living on less than $200 per month. Many of these young people are first-generation learners, balancing studies and work often without family support. Additionally, they face limited access to quality education and stable employment opportunities.

**EYC’s mission is to empower these youth through education, personal development, and leadership opportunities—helping them break the cycle of poverty and become active, contributing citizens.** 

Starting small with English and computer classes in Phnom Penh, EYC quickly grew into a respected NGO, reaching over 800 youth annually. Alumni became the organization’s backbone—returning as staff members, volunteers, and role models, creating a powerful youth-to-youth cycle of empowerment. 

Over the years, EYC expanded to multiple community centers, added programs like scholarships, leadership training, life skills, sports, arts, and STEM education. The scholarship program, in particular, has helped many students become the first in their families to graduate from high school and attend university. 

Today, EYC operates three vibrant community centers in Phnom Penh, offering a range of programs:

- **English, digital literacy, and STEM courses,** including coding and robotics
- **Scholarship support** for high school and university students
- **Leadership development** to build communication, teamwork, and critical thinking skills
- **Life skills and extracurricular activities** in sports, arts, and mental health initiatives
- **Career guidance** and employability support
- **Volunteer and community engagement opportunities** with local and international partners

EYC’s holistic approach promotes not only academic skills but also confidence, resilience, and leadership. Its partnerships with other NGOs, the private sector, and educational institutions have expanded impact and trust within communities.

Looking ahead, EYC aims to strengthen its curricula, increase digital adoption, expand career pathways, deepen partnerships, and diversify funding to ensure long-term resilience. Its ultimate vision is to be a model for youth empowerment in Cambodia—demonstrating how community-driven initiatives can transform lives, break cycles of poverty, and foster a new generation of leaders.

**Join us** in supporting EYC’s mission to unlock the potential of Cambodia’s youth and create a brighter future for all.

Empowering Youth in Cambodia

The Vision of the EWT is a healthy planet and an equitable world that values and sustains the diversity of all life.

The EWT is among South Africa’s largest and
most established national non-governmental
conservation organizations.  Founded in 1973, we are a non-profit organization with an expanding footprint
throughout southern and East Africa, focusing
on conserving threatened species and ecosystems to the benefit of people. We achieve this by conducting on-the-ground research, supporting community-led conservation, training and building capacity, addressing human-wildlife conflict, monitoring threatened species, and establishing safe spaces for wildlife range expansion.

The EWT works with key partners, including
communities, businesses, landowners, academic
institutions, and governments, to create a
sustainable future for wildlife and people.
 The Endangered Wildlife Trust is dedicated to
conserving threatened species and ecosystems in southern and East Africa to the benefit of all.

The EWT achieves this mission by delivering on
three strategic imperatives: Saving species,
conserving habitats, and benefiting people.
OUR STRATEGY
Our conservation programmes form the
organization’s backbone, harnessing the talent
and enthusiasm of a dynamic team of
individuals whose unique exper􀆟se and
mo􀆟va􀆟on provide them with the tools to
respond to the challenges they face in pursuit
of saving our most threatened species and
ecosystems.
The EWT is a registered Trust governed in accordance with the Trust Property Control Act No. 57 of 1988, under Master’s reference number IT 6247. The EWT is also registered in South Africa as a Non-Profit Organisation, registration number 015- 502 NPO
and Public Benefit Organisation, registration number 930 001 777

SPECIES RECOVERY
The EWT has achieved remarkable gains for many species, where downward trends in the local populations of Wattled and Grey Crowned Cranes, Piggersgill’s Frogs, the Amathole Toad, and the Riverine Rabbit have joined the Cheetah as species on a pathway to recovery. Critically Endangered
Wattled Cranes are increasing in number, now estimated at some 320 birds nationally, up 60% from their lowest numbers. The EWT has also helped reverse the decline of Endangered Grey Crowned Cranes, while Blue Crane numbers have increased from an estimated 25,500 birds nationally in 2007 to some 30,000 birds today.
SPACE FOR SPECIES
Through our range expansion work, we have secured and protected safe spaces for multiple species to thrive and we have reintroduced many threatened species back into secure and suitable landscapes. Safe space for African Wild Dogs has increased to over 1.4 million ha throughout southern Africa and their numbers and generic health have followed suit. Safe space for Cheetahs and their numbers have also increased from 217 Cheetahs on 41 reserves in South Africa in 2011, to 470 Cheetahs on 65 reserves covering over two million hectares across southern Africa.

SAFEGUARDING OUR SPECIES
To protect threatened species, we monitor them and work with partners, businesses, landowners, and communities to reduce the threats they face. We are innovating to achieve bigger impacts, as evident in our drone project’s expansion to use drones to mark power lines - reducing bird strikes safely and affordably and monitor Southern Right Whales in a way that wasn’t possible before. We continue to explore the use of eDNA to identify the presence of elusive and potentially extinct species, such as
Van Zyl’s and De Winton’s Golden Moles, so that action can be taken to save the last of their habitats.

Our pioneering Eye in the Sky carcass and wildlife poisoning detection project has already saved thousands of animals from secondary poisoning as a result of its efficient and effective success and our quick response times. The project uses the movements and behavior patterns of GPS-tracked vultures to remotely detect potential poisoning events and respond to these rapidly, alerting rangers on the ground and preventing further loss of wildlife to poisoning. We also contribute to preventing wildlife crime through the deployment of Conservation K9s to detect wildlife contraband and track poachers. These dogs help us to protect species, including rhinos, elephants, and pangolins.

Protec􀆟ng and conserving natural places is one of the most important strategies for comba􀆫ng the effects of
biodiversity loss and climate change. The EWT conserves habitats by reducing habitat loss and improving the
ecological integrity of threatened ecosystems through rehabilita􀆟on, restora􀆟on, and sustainable land
management. Many of the EWT’s programmes are involved in habitat conservation, but two are dedicated to protecting specific habitats.

COLLABORATING FOR CONSERVATION
An effective vehicle for conserving habitats is the formal protection of land through Biodiversity Stewardship. We work with private and community landowners to legally declare their land as protected or help them to manage it sustainably and without damage to sensitive species and ecosystems.
The EWT was instrumental in the development of Biodiversity Stewardship, having facilitated the workshops which led to its establishment, and subsequently, the EWT has declared 185 properties (over 139,000 ha) as protected areas in the last
ten years and is currently in the process of securing a further 130,000 hectares for threatened species conservation across South Africa. This includes proper􀆟es in one of the region’s most important centres of endemism: the Soutpansberg Mountain Range. Easily recognized for our work to safeguard charisma􀆟c species like the Wild Dog and Cheetah, the EWT also played a key role in preventing the extinction of the Brenton Blue Butterfly by establishing a dedicated reserve for this endemic insect.  Other critical habitats have been protected to prevent the extinction of many smaller, lesser-known species, including rep􀆟les, amphibians, butterflies, golden moles, and threatened plants.

CARBON FOR CONSERVATION
After establishing the feasibility of carbon trading in South Africa’s grasslands and recognizing the potential benefits for farmers and grassland and wetland management, the EWT the EWT initiated the first carbon offsetting contracts with private landowners in South Africa, in the Drakensberg.
When landowners agree to conserve and manage their land to allow for the verifiable sequestration of carbon in the soil, the carbon can be converted into carbon credits. Liable ensures, usually big carbon emitters, can purchase up to 10% of their carbon as carbon credits to reduce their tax liability in South Africa. These purchases create a long-term revenue stream for farmers and conservation organizations to support conservation efforts and protect important habitats through improved land-use management.

People need nature to survive – it provides important resources we depend on. We must live in harmony
with nature to thrive in healthy ecosystems that will support us and future genera􀆟ons, our wildlife, and
maintain our rich natural and cultural heritage. Through two of its programmes, the EWT implements
innovative strategies that incorporate the needs of people and the environment to ensure that people
benefit from the more sustainable use of natural resources.
BENEFITTING PEOPLE
CAPACITY FOR CONSERVATION
Working across diverse landscapes such as wetlands,
grasslands, river catchments, savannahs, and mountains, the EWT has embraced the need to support the lives and livelihoods of thousands of people who depend on their local environment, from developing sustainable livelihoods as alternatives to environmentally destructive practices in communities from KwaZulu-Natal to Limpopo, Zambia, and as far as Uganda, to pioneering the implementation of Population, Health and Environment in communities in southern and East Africa to support sustainable communities and empower women. The EWT
promotes and implements the education of school
learners and builds capacity for conservation and
ecotourism in communities across our project areas.

BIODIVERSITY AND BUSINESS
Recognizing the importance of biodiversity to business, the EWT established the National Biodiversity and Business Network (NBBN) in 2013 to work with innovative businesses to identify and manage the risks and opportunities resulting from their interactions with the natural world. Through its Biodiversity Disclosure Project, the NBBN helps companies to understand, measure, and disclose their biodiversity impacts and policies. The NBBN introduced the world’s first standardized accounting
framework, the Biological Diversity Protocol (BDP), which measures a business’ impact on biodiversity and identifies areas of improvement over time.  The EWT’s targeted conservation work has national and global impacts and our achievements contribute to multiple conservation-related frameworks. These include South Africa’s 2nd National Biodiversity Strategy and Action Plan (2015–2025), and the National Biodiversity Assessment which assess the status of, and identify the biodiversity and ecosystem
management priori􀆟es as well as the International Union for Conservation of Nature (IUCN) Red List of Threatened Species. 

Arguably, the EWT’s most important global impact is our work toward achieving the Sustainable Development Goals (SDGs), a collection of 17 interlinked global goals designed by the United Nations. The SDGs are a universal set of goals, targets, and indicators that UN member states should use to frame their agendas and political policies. Ambitious by nature, they are a government-led endeavor that serves to coordinate actions by United Nations agencies, businesses, non-governmental groups, and any other entities working on specific goals. These are
the goals that the EWT contributes to.



Endangered Wildlife Trust

Non-Trivial is empowering the youngest researchers tackling the world’s most pressing problems. 

**Join us in building the world's most exceptional research community for young people**

Non-Trivial has grown from an idea to one of the most selective program of its kind—450 fellows chosen from 40,000+ applicants in just two years. Our participants gain the research experience that helps set them apart. They're already publishing at top machine learning conferences, co-authoring reports for the UN, and tackling humanity's biggest challenges.

**Why your support matters:**

Every donation strengthens the entire community. When you help us provide scholarships and world-class mentorship, you're ensuring that:

- The brightest minds can participate regardless of financial background
- Your child learns alongside truly exceptional peers (average SAT: 1560)
- The quality bar stays impossibly high (0.75% acceptance rate)
- Research with real impact remains the standard

**What sets us apart:**

- **Proven outcomes**: 57% attend Ivy/top-10 universities; 30% of Oxford's prestigious Ellison Scholars are our alumni
- **Authentic research**: Publications, not simulations. Our teens work on problems that matter.
- **Zero barriers**: Completely free. Merit is the only currency.
- **Expert guidance**: One-on-one mentorship from leading researchers

When you support Non-Trivial, you're ensuring that financial constraints never prevent a brilliant mind from joining this community. You're also maintaining the exceptional standards that make participation so valuable—including for your own child.

Non-Trivial

The DSS empowers creators to imagine & build equitable, just, regenerative futures through art, design, community & collaboration.

The **Design Science Studio** (DSS) is a cultural and educational incubator that supports creators in shaping futures rooted in regeneration, justice and belonging. We are a living ecosystem of artists, designers, systems thinkers, story-weavers and movement builders committed to creating a world that works for all of life.

DSS holds space for interdisciplinary collaboration, creative capacity-building and community-rooted innovation. Our work is deeply informed by the legacy of Buckminster Fuller and carried forward through decentralized and decolonial ways of being, imagining and doing.

At the heart of our ecosystem is the **(r)Evolutionary incubator** —a 7-month journey of creative emergence and collective evolution that centers artists and designers as cultural stewards and worldbuilders. It weaves together art, design science, storytelling, systems thinking and regenerative design, offering an invitation to grow alongside others who are working to create futures rooted in care, justice and imagination.

**Each program cycle includes:**

- 144 participating artists
- 30+ mentors
- 50 visionary guest speakers
- 4 global salons for deep learning and connection
- Digital and in-person exhibitions

Support a global commUnity of creative peers

Design Science Studio

Holding The Hyperscalers Accountable: We monitor leading AI companies to ensure transparency, privacy, and ethics are maintained.

**The Midas Project is a watchdog nonprofit working to ensure that AI technology benefits everybody, not just the companies developing it.**

We lead strategic initiatives to monitor tech companies, counter corporate propaganda, raise awareness about corner-cutting, and advocate for the responsible development of emerging technology.

The Midas Project

Sentinel transforms pandemic prevention and response through cutting-edge technology, global collaboration, and local empowerment.

Infectious disease outbreaks have caused more illness, death, and economic loss than any other crisis in history. Pathogens kill millions of people each year and hit the most vulnerable communities the hardest. They go further—exposing and exploiting the deepest cracks in our societies and the risks are rising. 

 The forces driving pandemics are accelerating. Climate change is increasing human exposure to pathogens through animals and insects. Habitat encroachment and industrial agriculture are raising the risk of spillover. Global trade and travel speed disease spread, while conflict and instability weaken health systems. New biotechnologies pose engineered threats that current systems cannot detect. Over the past decade, the number of epidemics has grown by 20% worldwide. Between February and June 2025 alone, more than 70 outbreaks were reported across Africa. Yet global readiness is faltering. In the past year, U.S. investments in frontline health systems and disease surveillance have been sharply reduced. Funding cuts have disrupted networks and delayed the deployment of critical tools, especially in regions most vulnerable to outbreaks. Health programs across West and Central Africa now face rising threats with fewer resources and limited external support, leaving the world more exposed- with some experts estimating the probability of a pandemic in the next decade to exceed one in four.
 
Amid these mounting challenges, we stand at a historic moment of possibility. Sentinel, a pandemic early warning prevention and response program, is built to meet this moment: a locally led, technology-enabled model for proactive public health, integrating diagnostics, data, and training to stop outbreaks before they spread. 

Sentinel is an outbreak surveillance framework, designed to detect pathogenic threats in real-time and prepare the global community to stop diseases before they spread. It brings advanced science to the frontlines through a next-generation pandemic prevention system built around three core pillars. DETECT delivers rapid diagnostics and genomic surveillance. CONNECT integrates laboratory, clinical, and genomic data into real-time insights. EMPOWER invests in training, infrastructure, and institutional capacity so countries can lead their own outbreak responses.

DETECT: Timely diagnostics and sequencing are essential for early outbreak detection and effective response. Yet these capabilities remain limited in many LMICs, even for high-priority pathogens like Lassa, Ebola, and Marburg. Too often, health systems act only after outbreaks are widespread, costing precious time and lives. Sentinel’s DETECT pillar delivers speed, affordability, and accessibility through a tiered approach to diagnostic design and implementation.

CONNECT: Fragmented systems delay response and allow outbreaks to spread unchecked. When data are siloed, public health leaders lose time and visibility, undermining containment efforts. In contrast, integrated systems support faster, more effective action. Sentinel’s CONNECT pillar builds the digital backbone for outbreak response. Through interoperable dashboards and analytic platforms, it streamlines data flow, strengthens each stage of detection, analysis, and control, and enables real-time decision-making.

EMPOWER: Building local leadership and scientific capacity is central to Sentinel’s mission. Although over 60% of emerging infectious diseases originate in Africa and Asia, fewer than 10% of African countries had genomic surveillance at the start of COVID-19. Africa faces a shortfall of more than one million health workers, including critical gaps in genomics and data science. Sentinel’s EMPOWER pillar builds sustainable, locally led outbreak response by investing in people and communities. It enables local experts to detect and respond early with solutions grounded in context, shortening the path from innovation to public health practice and building resilient systems from within.

The foundation for Sentinel was laid over two decades through a 20-year partnership between Prof. Christian Happi, a Nigerian infectious disease expert, and Prof. Pardis Sabeti, a U.S.-based computational geneticist. Over the years this collaboration has established operational programs in Nigeria and Sierra Leone that connect health workers in rural clinics and hospitals with national and international public health leadership. **To date more than 3,000 public health workers from 53 of 54 countries in Africa** have been trained through Sentinel’s approach.

Sentinel-supported teams have enabled early detection and rapid response to Marburg, mpox, Lassa, dengue, and COVID-19, providing critical data to inform government action. 

COVID-19: Sentinel rapidly expanded genomic and diagnostic capacity across Africa, establishing pipelines with national partners. In March 2020, IGH sequenced Africa’s first SARS-CoV-2 genome within 72 hours of sample receipt. Sentinel supported testing for over 30 million people, deployed SHINE and CARMEN technologies, and led genomic surveillance in 26 countries. This work helped identify one of the first globally recognized variants of concern. Sentinel also trained scientists from 53 African countries, strengthening long-term preparedness. The Sentinel team also led one of the largest diagnostic and sequencing centers in the U.S. and supported global data sharing and informatics efforts.

Mpox: In 2023, Sentinel traced an mpox outbreak in Nigeria to oil workers in Rivers State, guiding the NCDC’s targeted vaccination strategy. Sentinel also hosted a three-week genomics bootcamp that trained regional professionals in real-time sequencing and analysis. Genomic data revealed sustained human transmission of the West African subtype, with signs of adaptation and rising pandemic potential. When an outbreak emerged in Sierra Leone in 2024, local public health teams, supported by Sentinel, initiated sequencing and shared real-time data. Analysis identified a new highly transmissible G.1 variant spreading beyond previously affected groups. Sentinel tools and team members remain central to guiding the national response.

 Marburg: In 2024, Sentinel supported the Rwandan government during a Marburg outbreak in Kigali. IGH provided outbreak reconstruction and real- time sequencing, while Prof. Happi co-chaired the national scientific response. The outbreak was contained at 66 cases, with the case fatality rate reduced to 22%, far below historical averages.

Building off of these successes, Sentinel is poised for its next phase: deepening national integration, expanding its reach, and advancing a globally transferable model for pandemic prevention. We will achieve full national implementation in Sierra Leone and move toward this in Nigeria, embedding surveillance into national systems and incorporating a One Health approach that addresses climate-linked and zoonotic threats. Expansion will continue to Senegal, Rwanda, and the Democratic Republic of Congo, where strong partners and readiness are in place. In parallel, we are globalizing Sentinel’s tools, data platforms, and training programs to create a lasting framework for pandemic prevention.

Sentinel will help millions benefit from earlier detection, faster response, stronger systems, and a globally connected early warning network. This is the moment to transform pandemic prevention and safeguard global health security for generations to come.

There will be another pandemic virus in our lifetimes—it may already be here, but our work is about more than stopping disease outbreaks. By empowering people and equipping them with the tools, the system, and the knowledge needed, we create strong and resilient communities for generations to come. Sentinel is about partnership, solidarity, and most importantly, hope!

That's why we believe that with you, we can make an impact.

Sentinel 

An institute dedicated to spreading and applying humanity's deepest and most consequential ideas.

Understanding how knowledge grows (the primary concern of *epistemology*) is one of the most fundamental questions that humanity has ever asked. Because the growth of knowledge plays a role in every human endeavor–from science to politics to creating artificial intelligence to raising children to entrepreneurship–getting the answer wrong necessarily leads to blind alleys and errors. Fortunately, Karl Popper, David Deutsch, and other thinkers have discovered and elaborated upon the right answer: that knowledge grows via conjecture and criticism.

Such a simple idea (the entire theory of which is called *critical rationalism*) has an enormous number of practical implications for all of the aforementioned fields and any other in which humans can make progress. While the revolutions brought forth by Newton, Darwin, and Einstein were profound and improved mankind's lot in the universe, even they were limited to particular strands of human endeavors. But epistemology is universal for any problem a person or society faces. Therefore, spreading critical rationalism and its implications will dissolve barriers to progress that most people do not even know stand in their way.

Conjecture Institute Inc

A research nonprofit that works on assessing whether cutting-edge AI systems could pose catastrophic risks to society.

METR (Model Evaluation and Threat Research) builds the science of accurately assessing risks, so that humanity is informed before developing transformative AI systems.

We believe that AI could change the world quickly and drastically, with potential for both enormous good and enormous harm. We also believe it’s hard to predict exactly when and how this might happen.

At some point, AIs will probably be able to do most of what humans can do, including developing new technologies; starting businesses and making money; finding new cybersecurity exploits and fixes; and more.

We think it’s very plausible that AI systems could end up pursuing goals that are at odds with a thriving civilization. This could be due to someone’s deliberate effort to cause chaos, or happen despite the intention to only develop AI systems that are safe.

Given how quickly things could play out, we don’t think it’s good enough to “wait and see” whether there are dangers.

We believe in vigilantly, continually assessing risks. If an AI brings significant risk of a global catastrophe, the decision to develop and/or release it can’t lie only with the company that creates it.

METR

Abortion Freedom Fund supports accessible, affordable, evidence-based abortion pills by mail for all. 

Abortion Freedom Fund is a national fund focusing on funding abortion pills by mail.

Abortion Freedom Fund supports accessible, affordable, evidence-based abortion pills by mail for all. Our mission is to help pregnant people take control of their healthcare and futures by dismantling medicalized control of abortion and encouraging a world where abortion pills are over the counter.

We simplify access to care for patients by funding virtual abortion providers and clinics, individuals accessing telehealth abortions, and reimbursing local funds for telehealth abortion care, allowing them to focus their resources on people seeking procedural abortions in their communities.

In addition to direct funding, we partner with organizations doing research and other activism to increase access to abortions.

Our core aims are:
-Assisting people who are pregnant to take control of their health care and futures
-Dismantling medicalized control of abortion and encouraging a world where abortion pills are over the counter
-Advocating for the full continuum of abortion care from self managed to clinician supported
-Breaking down the stereotype that abortion pills are dangerous

Abortion Freedom Fund

Spritely Institute builds, researches, and standardizes networked technology which put people and communities first.


Centralized social media is harmful to society. We are building a gatekeeper-free decentralized system. Our mission is “social media done right”, to put people in control of their own identity and build the technology that would enable a shift to collaborative and intentional security models prioritizing active consent. To accomplish this, we will build a new architecture for the internet: removing the necessity of client-server architecture, replacing it with a participatory peer-centric model.

Spritely’s technology is being released as free and open source software aiming for multiple programming language implementations and eventual open standardization. All of our work, ranging from decentralized identity, peer-to-peer user agents, decentralized social networks, encrypted and portable storage, and distributed object programming infrastructure is being built to enable a gatekeeper-free path where users and content are not tied to a specific server.

Spritely Networked Communities Institute

Let's dream together better!  Exploring wisdom for a world of magical technologies with paleontologist-futurist Michael Garfield.

**If you could do anything with technology, what will you do?**

Humans On The Loop is a transdisciplinary inquiry into the nature of agency in our age of automation.

In our AI-infused society, the gap between imagination and “reality” is smaller than it’s ever been — and now it’s time for humankind to graduate from asking if our dreams are possible to asking how we can dream better. This means cultivating deeper self-awareness, more discipline and humility, and a better metaphysics of technology to help us wield these new superpowers. But decades into a period of rapid information scaling, our grasp of consensus reality and executive function have eroded, causing an epistemic crisis. The wicked problems of this century require coordination at unprecedented scale, but our greatest natural resource — attention — has worn even thinner than our topsoil. How do we regenerate it and restore the faculties we need to be good stewards of this new ecology of minds?

Navigating the challenges that come with new information technologies is a group exercise and demands inherently plural approaches. The right response to tools that amplify our biases is to lean in with curiosity and play, not fearI have spent two decades studying and synthesizing  perspectives on intelligence and technology, innovation, and human-technology co-evolution…as well as testing bleeding-edge creative tools in public, helping cultivate systems literacies for navigating transformation, and fostering a massive network of mentors and collaborators with whom I share a devotion to the cultivation of a healthy Biosphere and Technosphere. As AI comes of age, this is the moment to recruit as many of them as we can into a multimodal public inquiry on wisdom and technology, power and responsibility, holistic practices for cultivating saner futures…and how we can keep Humans On The Loop and at the wheel.

It's going to be a trip — how can we make sure that it’s a good one?

This project exists to foster a renaissance of collaboration and the conditions for new ways of knowing. Its goals include to:

– Boost public discourse at the intersection of technology and wisdom
– Create a legacy of public goods that help train instruments for deepening our understanding
– Prototype and demonstrate experimental tools for thought
– Promote the adoption of reflexive AI for both private and public good
– Help map the emergent ecosystem of changemaking orgs and wise innovators
– Fertilize new narratives and strategies for navigating "wicked problems"
– Bridge domains and cultures in positive-sum collaboration

***Explore this project's [vision document](https://docs.google.com/document/d/1kIoDlRD721UhZW4SjXIeccpCo2-v3ngoF1iZDwNyfPU/edit?usp=sharing), [pitch deck](https://bit.ly/hotl-slideshow), and* [essay/podcast archive](https://michaelgarfield.substack.com/t/humans-on-the-loop)*.***
***[Subscribe](https://michaelgarfield.substack.com/subscribe) for weekly dialogues plus articles, reviews, monthly hangouts, and more.* And please** [email my secure inbox](mailto:humansontheloop@proton.me) **with questions or partnership requests!**

Humans On The Loop

CETI is a nonprofit org applying advanced machine learning and gentle robotics to listen to and translate whale communication. 

Founded in 2020 as a TED Audacious Project, the organization’s science team is made up of the world's leading artificial intelligence and natural language processing experts, marine biologists, cryptographers, linguists, roboticists and underwater acousticians. CETI’s research is taking place off of the island of Dominica in the Caribbean.

In the late 1960s, scientists, including Dr. Roger Payne, a principal advisor of CETI, discovered that whales sing to one another. His recordings, Songs of the Humpback Whale, sparked the “Save the Whales” movement, one of the most successful conservation initiatives in history. The campaign eventually led to the Marine Mammal Protection Act that marked the end of large-scale whaling and saved several whale populations from extinction. 

All this by just hearing the sounds of whales. Imagine what would happen if we could understand them?

WHY WHALES 
Sperm whales specifically share traits strikingly similar to humans. They live in matriarchal and multicultural societies and share dialects and strong multigenerational family bonds. Sperm whales have the largest brains of any species and have higher-level functions such as conscious thought and future planning, as well as speech and feelings of compassion, love, suffering and intuition. Their vocalizations, among the loudest animal sounds on the planet, have a Morse code-like structure that shares the hallmarks of a highly-evolved language. Our understanding of these animals and their dialects is still in its infancy. Only in the last fifteen years have we begun to learn how some of their vocalizations are used for communication.  
WHAT CETI IS DOING
CETI is:
-Developing non-invasive robotics to listen to a population of whales in the Caribbean and put their sounds into context.
-Deploying a “Core Whale Listening System,” an innovative hydrophone array, underwater robotic gliders, custom bioinspired whale tags and other technology to gently study the whales.
-Building on substantial data on the whales’ sounds, social lives, and behavior already obtained by the Dominica Sperm Whale Project. 
-Creating a bespoke, big-data pipeline to examine the recorded data and decode it using advanced machine learning, natural language processing and data science.
-Publishing a series of academic papers beginning with the CETI roadmap.
-Collaborating with the National Geographic Society, including their Exploration Technology Lab, and amplifying the project across National Geographic’s storytelling and education channels.
-Implementing community-based programs like the Dominica Marine Conservation Fellowship, a community-based 10-month multi- module training program for young Dominicans interested in marine science, that was developed in partnership with National Geographic.
-Launching various communications projects to tell CETI’s story including a public interface for the citizen science community, resources for educators and children and arts programs.

IMPACT
Now, for the first time in history, it’s possible to use artificial intelligence to identify and interpret deep structure within animal communication. Using these technologies, CETI is building on the legacy of the “Save the Whales” movement with the goal of having an impact by contributing the following:
Interspecies Communication - A new data set of unprecedented size to the rapidly expanding field of interspecies communication and a roadmap of how humans could translate the communication of any other species
Marine Biology - A substantive contribution to the field of whale research within marine biology that opens gateways for future research initiatives. 
Policy - New information about whales that can bolster policy efforts to protect marine mammals and ocean habitats. Policy advances in this area are crucial as six out of the 13 “great” whale species (the largest whales) are still endangered (World Wildlife Federation). To ensure impact in this area, CETI plans to build out policy campaigns and initiatives. 
Perspective - It is widely endorsed that connectivity with nature can improve mental health. By sharing its journey and findings with the public, CETI hopes to contribute to a feeling of increased wonder and connectedness to whales and the ocean that can inspire action. CETI will build out arts and childrens’ initiatives in support of this impact goal.
Conservation - CETI’s first phase of research is taking place in Dominica in the Caribbean, a region that is one of the world’s greatest centers of diversity. By carrying out its research in partnership with local stakeholders, CETI hopes to contribute to regionally-led research and conservation efforts.

HOW CETI IS SUPPORTING DOMINICA
-CETI’s capacity-building initiative, Dominica Marine Conservation Fellowship is a 10-month, nine module training program for young Dominicans interested in marine science) in partnership with National Geographic.  The program has three 2022/2023 fellows and partnerships with the Dominica National Youth Council, Dominica State College and Dominica’s Ministry of Education. The program’s curriculum (co-created with National Geographic) includes modules on marine science, scientific research/techniques, water and vessel skills and storytelling and leadership among other topics.
-All research and findings by CETI in Dominica are all open-source and will be available for Dominica. The organization’s sailing research vessel (CETI-1), a Rigid Inflatable Boat (CETI-2) and Dominican made boat (CETI-3) are in operation in Dominican waters; these boats along with other CETI equipment will be donated to the local entity at the completion of the project.
-A temporary field station has been established in Dominica and has the capacity to host 10-12 researchers, fellows and students. In the long-term, CETI plans to build a permanent field station in Dominica 
-In 2023, CETI will continue local engagement and presentations with primary and secondary schools, development of video content for use in classrooms, collaborations with local artists and collaborations with local stakeholders such as marine and dive operators, civil society organizations and schools.



Project CETI

Communicating the best research and data to understand big global problems and make progress against them

Poverty, disease, hunger, climate change, war, existential risks, and inequality: The world faces many great and terrifying problems. Our World in Data focuses on communicating the best research and data that helps us understand and find solutions to the world’s largest problems.


Our World in Data publishes an open-access publication where users can understand the state of the world today, where we are making progress and where we are falling behind. Through interactive data visualizations we can see how the world has changed; by summarizing the scientific literature we can understand why. We cover everything from global poverty to natural disasters, education and health, democracy; we have over 13,000 charts across hundreds of topics.


Our World in Data is free, open-source and provided as a public good. It has millions of users every month, and is cited in research and media across the world every day. This allows millions of people to understand the large problems the world is facing, and how we can solve them.

Our World in Data

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founder @ camp.org, expa.com, uber.com & mix.com

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