Instead of gifts, I’m celebrating my birthday this year by raising funds for **ClusterFree**, an organisation tackling extreme suffering most people have never heard of. Effective treatments for cluster headache exist, from high-flow oxygen to novel compounds in clinical trials, yet most patients worldwide face enormous barriers to accessing them due to diagnostic delays, lack of medical awareness, regulatory restrictions, and inadequate insurance coverage.

ClusterFree is working to change that through advocacy, research, and awareness. Your donation funds their core operations and helps expand their impact, from publishing treatment guides in multiple languages to advocating for policy changes that could help millions get access to pain relief.

Help ClusterFree Battle one of the Most Painful Conditions

The world's most painful condition demands urgent action. Help us accelerate access to effective treatments for cluster headaches.

Our goal is to help millions of cluster headache patients access safe, effective pain relief treatments as soon as possible. Their pain cannot go unnoticed for one more day.

**About cluster headache**

Cluster headache ("suicide headache") is often considered the most painful medical condition. Patients [rate it](https://doi.org/10.1111/head.14021) as significantly more painful than childbirth, kidney stones, gunshot wounds, and bone fractures. Standard painkillers don't help.

Even in wealthy nations with advanced healthcare, **hundreds of thousands** still experience torture-like suffering every year. About 50% of all patients have contemplated suicide. At the same time, global funding for cluster headache is virtually nonexistent. **This crisis cannot go on any longer**

Effective treatments for cluster headache exist, from high-flow oxygen to novel compounds currently being studied in clinical trials. Yet most patients worldwide face enormous barriers to accessing them due to long diagnostic delays, lack of medical awareness, regulatory restrictions, and inadequate insurance coverage. Some of the most promising treatments (such as psychedelics of the indoleamine family) remain illegal in most countries, forcing patients to break the law to treat their pain.

**Our work**

To minimize the suffering caused by cluster headaches, we currently focus on three areas:

1. **Helping patients find effective treatments sooner.** We publish [ClusterInfo](https://www.clusterinfo.org/), a growing repository of free, multilingual guides on how to treat cluster headaches, from high-flow oxygen to off-label options.
2. **Advancing research into new treatments.** We conduct and support research into promising treatments for cluster headache, prioritizing indoleamines, a family of compounds that are highly effective and remarkably safe at low doses.
3. **Advocacy.** We advocate for universal access to effective treatments and increased research funding, through open letters to decision-makers and by working to include cluster headache in Right to Try and Compassionate Use programs in various jurisdictions.

[**Learn more**](https://clusterfree.org/about)

ClusterFree

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We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

Choose a donation for Every.org

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Help ClusterFree Battle one of the Most Painful Conditions

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