The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

Karl Coke Evangelistic Association Incorporated is a nonprofit organization focusing on Timothy International University.

At Timothy International University, we combine rigorous academic training with a deep spiritual foundation to equip individuals with the knowledge and tools needed to explore the Bible from its roots. Accredited by the Transworld Accrediting Commission International, we are committed to inspiring and empowering Christian families, leaders, and individuals to become effective stewards of God’s Word.

Timothy Seminaries International

We match donations to any charity you choose while introducing you to super-effective charities. Learn more: GivingMultiplier.org

[**Giving Multiplier**](https://givingmultiplier.org) is a research project created at Harvard University that adds matching funds to any charity of your choice while introducing donors to highly effective charities recommended by experts.

*Resources:*

- [Make a donation that gets matched](https://givingmultiplier.org)
- [Become a matching funder](http://givingmultiplier.org/matching) (Donations made on this page will also go toward our matching system.)
- [Sign up to our newsletter](http://eepurl.com/i0GHhc)
- [Learn about our philosophy](https://givingmultiplier.org/philosophy)

Questions? Email us: **info@givingmultiplier.org**

Giving Multiplier

American Friends of Institut Curie - Marie Curie Research and Cancer Care Center in Paris

Follow in the footsteps of Marie Curie and join the fight against cancer 
 
 A leading player in the fight against cancer, Institut Curie - Marie Curie Research and Cancer Care Center in Paris brings together an  internationally-renowned research center  (1,200 researchers from 80 countries) and an  advanced hospital group  that provides care for all types of cancer – including the rarest forms. Founded in 1909 by  Nobel laureate Marie Curie , Institut Curie is historically located in the heart of Paris, France but also in the nearby cities of Saint-Cloud and Orsay with a  cutting-edge protontherapy center .  Every day, more than 3,600 researchers, physicians, caregivers,technicians, and administrators work together to defeat cancer. Institut Curie's work is built on three essential approaches: 
 Research 
 Care 
 Preserving an transferring knowledge 
 Institut Curie's Research Center promotes interdisciplinaryresearch through 12 mixed research units.  Translational research lies at the interface between basic and clinical research, aimed at facilitating and accelerating exchanges between cognitive research and research oriented towards patients and care. OUR PROJETC : BUILDING THE FIRST CHEMICAL BIOLOGY CENTER SPECIALIZED ON CELL'S PLASTICITY IN THE WORLD Institut Curie plays a major role in international chemical biology research thanks to the work of Dr. Raphaël Rodriguez and his team and their recentground-breaking discovery on the role of iron in the metastatic dissemination. Institut Curie is building the Chemical Biology Research Center to support and build on this work by recruiting international research teams andlaunching new multidisciplinary research approaches. It is the first center in Europe specialized in addressing fundamental questions in cancer cellplasticity and its link to metastatic spread and cancer treatment. The new Chemical Biology Research Center will be co-directed by Dr. Fatima Mechta-Grigoriou, PhD and Dr. Raphaël Rodriguez, PhD. The Chemical Biology Research Center will support research to: 
 Study cancer cell activity in a biologicaland chemical level, discover new biological features underlying cancer progression 
 Identify and develop small molecules to be used for new treatment aiming to target cancer cell plasticity and block cancer cells from spreading 
 Discover new druggable targets, design new therapeutic angles and pathways to cure cancer 
 
 
 ABOUT CHEMICAL BIOLOGY 
 Chemical biology is the work in chemistry which is of biological interest and to that work in biology in which the chemical approach is used to solve biological problems.  Dr. Linus Pauling 
 Chemical biology is one of the fastest growing areas of cancer research today. This field of research has the potential to uncover the underlying causes of cancer progression and find out how to stop cancers from spreading to different parts of the body, also called metastasizing. Today, metastasis causes 90% of cancer deaths. Finding the key to block metastatic spread will have a tremendous impact on cancer survival and discovering pathways to a cure. Chemical biology uses of chemical principles and tools to solve pressing problems in biomedical research that are challenging to address using classical methods, such as those routinely used in cell biology, genetics, and biochemistry. The discipline involves chemists and biologists to work together on small molecules that have the potential to impact patient care one day if turned into drugs. 

As a private charitable foundation since 1921 Institut Curie is supported by donations, grants and bequest. Your support is essential to save more lives.  Together, let's beat cancer! 

Institut Curie - Marie Curie Research and Cancer Care Center

Zig is a general-purpose programming language and toolchain for maintaining robust, optimal, and reusable software.

The Zig Software Foundation is a non-profit corporation founded in 2020 by Andrew Kelley, the creator of Zig, with the goal of supporting the development of the language. Currently, the ZSF is able to offer paid work at competitive rates to a small number of core contributors. We hope to be able to extend this offer to more core contributors in the future.

Zig Software Foundation Inc

ConnectMyVariant's mission is to end hereditary disease by bringing families together.

ConnectMyVariant is an educational health-focused 501(c)3 nonprofit organization that supports individuals and families with hereditary disease in their early detection and prevention efforts. We provide unique value by leveraging our evidenced-based family connection protocols to help people identify other at-risk relatives and help those relatives access genetic testing so that they can get optimal medical care. ConnectMyVariant brings people with the same genetic risk together through our variant database and community engagement events to share experiences and find common ancestors. ConnectMyVariant also works to increase awareness of the benefits of family outreach among physicians, others who provide prevention care, and the broader genealogy community.
 
Our key activities are:

- Working with patients to implement personalized family outreach plans
- Interactive educational workshops about sharing information on inherited disease risk
- Variant specific family reunions to share stories and plan outreach to cousins
- Genealogy assistance to help connect individuals in variant groups
- Individual equity and inclusion grants for family and community outreach

Need and Impact:
When hereditary disease risk is known, family outreach has been proven to be the most effective and cost-effective intervention for early detection and prevention. This family outreach, also known as cascade testing, is recommended by multiple guidelines. Despite overwhelming evidence, family outreach assistance is not reimbursed by insurance or integrated into healthcare. Many people suffer and die from hereditary disease that could have been prevented or caught early.
 
We have shown that our strategies to encourage family outreach can act as a communication multiplier. Our pilot research at the University of Washington showed that this approach enhanced patient experience, was considered ethical, and was appreciated by newly identified relatives. Our approach is low-cost and is 25 to 50 times more effective than awareness and education interventions that target the general population.

Equity and Inclusion:
ConnectMyVariant is committed to being a leader for equity, diversity, and inclusion in hereditary disease prevention. ConnectMyVariant’s goal is to spread awareness among all individuals and families about inherited disease risk. All project staff, participants, and partners in ConnectMyVariant have an equal voice in developing innovative ways to improve hereditary disease outreach and prevention for all people. By fostering a diverse and inclusive community, we can provide knowledge and opportunities that have been historically inaccessible to millions of people.

ConnectMyVariant

One of the oldest universities in the Netherlands and one of the largest in Europe. 

Established March 26, 1636, **Utrecht University** is one of the oldest universities in the Netherlands and one of the largest in Europe.  Utrecht University invests in educating the leaders of the future, offering high-quality, innovative education, with a high student pass rate. In the Netherlands, Utrecht University is a pioneer in innovative educational concepts, such as that of the University College. The University conducts fundamental and applied research in a wide range of disciplines. Multidisciplinary research in Utrecht focuses on four strategic themes: Dynamics of Youth, Institutions for Open Societies, Life Sciences and Pathways to Sustainability. 

**Utrecht University Fund** was founded in 1886, making it the Netherlands' oldest University Fund. It has has become a well-known name in the Utrecht University community and has always been a place for students, employees and alumni to come together in support of a flourishing academic climate in Utrecht. We strongly believe that generations can help each other.

**Mission** 
Sustaining innovative science requires investment. Funds are needed to invest in housing, laboratories, equipment, but most of all in people, i.e. students, lecturers and researchers from all over the world. Fortunately, over the centuries, Utrecht University has always been able to rely on the support of its alumni and others committed to the university. 

**Goals**
Utrecht University Fund supports student activities and is able to cater to the special requirements of science and education in areas where government funding is not available. Furthermore it aims to create awareness and involvement among students, university staff, alumni and the city of Utrecht in order to realize projects that help Utrecht University to grow and flourish. 

**Tax benefits**
The Utrecht University Fund is acknowledged as a so-called Public Benefit Organization (PBO/ANBI) exempting it from inheritance or gift tax. That means that all funds you donate are forwarded to your preferred cause. 
 
Be generous for the next generation. Give back to your university. Help Utrecht University grow and flourish in the areas of education, research and the living environment. 

Utrecht University and Utrecht University Fund 

This Fund advances fundamental science, supports scientists in developing countries, and fosters global collaboration at the ICTP.

**"Scientific thought and its creation is a common heritage of humankind"**                                                                                        -Abdus Salam, Founding Director, ICTP

The International Science Fund supports::

- **Scientific Excellence** Conduct world-class, pioneering research in frontier areas of science.
- **Global Inclusion** Make advanced science globally available to bridge the knowledge divide.
- **International Cooperation** Build international partnerships for and through science.                                                                     

The International Science Fund's support of ICTP combines excellence in research with a unique global [mission](https://www.ictp.it/home/our-mission) for international cooperation through science. 

Visit ICTP's [impact page](https://www.ictp.it/home/impact) to see and hear firsthand stories from past ICTP participants.

No donation is too small to make a difference. The International Science Fund supports ICTP's community which extends far and wide and we invite that community to join us in these efforts. By contributing to this Fund, you support not only a world-class research and education centre, but also the sustainable development of humanity.

The International Science Fund

CETI is a nonprofit org applying advanced machine learning and gentle robotics to listen to and translate whale communication. 

Founded in 2020 as a TED Audacious Project, the organization’s science team is made up of the world's leading artificial intelligence and natural language processing experts, marine biologists, cryptographers, linguists, roboticists and underwater acousticians. CETI’s research is taking place off of the island of Dominica in the Caribbean.

In the late 1960s, scientists, including Dr. Roger Payne, a principal advisor of CETI, discovered that whales sing to one another. His recordings, Songs of the Humpback Whale, sparked the “Save the Whales” movement, one of the most successful conservation initiatives in history. The campaign eventually led to the Marine Mammal Protection Act that marked the end of large-scale whaling and saved several whale populations from extinction. 

All this by just hearing the sounds of whales. Imagine what would happen if we could understand them?

WHY WHALES 
Sperm whales specifically share traits strikingly similar to humans. They live in matriarchal and multicultural societies and share dialects and strong multigenerational family bonds. Sperm whales have the largest brains of any species and have higher-level functions such as conscious thought and future planning, as well as speech and feelings of compassion, love, suffering and intuition. Their vocalizations, among the loudest animal sounds on the planet, have a Morse code-like structure that shares the hallmarks of a highly-evolved language. Our understanding of these animals and their dialects is still in its infancy. Only in the last fifteen years have we begun to learn how some of their vocalizations are used for communication.  
WHAT CETI IS DOING
CETI is:
-Developing non-invasive robotics to listen to a population of whales in the Caribbean and put their sounds into context.
-Deploying a “Core Whale Listening System,” an innovative hydrophone array, underwater robotic gliders, custom bioinspired whale tags and other technology to gently study the whales.
-Building on substantial data on the whales’ sounds, social lives, and behavior already obtained by the Dominica Sperm Whale Project. 
-Creating a bespoke, big-data pipeline to examine the recorded data and decode it using advanced machine learning, natural language processing and data science.
-Publishing a series of academic papers beginning with the CETI roadmap.
-Collaborating with the National Geographic Society, including their Exploration Technology Lab, and amplifying the project across National Geographic’s storytelling and education channels.
-Implementing community-based programs like the Dominica Marine Conservation Fellowship, a community-based 10-month multi- module training program for young Dominicans interested in marine science, that was developed in partnership with National Geographic.
-Launching various communications projects to tell CETI’s story including a public interface for the citizen science community, resources for educators and children and arts programs.

IMPACT
Now, for the first time in history, it’s possible to use artificial intelligence to identify and interpret deep structure within animal communication. Using these technologies, CETI is building on the legacy of the “Save the Whales” movement with the goal of having an impact by contributing the following:
Interspecies Communication - A new data set of unprecedented size to the rapidly expanding field of interspecies communication and a roadmap of how humans could translate the communication of any other species
Marine Biology - A substantive contribution to the field of whale research within marine biology that opens gateways for future research initiatives. 
Policy - New information about whales that can bolster policy efforts to protect marine mammals and ocean habitats. Policy advances in this area are crucial as six out of the 13 “great” whale species (the largest whales) are still endangered (World Wildlife Federation). To ensure impact in this area, CETI plans to build out policy campaigns and initiatives. 
Perspective - It is widely endorsed that connectivity with nature can improve mental health. By sharing its journey and findings with the public, CETI hopes to contribute to a feeling of increased wonder and connectedness to whales and the ocean that can inspire action. CETI will build out arts and childrens’ initiatives in support of this impact goal.
Conservation - CETI’s first phase of research is taking place in Dominica in the Caribbean, a region that is one of the world’s greatest centers of diversity. By carrying out its research in partnership with local stakeholders, CETI hopes to contribute to regionally-led research and conservation efforts.

HOW CETI IS SUPPORTING DOMINICA
-CETI’s capacity-building initiative, Dominica Marine Conservation Fellowship is a 10-month, nine module training program for young Dominicans interested in marine science) in partnership with National Geographic.  The program has three 2022/2023 fellows and partnerships with the Dominica National Youth Council, Dominica State College and Dominica’s Ministry of Education. The program’s curriculum (co-created with National Geographic) includes modules on marine science, scientific research/techniques, water and vessel skills and storytelling and leadership among other topics.
-All research and findings by CETI in Dominica are all open-source and will be available for Dominica. The organization’s sailing research vessel (CETI-1), a Rigid Inflatable Boat (CETI-2) and Dominican made boat (CETI-3) are in operation in Dominican waters; these boats along with other CETI equipment will be donated to the local entity at the completion of the project.
-A temporary field station has been established in Dominica and has the capacity to host 10-12 researchers, fellows and students. In the long-term, CETI plans to build a permanent field station in Dominica 
-In 2023, CETI will continue local engagement and presentations with primary and secondary schools, development of video content for use in classrooms, collaborations with local artists and collaborations with local stakeholders such as marine and dive operators, civil society organizations and schools.



Project CETI

Eliminating obstacles on the path to the comprehensive medical control of aging and age-related disease.

Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.

Longevity Escape Velocity Foundation

The Vision of the EWT is a healthy planet and an equitable world that values and sustains the diversity of all life.

The EWT is among South Africa’s largest and
most established national non-governmental
conservation organizations.  Founded in 1973, we are a non-profit organization with an expanding footprint
throughout southern and East Africa, focusing
on conserving threatened species and ecosystems to the benefit of people. We achieve this by conducting on-the-ground research, supporting community-led conservation, training and building capacity, addressing human-wildlife conflict, monitoring threatened species, and establishing safe spaces for wildlife range expansion.

The EWT works with key partners, including
communities, businesses, landowners, academic
institutions, and governments, to create a
sustainable future for wildlife and people.
 The Endangered Wildlife Trust is dedicated to
conserving threatened species and ecosystems in southern and East Africa to the benefit of all.

The EWT achieves this mission by delivering on
three strategic imperatives: Saving species,
conserving habitats, and benefiting people.
OUR STRATEGY
Our conservation programmes form the
organization’s backbone, harnessing the talent
and enthusiasm of a dynamic team of
individuals whose unique exper􀆟se and
mo􀆟va􀆟on provide them with the tools to
respond to the challenges they face in pursuit
of saving our most threatened species and
ecosystems.
The EWT is a registered Trust governed in accordance with the Trust Property Control Act No. 57 of 1988, under Master’s reference number IT 6247. The EWT is also registered in South Africa as a Non-Profit Organisation, registration number 015- 502 NPO
and Public Benefit Organisation, registration number 930 001 777

SPECIES RECOVERY
The EWT has achieved remarkable gains for many species, where downward trends in the local populations of Wattled and Grey Crowned Cranes, Piggersgill’s Frogs, the Amathole Toad, and the Riverine Rabbit have joined the Cheetah as species on a pathway to recovery. Critically Endangered
Wattled Cranes are increasing in number, now estimated at some 320 birds nationally, up 60% from their lowest numbers. The EWT has also helped reverse the decline of Endangered Grey Crowned Cranes, while Blue Crane numbers have increased from an estimated 25,500 birds nationally in 2007 to some 30,000 birds today.
SPACE FOR SPECIES
Through our range expansion work, we have secured and protected safe spaces for multiple species to thrive and we have reintroduced many threatened species back into secure and suitable landscapes. Safe space for African Wild Dogs has increased to over 1.4 million ha throughout southern Africa and their numbers and generic health have followed suit. Safe space for Cheetahs and their numbers have also increased from 217 Cheetahs on 41 reserves in South Africa in 2011, to 470 Cheetahs on 65 reserves covering over two million hectares across southern Africa.

SAFEGUARDING OUR SPECIES
To protect threatened species, we monitor them and work with partners, businesses, landowners, and communities to reduce the threats they face. We are innovating to achieve bigger impacts, as evident in our drone project’s expansion to use drones to mark power lines - reducing bird strikes safely and affordably and monitor Southern Right Whales in a way that wasn’t possible before. We continue to explore the use of eDNA to identify the presence of elusive and potentially extinct species, such as
Van Zyl’s and De Winton’s Golden Moles, so that action can be taken to save the last of their habitats.

Our pioneering Eye in the Sky carcass and wildlife poisoning detection project has already saved thousands of animals from secondary poisoning as a result of its efficient and effective success and our quick response times. The project uses the movements and behavior patterns of GPS-tracked vultures to remotely detect potential poisoning events and respond to these rapidly, alerting rangers on the ground and preventing further loss of wildlife to poisoning. We also contribute to preventing wildlife crime through the deployment of Conservation K9s to detect wildlife contraband and track poachers. These dogs help us to protect species, including rhinos, elephants, and pangolins.

Protec􀆟ng and conserving natural places is one of the most important strategies for comba􀆫ng the effects of
biodiversity loss and climate change. The EWT conserves habitats by reducing habitat loss and improving the
ecological integrity of threatened ecosystems through rehabilita􀆟on, restora􀆟on, and sustainable land
management. Many of the EWT’s programmes are involved in habitat conservation, but two are dedicated to protecting specific habitats.

COLLABORATING FOR CONSERVATION
An effective vehicle for conserving habitats is the formal protection of land through Biodiversity Stewardship. We work with private and community landowners to legally declare their land as protected or help them to manage it sustainably and without damage to sensitive species and ecosystems.
The EWT was instrumental in the development of Biodiversity Stewardship, having facilitated the workshops which led to its establishment, and subsequently, the EWT has declared 185 properties (over 139,000 ha) as protected areas in the last
ten years and is currently in the process of securing a further 130,000 hectares for threatened species conservation across South Africa. This includes proper􀆟es in one of the region’s most important centres of endemism: the Soutpansberg Mountain Range. Easily recognized for our work to safeguard charisma􀆟c species like the Wild Dog and Cheetah, the EWT also played a key role in preventing the extinction of the Brenton Blue Butterfly by establishing a dedicated reserve for this endemic insect.  Other critical habitats have been protected to prevent the extinction of many smaller, lesser-known species, including rep􀆟les, amphibians, butterflies, golden moles, and threatened plants.

CARBON FOR CONSERVATION
After establishing the feasibility of carbon trading in South Africa’s grasslands and recognizing the potential benefits for farmers and grassland and wetland management, the EWT the EWT initiated the first carbon offsetting contracts with private landowners in South Africa, in the Drakensberg.
When landowners agree to conserve and manage their land to allow for the verifiable sequestration of carbon in the soil, the carbon can be converted into carbon credits. Liable ensures, usually big carbon emitters, can purchase up to 10% of their carbon as carbon credits to reduce their tax liability in South Africa. These purchases create a long-term revenue stream for farmers and conservation organizations to support conservation efforts and protect important habitats through improved land-use management.

People need nature to survive – it provides important resources we depend on. We must live in harmony
with nature to thrive in healthy ecosystems that will support us and future genera􀆟ons, our wildlife, and
maintain our rich natural and cultural heritage. Through two of its programmes, the EWT implements
innovative strategies that incorporate the needs of people and the environment to ensure that people
benefit from the more sustainable use of natural resources.
BENEFITTING PEOPLE
CAPACITY FOR CONSERVATION
Working across diverse landscapes such as wetlands,
grasslands, river catchments, savannahs, and mountains, the EWT has embraced the need to support the lives and livelihoods of thousands of people who depend on their local environment, from developing sustainable livelihoods as alternatives to environmentally destructive practices in communities from KwaZulu-Natal to Limpopo, Zambia, and as far as Uganda, to pioneering the implementation of Population, Health and Environment in communities in southern and East Africa to support sustainable communities and empower women. The EWT
promotes and implements the education of school
learners and builds capacity for conservation and
ecotourism in communities across our project areas.

BIODIVERSITY AND BUSINESS
Recognizing the importance of biodiversity to business, the EWT established the National Biodiversity and Business Network (NBBN) in 2013 to work with innovative businesses to identify and manage the risks and opportunities resulting from their interactions with the natural world. Through its Biodiversity Disclosure Project, the NBBN helps companies to understand, measure, and disclose their biodiversity impacts and policies. The NBBN introduced the world’s first standardized accounting
framework, the Biological Diversity Protocol (BDP), which measures a business’ impact on biodiversity and identifies areas of improvement over time.  The EWT’s targeted conservation work has national and global impacts and our achievements contribute to multiple conservation-related frameworks. These include South Africa’s 2nd National Biodiversity Strategy and Action Plan (2015–2025), and the National Biodiversity Assessment which assess the status of, and identify the biodiversity and ecosystem
management priori􀆟es as well as the International Union for Conservation of Nature (IUCN) Red List of Threatened Species. 

Arguably, the EWT’s most important global impact is our work toward achieving the Sustainable Development Goals (SDGs), a collection of 17 interlinked global goals designed by the United Nations. The SDGs are a universal set of goals, targets, and indicators that UN member states should use to frame their agendas and political policies. Ambitious by nature, they are a government-led endeavor that serves to coordinate actions by United Nations agencies, businesses, non-governmental groups, and any other entities working on specific goals. These are
the goals that the EWT contributes to.



Endangered Wildlife Trust

The AI Futures Project is a nonprofit research organization working to research and understand the trajectory of AI development

The **AI Futures Project** is a 501(c)(3) nonprofit research organization. We have developed a scenario forecast detailing the development of artificial general intelligence (AGI) and artificial superintelligence (ASI). Based on our research, we’ve come to believe that we might cross the thresholds to AGI and ASI within just a few years—and that plausible outcomes include unprecedented concentration of power, global catastrophe, or progress and flourishing.

The world is not ready for such a radical transformation. We hope to help policymakers, AI companies, AI entrepreneurs, AI safety researchers, and the general public to make sense of what’s coming, so they can take action and steer us in a better direction. In addition to our scenario forecast, we are developing [policy recommendations](https://time.com/collection/time100-voices/7086285/ai-transparency-measures/) and tabletop exercises (wargames) for decisionmakers.



AI Futures Project

Supporting research on the welfare of neglected animals.

There are millions of known arthropod species. There are doubtless millions more. And there may be quintillions of individual arthropods.

We know little about most of these animals and, as a result, little about how their welfare might be improved in contexts where humans use, manage, or otherwise affect them.

The mission of the Arthropoda Foundation is to support research on the welfare of arthropods. We value both basic and applied projects. We are particularly interested in research with a clear path to impact, whether by shaping future science or informing real-world decision-making.

Arthropoda Foundation

MAPS works towards a post-prohibition world by advancing research, changing policies, and shaping culture. 

Since our founding in 1986, the Multidisciplinary Association for Psychedelic Studies (MAPS) has been the leading organization building the movement to foster evidence-based approaches to psychedelics and the people who use them. When used safely and responsibly, psychedelics have the potential to promote personal growth and well-being and treat various mental health conditions. Three pillars guide our efforts: advancing research, changing policies, and shaping culture. 

[Advancing Research](https://maps.org/advancing-research/)

MAPS spent decades developing MDMA-assisted therapy for the clinical utilization of psychedelic-assisted therapies. With the road paved for the next generation of research and drug development, MAPS now stewards the research landscape we helped cultivate.

We are dedicated to fostering new research directions that prioritize public benefit, supporting international researchers and pilot programs, and ensuring the accessibility and culturally appropriate integration of psychedelics as a tool for individual and community wellness. We center research that contributes to knowledge in the public domain.

[Changing Policy](https://maps.org/changing-policy/)

The cultivation, use, and trade of psychoactive substances — including psychedelics — has been a consistent aspect of human history, but prohibition, criminalization, and militarization — and their inherent oppression — have led to drastic consequences. The ongoing, global War on Drugs has been justified by bad science, racism, and fear for too long: it has led to mass incarceration; erosion of civil liberties; ecological damage; economic waste; and the public health polycrisis of adulteration, poisoning, and overdose. Many of these harmful effects have disproportionately impacted the most historically exploited and oppressed communities. Consequently, we believe societies worldwide have an obligation to account for and repair those harms, to the extent possible. 

MAPS envisions a post-prohibition future based on Consciousness, not Criminalization.

[Shaping Culture](https://maps.org/shaping-culture/)

For psychedelics to be most safely integrated into society, we need to be honest about the implications. MAPS recognizes the importance of a comprehensive understanding of their risks and potential benefits, teaching people how to navigate altered states of consciousness and how policies impact individuals and communities. 

We create cutting-edge education for professionals and the public, provide expert support for the psychedelic and drug policy movement, and convene people who share our vision—all to lay the groundwork and create the guardrails necessary for responsible social transformation. 

As psychedelics become more mainstream and an increasing number of people seek to use them for healing and personal growth, we are more dedicated than ever to making resources available for people and communities to safely and responsibly integrate psychedelics into medical, legal, and spiritual contexts.

MAPS

IBB equips individuals across the Middle East with the information, skills, and resources to build a free &more prosperous future


We partner with people across the region to make vital and often banned information accessible in Arabic, Dari, Pashto and Kurdish. We certify each of our translators to produce and distribute content on topics like critical thinking, civil rights, science, and pluralism. We also place trust and resources into the hands of people across MENA who are forging sustainable paths to prosperity through entrepreneurship.




Ideas Beyond Borders

We defend your civil liberties in a digital world.

The first line of defense when your rights in the digital world come under attack. EFF champions user privacy, free expression, and innovation through impact litigation, policy analysis, grassroots activism, and technology development. We work to ensure that rights and freedoms are enhanced and protected as our use of technology grows.

Electronic Frontier Foundation (EFF)

Delivering unconditional cash directly to the world's poorest households via secure mobile transfers. 

Since 2009, GiveDirectly has delivered more than $580 million in unconditional cash transfers to families in need. These one-time cash transfers allow recipients to invest in what they need most and have been shown to improve their earnings, children’s school attendance, health, nutrition, and mental well-being.
 
GiveDirectly uses government data to target villages where most or all residents are living in extreme poverty, defined by the World Bank as earning under $2.15/day. In-country GiveDirectly staff enroll one member of each household in the entire village to receive a one-time transfer of about $1,000 USD sent in two installments using mobile money. Recipients can then withdraw the mobile funds as cash with local agents and use the funds to invest in what they need – whether it’s on starting a business, education, making their home safer/sturdier, healthcare, or livestock.
 
GiveDirectly uses rigorous experimental research (randomized controlled trials) to measure the impact of their unconditional cash programs and answer public policy questions, generating evidence on key design and implementation questions across varied contexts. You can find over 300 studies on the positive impacts of cash transfers in GiveDirectly’s Cash Research Explorer.

GiveDirectly

Protecting free expression and enabling secure global communication through open source privacy technology.

Long before we knew that it would be called Signal, we knew what we wanted it to be. Instead of teaching the rest of the world cryptography, we wanted to see if we could develop cryptography that worked for the rest of the world. At the time, the industry consensus was largely that encryption and cryptography would remain unusable, but we started Signal with the idea that private communication could be simple.

Since then, we’ve made some progress. We’ve built a service used by millions, and software used by billions. The stories that make it back to us and keep us going are the stories of people discovering each other in moments where they found they could speak freely over Signal, of people falling in love over Signal, of people organizing ambitious plans over Signal. When we ask friends who at their workplace is on Signal and they respond “every C-level executive, and the kitchen staff.” When we receive a subpoena for user data and have nothing to send back but a blank sheet of paper. When we catch that glimpse of “Signal blue” on a metro commuter’s phone and smile.

However, we’ve always wanted to do much more, and our limitations have often been challenging. Over the lifetime of the project, there have only been an average of 2.3 full-time software developers, and the entire Signal team has never been more than 7 people. With three client platforms to develop, a service to build and run, a growing list of integrations to assist with, and millions of users to support, that has often left us wanting.

Even so, Signal has never taken VC funding or sought investment, because we felt that putting profit first would be incompatible with building a sustainable project that put users first. As a consequence, Signal has sometimes suffered from our lack of resources or capacity in the short term, but we’ve always felt those values would lead to the best possible experience in the long term. The Signal Foundation completes our vision of Signal operating as part of a full 501(c)(3).

Signal Technology Foundation

Terra Praxis designs and implements strategies that leverage science, technology and energy innovation for a prosperous planet

We co-founded TerraPraxis to design and implement strategies that leverage science, technology and energy innovation for a prosperous planet. Our mission is to innovate and accelerate scalable, equitable solutions for unsolved areas of the climate challenge. 

Our special focus is on enabling high-impact rapid transitions for neglected parts of the decarbonization challenge. 

We work with an extensive global network to define, incubate and initiate scalable strategies that fulfil the twin missions of prosperity and decarbonization. 

Terra Praxis

ARC is a non-profit research organization whose mission is to align future machine learning systems with human interests. 

See our website for more info about our work. 

Alignment Research Center

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.

GiveWell

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We are a nonprofit, so we rely on the generosity of donors like you.

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Mersal Foundation for Charity and Development

Mersal Foundation for Charity and Development

Timothy Seminaries International

Mersal Foundation for Charity and Development

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