Aubrey and his teams have a history of making biorejuvenation breakthroughs that lay the groundwork for future anti-aging therapies that will someday save billions of lives. They tackle the intractable bits of aging, bits that are too speculative or longterm or unprofitable for venture capital. I’m proud to support LEVF and Aubrey and their work to defeat aging.

Eliminating obstacles on the path to the comprehensive medical control of aging and age-related disease.

Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.

Longevity Escape Velocity Foundation

We match donations to any charity you choose while introducing you to super-effective charities. Learn more: GivingMultiplier.org

[**Giving Multiplier**](https://givingmultiplier.org) is a research project created at Harvard University that adds matching funds to any charity of your choice while introducing donors to highly effective charities recommended by experts.

*Resources:*

- [Make a donation that gets matched](https://givingmultiplier.org)
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Questions? Email us: **info@givingmultiplier.org**

Giving Multiplier

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

The Karman Project unites leaders from 70+ nations to promote peaceful, sustainable space tech for humanity’s benefit.

With its enabling technologies and inherently international environment, space is uniquely positioned to aid humanity in responding to and solving some of the most time-critical challenges that we face on Earth. With various satellite and Earth-observation technologies providing us with real-time data of our home planet, we’re empowered to map, understand - and more importantly, mitigate - everything from wildfires to deforestation to illegal fishing, whilst improving things like supply chain efficiency, agricultural practices and disaster management coordination. In parallel, there is significant commercial competition emerging from key players in space, particularly with respect to space exploration and the use of space resources. Ensuring the cooperative and responsible use of space and its technologies at a global scale is essential to our collective future - and herein lies the core mission of The Karman Project. 

The Karman Project is an award-winning non-profit foundation uniting global decision-makers to drive urgent, collaborative action for a sustainable and peaceful future in space. With the space domain becoming increasingly vital to addressing humanity’s most urgent challenges – from climate monitoring and disaster management to global communications and the future of health – we’re working to safeguard space for generations to come.

We run high-impact programs that accelerate the work of exceptional space leaders and organisations. This curated and diverse community includes high-level leaders from more than 70 nations, from astronauts to agency heads, industry executives, researchers, and artists.

Our flagship Fellowship and Pioneer Programs focus on three pillars: Leadership, Dialogue and Action. Fellows build trust, exchange ideas, and drive forward collaborative projects across six key themes: Sustainability, Education, Empowerment, Cooperation, Science, and Inspiration. These programs are supported by global events and partnerships with trusted institutions such as the University of Oxford, Blue Origin’s Club for the Future, and King Charles’ Sustainable Markets Initiative.

The Karman Project has supported the development of over 80 capacity-building projects around the world (aligned with the United Nations Sustainable Development Goals), directly improving the lives of more than 5 million people and delivering an estimated 8.8x social return on investment. We’ve awarded 90 scholarships to high-impact leaders, hosted delegations in 10+ countries, and contributed to space policy at the United Nations level.

In an effort to incentivise macro-level changes in space, The Karman Project is currently launching the Space Peace Prize™ with the support of Founding Partners to recognise and elevate extraordinary contributions to international cooperation in space. It aims to stand as the foremost international recognition for projects advancing peace and sustainability in space, and accelerate strategic engagements across the sector during a time marked with global uncertainty. 

Karman Project

The Deep Space Exploration Society is a nonprofit organization dedicated to space science  education for underserved communities. 

The Deep Space Exploration Society is a Colorado-based nonprofit organization and charity dedicated to practical astronomy and space science education for students, the general public, and society members.

Our major project is restoring and operating a 60-foot dish antenna for radio astronomy and amateur radio experimenting.  The site is located in Kiowa County, Colorado. Since 2009, our volunteer members have been working hard to restore and modernize the antenna and its support facilities.  Additionally, we support radio astronomy and amateur radio projects using smaller antennas.  We also support educational outreach and support the local community by fund raising at our annual Open House.

The Deep Space Exploration Society

Extending and improving the lives of people with ALK+ lung cancer by raising funds for research and patient support programs.

**Our Vision**

We envision a world where ALK+ lung cancer is a chronic or even curable condition and the next person diagnosed with lung cancer does not have to live under the current stigma.

**Our Start**

\#SweatForBreath started as a grassroots fundraising campaign during Lung Cancer Awareness Month in 2023. After being diagnosed with Stage IV ALK+ lung cancer in November 2022, David Cornbrooks became keenly aware that he was benefiting from the selfless fundraising and awareness efforts of the patients before him.

[Listen to David's story here.](https://www.youtube.com/watch?v=lWcS-yN7Qxw)

The \#SweatForBreath campaign in 2023 became David, and his wife, Lisa’s, way to help the next generation ALK+ lung cancer patients.

\#SweatForBreath accelerated beyond more than just a typical fundraiser.  The initiative quickly evolved into a community of patients, caregivers, family, and friends seeking to make David and Lisa's vision a reality and the road to that vision more tolerable. People donated, sweat at the in-person cycle event, posted on social media, and helped fundraise through organizing group walks, selling art, "gifting" donations on behalf of clients, and much more.

Their success in 2023 compelled David and Lisa to officially transition the \#SweatForBreath campaign into the Sweat For Breath Foundation, operating through a fiscal sponsorship with Players Philanthropy Fund, a Maryland charitable trust recognized by IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178).

**Our Impact**

Since 2023, over **1,450 donors** have given nearly **$400,000** to the Foundation (or its predecessor campaign). 100% of the proceeds have gone directly to The Johns Hopkins Sidney Kimmel Center in Baltimore, MD to support Dr. Vincent Lam’s ALK+ lung cancer research.

This support provided the critical funding needed to launch Dr. Lam’s clinic trial, which will evaluate the safety of a cancer peptide vaccine to prevent or delay acquired resistance in advanced ALK+ lung cancer patients currently on ALK targeted therapy. Dr. Lam’s vaccine is the **first ALK+ vaccine in the world** to be tested in a clinical trial. Dr. Lam administered the vaccine to the first patient **in clinic on May 13, 2024**!

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*The Sweat for Breath Foundation is a project of Players Philanthropy Fund, Inc. a Texas nonprofit corporation recognized by IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178,[ppf.org/pp](https://ppf.org/pp)). Contributions to The Sweat for Breath Foundation qualify as tax-deductible to the fullest extent of the law.*


The Sweat For Breath Foundation

Supporting research on the welfare of neglected animals.

There are millions of known arthropod species. There are doubtless millions more. And there may be quintillions of individual arthropods.

We know little about most of these animals and, as a result, little about how their welfare might be improved in contexts where humans use, manage, or otherwise affect them.

The mission of the Arthropoda Foundation is to support research on the welfare of arthropods. We value both basic and applied projects. We are particularly interested in research with a clear path to impact, whether by shaping future science or informing real-world decision-making.

Arthropoda Foundation

Zig is a general-purpose programming language and toolchain for maintaining robust, optimal, and reusable software.

The Zig Software Foundation is a non-profit corporation founded in 2020 by Andrew Kelley, the creator of Zig, with the goal of supporting the development of the language. Currently, the ZSF is able to offer paid work at competitive rates to a small number of core contributors. We hope to be able to extend this offer to more core contributors in the future.

Zig Software Foundation Inc

A research nonprofit that works on assessing whether cutting-edge AI systems could pose catastrophic risks to society.

METR (Model Evaluation and Threat Research) builds the science of accurately assessing risks, so that humanity is informed before developing transformative AI systems.

We believe that AI could change the world quickly and drastically, with potential for both enormous good and enormous harm. We also believe it’s hard to predict exactly when and how this might happen.

At some point, AIs will probably be able to do most of what humans can do, including developing new technologies; starting businesses and making money; finding new cybersecurity exploits and fixes; and more.

We think it’s very plausible that AI systems could end up pursuing goals that are at odds with a thriving civilization. This could be due to someone’s deliberate effort to cause chaos, or happen despite the intention to only develop AI systems that are safe.

Given how quickly things could play out, we don’t think it’s good enough to “wait and see” whether there are dangers.

We believe in vigilantly, continually assessing risks. If an AI brings significant risk of a global catastrophe, the decision to develop and/or release it can’t lie only with the company that creates it.

METR

Terra Praxis designs and implements strategies that leverage science, technology and energy innovation for a prosperous planet

We co-founded TerraPraxis to design and implement strategies that leverage science, technology and energy innovation for a prosperous planet. Our mission is to innovate and accelerate scalable, equitable solutions for unsolved areas of the climate challenge. 

Our special focus is on enabling high-impact rapid transitions for neglected parts of the decarbonization challenge. 

We work with an extensive global network to define, incubate and initiate scalable strategies that fulfil the twin missions of prosperity and decarbonization. 

Terra Praxis

Spritely Institute builds, researches, and standardizes networked technology which put people and communities first.


Centralized social media is harmful to society. We are building a gatekeeper-free decentralized system. Our mission is “social media done right”, to put people in control of their own identity and build the technology that would enable a shift to collaborative and intentional security models prioritizing active consent. To accomplish this, we will build a new architecture for the internet: removing the necessity of client-server architecture, replacing it with a participatory peer-centric model.

Spritely’s technology is being released as free and open source software aiming for multiple programming language implementations and eventual open standardization. All of our work, ranging from decentralized identity, peer-to-peer user agents, decentralized social networks, encrypted and portable storage, and distributed object programming infrastructure is being built to enable a gatekeeper-free path where users and content are not tied to a specific server.

Spritely Networked Communities Institute

The IWM is a non-profit institution that promotes intellectual work and enables encounters of people around ideas. 

The Institute for Human Sciences (IWM Vienna) is an institute of advanced studies in the humanities and social sciences founded in 1982. We promote intellectual exchange across disciplines, between academia and society, and among regions that now embrace Eastern, Central and Western Europe, the Global South and North. We aim to reframe larger questions of academic debate and public interest that address today's complex challenges. We believe that sustained intellectual work and its broad dissemination is essential to a humane future of open, just, and sustainable societies. 

Institut für die Wissenschaften vom Menschen (IWM)

Animal Charity Evaluators helps people help the most animals.

Do you want to help animals but find it hard to decide how? That's understandable. Trillions of animals suffer every day on farms and in the wild. The problem is vast and complex, but people around the world are making a difference.

Animal Charity Evaluators (ACE) is a 501(c)(3) nonprofit registered in the United States dedicated to finding and promoting the most effective ways to help animals. We do this by evaluating and recommending high-impact charities, awarding strategic grants to promising projects, and raising critical funds for the animal advocacy movement. Our ultimate goal is to educate and empower individuals and organizations to make a significant and lasting positive impact on the lives of neglected animals who are often forgotten. ACE envisions a future in which no individual is given less than full moral consideration on the basis of any morally irrelevant feature of their identity, including species membership.

ACE has a unique and influential role within the effective animal advocacy movement. Our global team is composed of experienced professionals in animal advocacy, effective altruism, and research methodology. To date, we have rigorously evaluated 85 charities that work to end factory farming and create meaningful change for farmed and wild animals, and recommended 38 high-impact organizations as effective giving opportunities. Through our strategic grantmaking, we have distributed nearly $20 million to our Recommended Charities and promising advocacy projects around the globe. Since ACE began tracking this metric in 2014, we estimate that we’ve helped to influence at least $81 million within the animal advocacy movement. Over the years, we have built strong partnerships with organizations and researchers, amplifying our collective efforts to improve the lives of as many animals as possible. 

Join us! Together, we can build a future that's kind to *all* species.

Animal Charity Evaluators

CETI is a nonprofit org applying advanced machine learning and gentle robotics to listen to and translate whale communication. 

Founded in 2020 as a TED Audacious Project, the organization’s science team is made up of the world's leading artificial intelligence and natural language processing experts, marine biologists, cryptographers, linguists, roboticists and underwater acousticians. CETI’s research is taking place off of the island of Dominica in the Caribbean.

In the late 1960s, scientists, including Dr. Roger Payne, a principal advisor of CETI, discovered that whales sing to one another. His recordings, Songs of the Humpback Whale, sparked the “Save the Whales” movement, one of the most successful conservation initiatives in history. The campaign eventually led to the Marine Mammal Protection Act that marked the end of large-scale whaling and saved several whale populations from extinction. 

All this by just hearing the sounds of whales. Imagine what would happen if we could understand them?

WHY WHALES 
Sperm whales specifically share traits strikingly similar to humans. They live in matriarchal and multicultural societies and share dialects and strong multigenerational family bonds. Sperm whales have the largest brains of any species and have higher-level functions such as conscious thought and future planning, as well as speech and feelings of compassion, love, suffering and intuition. Their vocalizations, among the loudest animal sounds on the planet, have a Morse code-like structure that shares the hallmarks of a highly-evolved language. Our understanding of these animals and their dialects is still in its infancy. Only in the last fifteen years have we begun to learn how some of their vocalizations are used for communication.  
WHAT CETI IS DOING
CETI is:
-Developing non-invasive robotics to listen to a population of whales in the Caribbean and put their sounds into context.
-Deploying a “Core Whale Listening System,” an innovative hydrophone array, underwater robotic gliders, custom bioinspired whale tags and other technology to gently study the whales.
-Building on substantial data on the whales’ sounds, social lives, and behavior already obtained by the Dominica Sperm Whale Project. 
-Creating a bespoke, big-data pipeline to examine the recorded data and decode it using advanced machine learning, natural language processing and data science.
-Publishing a series of academic papers beginning with the CETI roadmap.
-Collaborating with the National Geographic Society, including their Exploration Technology Lab, and amplifying the project across National Geographic’s storytelling and education channels.
-Implementing community-based programs like the Dominica Marine Conservation Fellowship, a community-based 10-month multi- module training program for young Dominicans interested in marine science, that was developed in partnership with National Geographic.
-Launching various communications projects to tell CETI’s story including a public interface for the citizen science community, resources for educators and children and arts programs.

IMPACT
Now, for the first time in history, it’s possible to use artificial intelligence to identify and interpret deep structure within animal communication. Using these technologies, CETI is building on the legacy of the “Save the Whales” movement with the goal of having an impact by contributing the following:
Interspecies Communication - A new data set of unprecedented size to the rapidly expanding field of interspecies communication and a roadmap of how humans could translate the communication of any other species
Marine Biology - A substantive contribution to the field of whale research within marine biology that opens gateways for future research initiatives. 
Policy - New information about whales that can bolster policy efforts to protect marine mammals and ocean habitats. Policy advances in this area are crucial as six out of the 13 “great” whale species (the largest whales) are still endangered (World Wildlife Federation). To ensure impact in this area, CETI plans to build out policy campaigns and initiatives. 
Perspective - It is widely endorsed that connectivity with nature can improve mental health. By sharing its journey and findings with the public, CETI hopes to contribute to a feeling of increased wonder and connectedness to whales and the ocean that can inspire action. CETI will build out arts and childrens’ initiatives in support of this impact goal.
Conservation - CETI’s first phase of research is taking place in Dominica in the Caribbean, a region that is one of the world’s greatest centers of diversity. By carrying out its research in partnership with local stakeholders, CETI hopes to contribute to regionally-led research and conservation efforts.

HOW CETI IS SUPPORTING DOMINICA
-CETI’s capacity-building initiative, Dominica Marine Conservation Fellowship is a 10-month, nine module training program for young Dominicans interested in marine science) in partnership with National Geographic.  The program has three 2022/2023 fellows and partnerships with the Dominica National Youth Council, Dominica State College and Dominica’s Ministry of Education. The program’s curriculum (co-created with National Geographic) includes modules on marine science, scientific research/techniques, water and vessel skills and storytelling and leadership among other topics.
-All research and findings by CETI in Dominica are all open-source and will be available for Dominica. The organization’s sailing research vessel (CETI-1), a Rigid Inflatable Boat (CETI-2) and Dominican made boat (CETI-3) are in operation in Dominican waters; these boats along with other CETI equipment will be donated to the local entity at the completion of the project.
-A temporary field station has been established in Dominica and has the capacity to host 10-12 researchers, fellows and students. In the long-term, CETI plans to build a permanent field station in Dominica 
-In 2023, CETI will continue local engagement and presentations with primary and secondary schools, development of video content for use in classrooms, collaborations with local artists and collaborations with local stakeholders such as marine and dive operators, civil society organizations and schools.



Project CETI

We defend your civil liberties in a digital world.

The first line of defense when your rights in the digital world come under attack. EFF champions user privacy, free expression, and innovation through impact litigation, policy analysis, grassroots activism, and technology development. We work to ensure that rights and freedoms are enhanced and protected as our use of technology grows.

Electronic Frontier Foundation (EFF)

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We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

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Longevity Escape Velocity Foundation

Karman Project

Giving Multiplier

Mersal Foundation for Charity and Development

Mersal Foundation for Charity and Development

Giving Multiplier

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