I gave because I believe that we are all responsible for each other. As a privileged person you have to share with ones who are not the same lucky as you are.

The lives and health of our parents depends on us taking advantage of the new abilities of AI and science to keep them healthy and active.  We need to educate the public of the new reality and new possibilities for harnessing the wisdom and experience that comes with time... helping it be exercised from a place of health and vitality!  I'm doing this for my mom and dad!

GO GO GO GUYS !! Super proud of you both, what a wild and demanding adventure, best of luck 💪

I gave because I have really enjoyed learning zig and would love to see the language continue to evolve independently.

Delivering unconditional cash directly to the world's poorest households via secure mobile transfers. 

Since 2009, GiveDirectly has delivered more than $580 million in unconditional cash transfers to families in need. These one-time cash transfers allow recipients to invest in what they need most and have been shown to improve their earnings, children’s school attendance, health, nutrition, and mental well-being.
 
GiveDirectly uses government data to target villages where most or all residents are living in extreme poverty, defined by the World Bank as earning under $2.15/day. In-country GiveDirectly staff enroll one member of each household in the entire village to receive a one-time transfer of about $1,000 USD sent in two installments using mobile money. Recipients can then withdraw the mobile funds as cash with local agents and use the funds to invest in what they need – whether it’s on starting a business, education, making their home safer/sturdier, healthcare, or livestock.
 
GiveDirectly uses rigorous experimental research (randomized controlled trials) to measure the impact of their unconditional cash programs and answer public policy questions, generating evidence on key design and implementation questions across varied contexts. You can find over 300 studies on the positive impacts of cash transfers in GiveDirectly’s Cash Research Explorer.

GiveDirectly

Inspiring a Cultural Change to Transform Human Health

**ALSAE'**s (pronounced "All Say") is a nonprofit foundation whose mission is to unite longevity science and the arts through collaborations with creators and scientists, inspiring cultural change and accelerating progress in curing age-related diseases—such as Alzheimer’s, cardiovascular disease, and cancer—ensuring everyone can enjoy longer, healthier lives.

Alliance for Longevity Science, Arts & Entertainment

Zig is a general-purpose programming language and toolchain for maintaining robust, optimal, and reusable software.

The Zig Software Foundation is a non-profit corporation founded in 2020 by Andrew Kelley, the creator of Zig, with the goal of supporting the development of the language. Currently, the ZSF is able to offer paid work at competitive rates to a small number of core contributors. We hope to be able to extend this offer to more core contributors in the future.

Zig Software Foundation Inc

Eliminating obstacles on the path to the comprehensive medical control of aging and age-related disease.

Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.

Longevity Escape Velocity Foundation

The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

Our research-based matching system motivates people to donate to highly effective charities at GivingMultiplier.org.

**[Giving Multiplier](https://givingmultiplier.org)** is a research project created at Harvard University that matches donations to any charity of your choice and promotes the world's most effective charities.

*Resources to get involved:*

- [Make a donation that gets matched](https://givingmultiplier.org)
- [Become a matching funder](http://givingmultiplier.org/matching) (Donations made on this page will also go toward our matching system.)
- [Sign up to our newsletter](http://eepurl.com/i0GHhc)
- [Learn about our philosophy](https://givingmultiplier.org/philosophy)
- [Create your own fundraiser](https://givingmultiplier.org/fundraisers)

Giving Multiplier

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

Aquatic Life Institute is a 501(c)(3) non-profit focused on reducing the suffering of aquatic animals in the global food system.

Aquatic Life Institute (ALI) was founded in 2019 to address the critical and often overlooked issue of aquatic animal welfare. Recognizing that aquatic animals are the most exploited group of animals worldwide yet remain largely unprotected, ALI set out with a mission to drive systemic change and elevate aquatic animal welfare as a priority in global food systems.

Our theory of change is rooted in the belief that by influencing key stakeholders and decision makers, advancing policies, and fostering collaboration, we can drive systemic transformation for billions of aquatic animals. 

Building on this foundation, ALI has emerged as a thought leader, advocating for tangible improvements across the seafood supply chain. By engaging with key stakeholders, including corporations, certification schemes, and policymakers, we work to ensure that aquatic animals trapped in the food system receive the attention they deserve in decision-making processes relating to sustainability and food systems. 

ALI’s work is driven by evidence-based strategies and collaboration. This approach has earned ALI widespread recognition, including a 2024 Top Charity recommendation from Animal Charity Evaluators (ACE). This endorsement solidifies ALI’s position as one of the most effective organizations in the world advancing aquatic animal welfare. 

Aquatic Life Institute Inc

Fostering appreciation and growth of artistic and intellectual creativity in Africa 

Based in Dakar, Senegal, RAW Material Company is a center for art, knowledge and society.  It is an initiative involved with curatorial practice, artistic education, residencies, knowledge production, and archiving of theory and criticism on art. It works to foster appreciation and growth of artistic and intellectual creativity in Africa. The programme is trans-disciplinary and is equally informed by literature, film, architecture, politics, fashion, cuisine and diaspora. RAW Material Company is made of:  - RAW Base, a resource centre specialized in contemporary art;  - RAW Académie, an experimental study programme for artistic thinking and production  - Ker Issa, residencies and studios for artists, curators, authors and researchers.  

RAW Material Company

The Pioneer Academics Opportunity Fund is the non-profit arm that allows us to stay true to our social mission. 

The Pioneer Opportunity Fund is a vital resource that allows us to extend life-changing educational opportunities to high-achieving, low-income students around the globe. Managed by our Fiscal Sponsor, Edward Charles Foundation (ECF), this fund operates under ECF’s 501(c)(3) umbrella, ensuring that your donations are tax-deductible and managed with the highest standards of accountability and integrity.

**Global Non-Profit Partners of Pioneer Academics:**

We are proud partners of leading non-profit organizations supporting high-achieving, low-income students around the world including **Questbridge**, **A Better Chance**, **Jack Kent Cooke Foundation**, **EducationUSA**, **Hali Network**, and **Ukraine Global Scholars**, among many others. 

**Why Your Donation Matters:**

- **Transform Lives**: Your contribution directly supports students who demonstrate exceptional academic potential but lack the financial resources to access co-curricular opportunities.

- **Promote Global Equity**: Pioneer Academics partners with some of the leading domestic and international NGOs that champion equal educational access for the most underserved communities.

- **Empower Future Generations**: Pioneer alumni carry their spirit of trailblazing well beyond their Research Program experience. They become leaders and trailblazers on college campuses and in their careers. 



Pioneer Academics Opportunity Fund

Fondazione Marea unites the Sicilian diaspora to fuel social enterprises and create reasons to stay, return, or move to Sicily.

FONDAZIONE MAREA OVERVIEW

Fondazione Marea aims to be a catalyst for positive transformation for Sicily, harnessing the resources and skills of Sicilians who are scattered around the world. We are a community of Sicilians by birth, adoption and at heart, united by the desire to build a prosperous future for our homeland.

Marea's Vision:  A Sicily with opportunities to stay, return, and arrive. We envision in the long term a dynamic, stimulating, resilient, forward-looking Sicily, attractive to new talent, capable of maximizing its potential, a gateway to the Mediterranean.

Marea's Mission: We aggregate resources and skills of the Sicilian community around the world, to nurture the birth and growth of social enterprises in Sicily.

We enable every person, wherever they are, to actively contribute to the future of Sicily through the generative power of philanthropic investment and social entrepreneurship.

The Foundation is based on three fundamental pillars:

1. Strengthening the link between Sicilians of the diaspora and the changemakers in Sicily
2. Supporting social enterprise ventures 
3. Promoting local development

Our goal is to build an ecosystem of social entrepreneurship, creating job opportunities to break the cycle of depopulation and generate systemic change for the economic, social and cultural development of Sicily.

THE BIRTH OF MAREA 

Marea is a shared dream, a project born out of love for Sicily and the desire to transform this land into a place of opportunity, hope, and growth. It represents an extraordinary community of people with the courage to believe in this dream and the determination to realize it. The idea became a reality in June 2024, starting from zero with a call from Sicily that reached every corner of the world.

The Fondazione Marea-Ente Filantropico ETS was established on December 18, 2024 (video summary) thanks to a six-month Capital Campaign that saw the extraordinary participation of 423 Pioneers (individual donors), the involvement of 3 Sicilian Community Foundations,  €423,000 raised, and the creation of an initial Foundation endowment of €150,000. 

FONDAZIONE MAREA’S IMPACT 

The Foundation aims to turn the tide on Sicily's depopulation phenomenon by significantly reducing the number of people leaving the island in the long term, stopping the talent drain by retaining and attracting young Sicilian graduates and talent, creating more job opportunities in Sicily by reducing NEET status, and developing the philanthropic sector in Southern Italy by closing the gap in the investment by foundations compared to Northern and Central Italy.

UNDERLYING PROBLEMS

Fondazione Marea addresses two main problems:

1. Sicily is endangered. The lack of job opportunities is causing the depopulation of Sicily, forcing young people with high potential to emigrate and condemning many others to NEET status.

According to SVIMEZ - Association for the Development of Industry in Southern Italy data, every year 50,000 people leave Sicily, and the percentage of talented young graduates leaving Sicily in search of opportunities has increased fivefold over time, from 6 percent in 2001 to 32 percent in 2021. In 2080, it is estimated that Sicily will have only 2.8 million residents. Moreover, the Migrantes Foundation 2024 report reveals Sicily to be the Italian region with the highest rate of expatriates, more than 826,000 people. These numbers tell of a veritable diaspora. What is happening profoundly changes the demographic, social, cultural and economic structure of the territory, impoverishing the community and effectively desertifying the Mezzogiorno.

2. The lack of investment by foundations. Foundations play an important role in modern societies: they are private nonprofit institutions that act in the public interest. Because of their history and wealth, they are capable of making a significant impact and can contribute to the growth and development of communities.

Southern Italy has historically suffered from a persistent shortage of foundations, due to the limited circulation of capital and the lack of a philanthropic culture in the area. Meanwhile, Northern and Central Italy benefit in many ways from the presence in their regions of foundations that invest in local businesses and nonprofits, acting as intermediaries between the public and private sectors.

STRATEGY

Fondazione Marea's strategy is based on transforming the diaspora from a threat into an opportunity. It is an innovative model that gathers economic resources and volunteer expertise from the Sicilian community scattered around the world and channels them in a concrete way to support projects with a potential for high social impact. Following the principles of Venture Philanthropy, the Foundation identifies ideas and projects of new social enterprises, Third Sector entities established in corporate form, which play a crucial role in solving social and environmental problems, to respond to the emerging needs of local communities and promote collective welfare. This is currently still a pioneering corporate structure for our local context, with only 63 social enterprises registered in corporate form in the Third Sector across Sicily as of April 11, 2025, compared to 3,334 social cooperatives.

After a regional open call, Marea accompanies each project with incubation and acceleration programs and access to strategic resources. It is Sicilians themselves –  those who have emigrated, returned, stayed, are native or adopted – who supply both a startup fund and the “talent bank,” becoming mentors to the new social entrepreneurs. These new social enterprises generate lasting value in the local area, creating jobs and improving the quality of life. With careful monitoring of results and indicators for measuring social impact, the Foundation collaborates with other Third Sector entities, companies and institutions to complement this commitment by Sicilians and for Sicilians.

THE STARTUP SUPPORT PROGRAM 

Fondazione Marea's startup support program is a structured approach to nurture the birth and growth of social enterprises in Sicily. It is composed of pre-incubation and incubation paths, aimed at both embryonic projects and businesses that have already been established for less than a year. The program offers tailored training, mentoring, access to strategic resources and a dedicated mentor to guide participants through the various stages of development. The goal is to create a social innovation ecosystem, engaging Pioneers (the Foundation's donors), experts, entrepreneurs, networks and investors to generate lasting and systemic impact in Sicily. The program also includes an accelerator track for more mature social enterprises, with the goal of supporting the scalability and replicability of these projects.

The first edition of the startup support program will be launched in May 2025 and will have two simultaneous tracks: one incubation and one acceleration.

The program will be aimed at social enterprises or ETS already established (but not more than 1 year old) or individuals/groups of people who have concrete proposals for social enterprises with implications for the Sicilian context and legal and operational headquarters (including future) in Sicily. Projects can deal with areas that respond to issues and challenges of the Sicilian region such as environment (water risk, drought and fire, agriculture), social (inclusion, immigration), or underutilized tangible and intangible resources.

After a promotional roadshow across Sicily to connect with people potentially interested in participating, at least nine projects (one for each province in Sicily) will be selected to participate. 

The incubation track will last three months in a hybrid mode (online and in-person) with dedicated coaches and access to vertical mentoring sessions. There will be 3 in-person sessions of 3 days each  with theoretical lectures, workshops, hands-on labs, masterclasses, 1-to-1 planning moments, and testimonials.

After the final event to present the social enterprise ideas to the entire Marea Pioneers’ community, projects that meet the requirements for potential growth will be eligible for funding opportunities from the Foundation.

Concurrent with the incubation track will be an acceleration program: A number of social enterprises established for at least 1 year will be selected during an open call based on their track record, impact generated, and potential for scalability and replicability. Over three months, the enterprises will participate in an accelerator with customized training, coaching and mentoring tailored to their needs and those of the market.

Unlike other startup programs, after the formal incubation or acceleration journey, each project will receive long-term assistance through 3 years of mentorship to support the development at the most critical time of a new venture.

Fondazione Marea

ARC is a non-profit research organization whose mission is to align future machine learning systems with human interests. 

See our website for more info about our work. 

Alignment Research Center

Spritely Institute builds, researches, and standardizes networked technology which put people and communities first.


Centralized social media is harmful to society. We are building a gatekeeper-free decentralized system. Our mission is “social media done right”, to put people in control of their own identity and build the technology that would enable a shift to collaborative and intentional security models prioritizing active consent. To accomplish this, we will build a new architecture for the internet: removing the necessity of client-server architecture, replacing it with a participatory peer-centric model.

Spritely’s technology is being released as free and open source software aiming for multiple programming language implementations and eventual open standardization. All of our work, ranging from decentralized identity, peer-to-peer user agents, decentralized social networks, encrypted and portable storage, and distributed object programming infrastructure is being built to enable a gatekeeper-free path where users and content are not tied to a specific server.

Spritely Networked Communities Institute

Protecting free expression and enabling secure global communication through open source privacy technology.

Long before we knew that it would be called Signal, we knew what we wanted it to be. Instead of teaching the rest of the world cryptography, we wanted to see if we could develop cryptography that worked for the rest of the world. At the time, the industry consensus was largely that encryption and cryptography would remain unusable, but we started Signal with the idea that private communication could be simple.

Since then, we’ve made some progress. We’ve built a service used by millions, and software used by billions. The stories that make it back to us and keep us going are the stories of people discovering each other in moments where they found they could speak freely over Signal, of people falling in love over Signal, of people organizing ambitious plans over Signal. When we ask friends who at their workplace is on Signal and they respond “every C-level executive, and the kitchen staff.” When we receive a subpoena for user data and have nothing to send back but a blank sheet of paper. When we catch that glimpse of “Signal blue” on a metro commuter’s phone and smile.

However, we’ve always wanted to do much more, and our limitations have often been challenging. Over the lifetime of the project, there have only been an average of 2.3 full-time software developers, and the entire Signal team has never been more than 7 people. With three client platforms to develop, a service to build and run, a growing list of integrations to assist with, and millions of users to support, that has often left us wanting.

Even so, Signal has never taken VC funding or sought investment, because we felt that putting profit first would be incompatible with building a sustainable project that put users first. As a consequence, Signal has sometimes suffered from our lack of resources or capacity in the short term, but we’ve always felt those values would lead to the best possible experience in the long term. The Signal Foundation completes our vision of Signal operating as part of a full 501(c)(3).

Signal Technology Foundation

Terra Praxis designs and implements strategies that leverage science, technology and energy innovation for a prosperous planet

We co-founded TerraPraxis to design and implement strategies that leverage science, technology and energy innovation for a prosperous planet. Our mission is to innovate and accelerate scalable, equitable solutions for unsolved areas of the climate challenge. 

Our special focus is on enabling high-impact rapid transitions for neglected parts of the decarbonization challenge. 

We work with an extensive global network to define, incubate and initiate scalable strategies that fulfil the twin missions of prosperity and decarbonization. 

Terra Praxis

Committed to stamping out muscular dystrophy

Strongest Hearts is so excited to have you here.  We founded Strongest Hearts in 2022 after our son’s diagnosis with Becker’s Muscular Dystrophy.  BMD is an incredibly serious disease that affects the muscle systems of young boys and men.  Like the more common and more severe Duchenne’s, it is progressive and life threatening.

Strongest Hearts intends to end that threat.  Our non-profit is designed to exclusively work to find a cure or treatment, educate and advocate for this deadly disease.  DMD is the number one killer for adolescents in the US and we search to find a solution that will help over 90% of the DMD and BMD community.  

Like so many people and families, we have felt fear, anxiety and hopelessness and have received massively conflicting data from doctors and websites.  It is time to stop that cycle and move towards a day when we can say that a diagnosis of any muscular dystrophy, while unsettling, is no longer a tragedy.  We truly believe that we have the people, the skill and the technology to end this scourge once and for all.  

Join us in our fight.  Many Hearts, One Mission

Strongest Hearts Foundationis a project of Players Philanthropy Fund a Maryland charitable trust recognized by IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178). Contributions to Strongest Hearts Foundationqualify as tax-deductible to the fullest extent of the law. 




Strongest Hearts Foundation

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.

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We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

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GiveDirectly

Zig Software Foundation Inc

Alliance for Longevity Science, Arts & Entertainment

Longevity Escape Velocity Foundation

GiveDirectly

Top Charities Fund

Research