We need this knowledge preserved and passed down to new generations. These medicines should be used with reverence and as tools for healing and spiritual communion. Maria Sabina and the Mazatecas have this knowledge—we should learn from them.

I'm very excited about work to improve forecasting and interactively explain AI progress. Sage's projects are some of the best and most useful I've come across in both domains.

I'm excited at the advancements in AI and I appreciate METR and their work.

I believe in supporting AI research and benchmarks such as this!

Excited to support ARC and the next wave of AGI benchmarks!

The Fungi Foundation is a global organization that works for the Fungi, their habitats, and the people who depend on them.

Launched in 2012, the Fungi Foundation is the first NGO dedicated to the fungi kingdom. Since its inception, it has achieved numerous milestones while dedicating itself to exploring the fungi world in view of increasing knowledge of their diversity, educating about their applications, and recommending public policy for their conservation. As part of our ongoing 3F initiative, the foundation played a key role in enabling Chile to become the first country in the world to include protection of fungi in its environmental legislation. More recently, the foundation proudly announced the Fantastic Fungi Education Curriculum, the world's first mycological set of courses designed for schools.

In short, the Fungi Foundation envisions a healthy planet in which Fungi are recognized, protected, and embraced as the interconnectors of nature; a mission that would be impossible without the essential support of our kind, engaged donors.

Fungi Foundation

Sage builds tools to make sense of the future. Our projects include Fatebook and AI Digest.

Sage builds tools to make sense of the future. Our projects include:

- [AI Digest](https://theaidigest.org/): Visual explainers on AI capabilities and their effects
- [Fatebook](https://fatebook.io/): The fastest way to track your predictions
- [Quantified Intuitions](https://www.quantifiedintuitions.org/): Practice assigning credences to outcomes with a quick feedback loop

Sage Future

A research nonprofit that works on assessing whether cutting-edge AI systems could pose catastrophic risks to society.

METR (Model Evaluation and Threat Research) builds the science of accurately assessing risks, so that humanity is informed before developing transformative AI systems.

We believe that AI could change the world quickly and drastically, with potential for both enormous good and enormous harm. We also believe it’s hard to predict exactly when and how this might happen.

At some point, AIs will probably be able to do most of what humans can do, including developing new technologies; starting businesses and making money; finding new cybersecurity exploits and fixes; and more.

We think it’s very plausible that AI systems could end up pursuing goals that are at odds with a thriving civilization. This could be due to someone’s deliberate effort to cause chaos, or happen despite the intention to only develop AI systems that are safe.

Given how quickly things could play out, we don’t think it’s good enough to “wait and see” whether there are dangers.

We believe in vigilantly, continually assessing risks. If an AI brings significant risk of a global catastrophe, the decision to develop and/or release it can’t lie only with the company that creates it.

METR

ARC Prize Foundation builds and deployed AI benchmarks that measure and guide research

ARC Prize launched in 2024 as an experiment to promote the relatively obscure, but important, ARC-AGI benchmark. Now, after our OpenAI o3 testing, nearly everyone in tech has heard of it. But there is much more work to do to reach AGI. There remains many things that are easy for humans, but hard for AI.

ARC Prize Foundation

Spritely Institute builds, researches, and standardizes networked technology which put people and communities first.


Centralized social media is harmful to society. We are building a gatekeeper-free decentralized system. Our mission is “social media done right”, to put people in control of their own identity and build the technology that would enable a shift to collaborative and intentional security models prioritizing active consent. To accomplish this, we will build a new architecture for the internet: removing the necessity of client-server architecture, replacing it with a participatory peer-centric model.

Spritely’s technology is being released as free and open source software aiming for multiple programming language implementations and eventual open standardization. All of our work, ranging from decentralized identity, peer-to-peer user agents, decentralized social networks, encrypted and portable storage, and distributed object programming infrastructure is being built to enable a gatekeeper-free path where users and content are not tied to a specific server.

Spritely Networked Communities Institute

ISSH: Quality Education, Free and Fearless, For the Deprived

The Institute for Social Sciences and Humanities (ISSH) provides tuition-free, high-quality education in the social sciences and humanities to deprived and underserved communities. Qualified at Level 7 of the European Qualifications Framework, ISSH offers a one-year Master's-level study program, hosts an open online courses platform with over 15,000 users, and fosters innovative knowledge exchange through its research and innovation center.

ISSH University Press publishes scholarly books and journals, organizes biannual, bilingual international conferences, and empowers civil society through accessible education. ISSH creates lasting, meaningful change for deprived and underserved communities by promoting academic freedom and expanding access to learning opportunities.

Your donations and support are vital to sustaining ISSH's unique mission. Join us today by participating in one of these two campaigns:

- **Support our “**[End-of-Year Giving Campaign](https://www.every.org/issh/f/end-the-year-with-purpose)**.”**
- **Make a “**[Lasting Gift to Future Generations](https://www.every.org/issh/f/your-lasting-gift-to)**” by helping grow our endowment for long-term sustainability.**

Together, we can create opportunities through the power of education.

Institute For Social Sciences And Humanities

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

Zig is a general-purpose programming language and toolchain for maintaining robust, optimal, and reusable software.

The Zig Software Foundation is a non-profit corporation founded in 2020 by Andrew Kelley, the creator of Zig, with the goal of supporting the development of the language. Currently, the ZSF is able to offer paid work at competitive rates to a small number of core contributors. We hope to be able to extend this offer to more core contributors in the future.

Zig Software Foundation Inc

We match donations to any charity you choose while introducing you to super-effective charities. Learn more: GivingMultiplier.org

[**Giving Multiplier**](https://givingmultiplier.org) is a research project created at Harvard University that adds matching funds to any charity of your choice while introducing donors to highly effective charities recommended by experts.

*Resources:*

- [Make a donation that gets matched](https://givingmultiplier.org)
- [Become a matching funder](http://givingmultiplier.org/matching) (Donations made on this page will also go toward our matching system.)
- [Sign up to our newsletter](http://eepurl.com/i0GHhc)
- [Learn about our philosophy](https://givingmultiplier.org/philosophy)

Questions? Email us: **info@givingmultiplier.org**

Giving Multiplier

Aquatic Life Institute is a 501(c)(3) non-profit focused on reducing the suffering of aquatic animals in the global food system.

Aquatic Life Institute (ALI) was founded in 2019 to address the critical and often overlooked issue of aquatic animal welfare. Recognizing that aquatic animals are the most exploited group of animals worldwide yet remain largely unprotected, ALI set out with a mission to drive systemic change and elevate aquatic animal welfare as a priority in global food systems.

Our theory of change is rooted in the belief that by influencing key stakeholders and decision makers, advancing policies, and fostering collaboration, we can drive systemic transformation for billions of aquatic animals. 

Building on this foundation, ALI has emerged as a thought leader, advocating for tangible improvements across the seafood supply chain. By engaging with key stakeholders, including corporations, certification schemes, and policymakers, we work to ensure that aquatic animals trapped in the food system receive the attention they deserve in decision-making processes relating to sustainability and food systems. 

ALI’s work is driven by evidence-based strategies and collaboration. This approach has earned ALI widespread recognition, including a 2024 Top Charity recommendation from Animal Charity Evaluators (ACE). This endorsement solidifies ALI’s position as one of the most effective organizations in the world advancing aquatic animal welfare. 

Aquatic Life Institute Inc

Developing the roadmap for a sustainable, secure, and just global protein supply 🧫🌱


Check out what your support makes possible at gfi.org/your-impact. 

The Good Food Institute (GFI) is a global network of nonprofit organizations developing the roadmap for a sustainable, secure, and just protein supply. Industry alone will not meet this challenge at the scale or speed we need. GFI is accelerating the transformation of the food system by identifying solutions and mobilizing resources to make alternative proteins the default way meat is made.

GFI is a network of nonprofits around the world strategically based in the most critical economies for alternative protein advancement. In Asia, Europe, Brazil, India, Israel, and the U.S., GFI’s teams are mobilizing the international community to use markets and technology to replace harmful practices with ones that are better for the climate and biodiversity, for food security, and for global health.

GFI’s Focus
As a nonprofit, GFI is uniquely positioned to accelerate the transition to alternative proteins by focusing on three programmatic priorities:

-Cultivating a strong scientific ecosystem | GFI’s science and technology teams map out the most neglected areas that will allow alternative proteins to compete on taste and price. GFI meets these challenges by developing open-access research and resources, educating and connecting the next generation of scientists and entrepreneurs, and funding research that benefits alternative protein development across the sector. 

-Influencing policy and securing government funding | GFI’s policy teams ensure that alternative proteins are a part of the policy discussion around climate change mitigation and global health. In every region where GFI has a presence, teams advocate for government funding and incentives to transition to alternative proteins and are paving the way for the approval of novel proteins such as cultivated meat.

-Ensuring industry prioritizes alternative proteins | GFI’s corporate teams are creating a transformation of our global meat supply. GFI works to replicate past market transformations by showing companies of all sizes, from startups to multinational corporations, how alternatives to animal products can be profitable while meeting environmental, social, and governance goals.

Reimagining meat
The very real threats of climate change, global food insecurity, antibiotic resistance, and pandemics require us to imagine a different future of food. Alternative proteins are the solution that will securely and sustainably feed the world.

GFI’s global community of scientists, policy experts, and corporate specialists are creating a world where alternative proteins are no longer alternative.



The Good Food Institute

We are New Harvest, the cellular agriculture nonprofit. We’re growing meat, milk & eggs from cells instead of animals.

New Harvest was founded in 2004 to support the development of cultured meat (AKA “lab-grown meat”) and other cell culture-based foods. 

Our mission is to ensure cellular agriculture delivers on its promises to create a more equitable & sustainable food system by ending our dependence on animal agriculture. 

We fund public research and industry-wide initiatives to accelerate scientific breakthroughs and steward this tech toward making the world a better place. 

New Harvest

Hong Kong Watch defends human rights, freedoms and the rule of law in Hong Kong.

Hong Kong Watch is a [UK registered charity](https://register-of-charities.charitycommission.gov.uk/charity-details/?regid=1180013&subid=0) founded in 2017, consisting of Hong Kongers and friends of Hong Kong, working closely with Hong Kong community groups in the diaspora.

We inform and educate legislators, policy-makers and the media, and raise awareness among the wider public, about the violations of human rights, basic freedoms and the rule of law in Hong Kong, and advocate for actions to assist Hong Kongers. We do this through a combination of in-depth research reports, regular topical briefings, opinion editorials, media briefings and interviews, and advocacy campaigns.

We also help integrate, support, welcome and strengthen the capacity of the Hong Kong diaspora, through a programme of civic and political education and community engagement.



*Information about donation security and donor benefits is available [here](https://www.hongkongwatch.org/donate).*

Hong Kong Watch

The IWM is a non-profit institution that promotes intellectual work and enables encounters of people around ideas. 

The Institute for Human Sciences (IWM Vienna) is an institute of advanced studies in the humanities and social sciences founded in 1982. We promote intellectual exchange across disciplines, between academia and society, and among regions that now embrace Eastern, Central and Western Europe, the Global South and North. We aim to reframe larger questions of academic debate and public interest that address today's complex challenges. We believe that sustained intellectual work and its broad dissemination is essential to a humane future of open, just, and sustainable societies. 

Institut für die Wissenschaften vom Menschen (IWM)

Zera Bolivia Foundation fosters indigenous-led education, enabling self-empowerment, financial independence, and social mobility.

**Zera Bolivia** is an Aymara-led foundation that hosts classes and events for kids as a response to colonial norms, championing indigenous self-determination—especially for women and girls—through transformative education grounded in emotional intelligence, critical thinking, self-awareness, and practical tools for financial independence.

We began in 2015 with a socio-emotional learning pilot at a women’s prison in La Paz, and have since grown to reach thousands of children, youth, and families across Bolivia’s nine departments. Collaborating with municipal governments, the Ministry of Education, and local communities, we co-create culturally adapted programs that honor each community’s priorities and values. Thanks to our community and donor support, we have provided training, world-class educational materials, and technology infrastructure to prisons, children’s hospitals, rural areas, schools, and grassroots groups—always centering local leadership.

From the “Qantatai” literature podcast to “Bolivian Thinkers for Everyone By Zera,” our initiatives celebrate Bolivia’s intellectual heritage and open new pathways for dialogue and growth. Participants often report stronger emotional well-being, improved academic performance, and greater economic opportunities. As we look to the future, we are developing our first “STEM for Indigenous Young Women” program in El Alto and across 20 rural provinces of La Paz, in partnership with India’s STEMED NETWORK.

When you support Zera Bolivia, you invest in locally driven, inclusive solutions that affirm the power of Indian communities to shape their own destiny. Your contribution furthers our shared vision of a Bolivia where education is a tool for self-empowerment, cultural pride, and lasting social change.

Zera Bolivia Foundation

Karl Coke Evangelistic Association Incorporated is a nonprofit organization focusing on Timothy Seminaries International.

At Timothy Seminaries International, we combine rigorous academic training with a deep spiritual foundation to equip individuals with the knowledge and tools needed to explore the Bible from its roots. Accredited by the Transworld Accrediting Commission International, we are committed to inspiring and empowering Christian families, leaders, and individuals to become effective stewards of God’s Word.

Timothy Seminaries International

Odylia Therapeutics is a nonprofit biotech working to accelerate the development of treatments for people with rare diseases.

At Odylia, we accelerate therapeutic development for people with rare diseases, changing the way treatments are brought from the lab to the clinic. We strive to bring life altering treatments to people with genetic disease regardless of prevalence or commercial interest. 
Odylia is shifting the paradigm to focus on proven science and removing traditional roadblocks. We work to lower costs, reduce development time, focus research, and continuously drive successful programs towards clinical trials and regulatory approval. Strategic collaborations with patient groups, research labs, and commercial partners facilitate our work to ensure treatments are safe, effective, and ultimately reach patients who need them.

Odylia challenges the traditional approach to drug development through:

1. Lower cost of development
Lower licensing fees to decrease development costs and ensure continued commitment to program success
2. Increase speed of development
Challenge traditional approaches through regulatory engagement

Streamline development through strategic partnerships and a platform approach to drug development

3. Enable the entire ecosystem
Provide expertise through in-house Brydge Solutions and leveraging the Odylia Board

Enable the entire ecosystem through Initiatives that impact the broader field

Odylia Therapeutics

Extending and improving the lives of people with ALK+ lung cancer by raising funds for research and patient support programs.

**Our Vision**

We envision a world where ALK+ lung cancer is a chronic or even curable condition and the next person diagnosed with lung cancer does not have to live under the current stigma.

**Our Start**

\#SweatForBreath started as a grassroots fundraising campaign during Lung Cancer Awareness Month in 2023. After being diagnosed with Stage IV ALK+ lung cancer in November 2022, David Cornbrooks became keenly aware that he was benefiting from the selfless fundraising and awareness efforts of the patients before him.

[Listen to David's story here.](https://www.youtube.com/watch?v=lWcS-yN7Qxw)

The \#SweatForBreath campaign in 2023 became David, and his wife, Lisa’s, way to help the next generation ALK+ lung cancer patients.

\#SweatForBreath accelerated beyond more than just a typical fundraiser.  The initiative quickly evolved into a community of patients, caregivers, family, and friends seeking to make David and Lisa's vision a reality and the road to that vision more tolerable. People donated, sweat at the in-person cycle event, posted on social media, and helped fundraise through organizing group walks, selling art, "gifting" donations on behalf of clients, and much more.

Their success in 2023 compelled David and Lisa to officially transition the \#SweatForBreath campaign into the Sweat For Breath Foundation, operating through a fiscal sponsorship with Players Philanthropy Fund, a Maryland charitable trust recognized by IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178).

**Our Impact**

Since 2023, over **1,450 donors** have given nearly **$400,000** to the Foundation (or its predecessor campaign). 100% of the proceeds have gone directly to The Johns Hopkins Sidney Kimmel Center in Baltimore, MD to support Dr. Vincent Lam’s ALK+ lung cancer research.

This support provided the critical funding needed to launch Dr. Lam’s clinic trial, which will evaluate the safety of a cancer peptide vaccine to prevent or delay acquired resistance in advanced ALK+ lung cancer patients currently on ALK targeted therapy. Dr. Lam’s vaccine is the **first ALK+ vaccine in the world** to be tested in a clinical trial. Dr. Lam administered the vaccine to the first patient **in clinic on May 13, 2024**!

-----------

*The Sweat for Breath Foundation is a project of Players Philanthropy Fund, Inc. a Texas nonprofit corporation recognized by IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178,[ppf.org/pp](https://ppf.org/pp)). Contributions to The Sweat for Breath Foundation qualify as tax-deductible to the fullest extent of the law.*


The Sweat For Breath Foundation

We aim to advance the mental wellbeing of our South Asian community.

In 2021, during their freshman year of college, our founders Ravi Parekh and Aaron Pandian suffered the loss of their close friend and roommate, Farhan, in a tragic murder-suicide where he took the lives of himself and his family. 

Farhan was struggling with a variety of inadequately treated mental illnesses. However, like so many members of the South Asian-American community, his parents simply lacked the tools, resources, and education necessary for providing him the care he needed.

They recognized that, as an immigrant South Asian family, they lacked the tools, resources, and education necessary for providing Farhan the care he needed. The tragedy of Farhan and his family revealed that there are many mental health issues unique to the cultural characteristics of South Asians. Understanding that these environmental factors and structural barriers to effective care created the situation which led to this tragedy, we theorized a youth-led grass-roots advocacy and education initiative that equips South Asian youth and other interested parties with access to tools and resources to understand, process, and empower.

Grass-roots efforts are often inspired by lived experiences. Our passion and drive to bridge the gaps in mental health care for South Asian individuals stem from our lived experiences.

Knowledge is empowering, and part of understanding mental health is to both learn and express empathy for those affected who are unable to receive effective care. To learn not to fear mental illness as a sibling, parent, friend, significant other, or affected individual and employ newly acquired tools that work to connect with the resources they need. 

MHISA embodies these ideals and provides us an outlet to engage those around us with a shared goal: to enable South Asians struggling with mental illness to lead better and healthful lives.

Mental Health Initiative for South Asians

Eliminating obstacles on the path to the comprehensive medical control of aging and age-related disease.

Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.

Longevity Escape Velocity Foundation

The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

Trains and empowers educators/leaders to create racially equitable, safe, and empowering educational spaces for all youth.

The Center for Racial Justice in Education (CRJE) works to construct a new reality within our country's public school system; a world where all young people learn and thrive in equitable and affirming educational spaces. CRJE’s work with districts, schools, organizations, and community members result in empowered educators and leaders who are better equipped to build educational institutions that foster equitable outcomes, and ensure that all students have safe, inclusive, and culturally responsive spaces to learn.

 Since 2012 alone CRJE has trained over 17,000 educators/leaders, reached over 167,000 youth, and worked with over 400 educational partners in 17 states. Our work consists of intensive leadership and professional development trainings, longer-term, in-depth coaching and consultation, community-driven climate assessments, and youth-adult partnerships, all customized to meet the unique needs of each educational partner. In the long-term, through collective practice for educational equity at the institutional level, and through mutually accountable partnerships and coalition building at the community level, we aim to build an education system and spaces where all youth feel safe, and have access to a high-quality education. In this system, we will see:

- Students who are emotionally, physically and academically thriving. 
- Educators and leaders who have an ongoing, consistent practice of building educational communities grounded in equity. 
- Caregivers who are empowered to actively engage in community building.
- Public policy that has shifted to reflect racial equity and justice in education.

Center for Racial Justice in Education (CRJE)

Strengthening democracy for all voters by promoting the responsible use of technology in elections.

Verified Voting’s mission is to strengthen democracy for all voters by promoting the responsible use of technology in elections. We are a non-partisan organization focused exclusively on the critical role technology plays in election administration. Our staff, Board, and Board of Advisors consist of nationally-recognized subject matter experts on the issue of election integrity and the responsible use of technology. Since our founding in 2004 by computer scientists, we have acted on the belief that the integrity and strength of our democracy rely on citizens’ trust that each vote is counted as cast. In the ever-shifting world of election security, where new threats or challenges can emerge at any time, we are working to guide elections toward greater accuracy, security, and verifiability.

Verified Voting

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.

GiveWell

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We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

Choose a donation for Every.org

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Ex-cofounder and Head of Engineering at Every.org. I work so others can receive the level of support I've personally benefited from.

founder @ camp.org, expa.com, uber.com & mix.com

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Fungi Foundation

ARC Prize Foundation

Sage Future

ARC Prize Foundation

METR

Spritely Networked Communities Institute

Research