Zig is a very sharp tool, that is exactly what I need.

I like the way you communicate and that you have a definite vision that mostly aligns with my needs. With my background in decades-of-C, zig feels very satisfactory. Thank you.

ConnectMyVariants work in the community saves lives! 

Zig is a general-purpose programming language and toolchain for maintaining robust, optimal, and reusable software.

The Zig Software Foundation is a non-profit corporation founded in 2020 by Andrew Kelley, the creator of Zig, with the goal of supporting the development of the language. Currently, the ZSF is able to offer paid work at competitive rates to a small number of core contributors. We hope to be able to extend this offer to more core contributors in the future.

Zig Software Foundation Inc

ConnectMyVariant's mission is to end hereditary disease by bringing families together.

ConnectMyVariant is an educational health-focused 501(c)3 nonprofit organization that supports individuals and families with hereditary disease in their early detection and prevention efforts. We provide unique value by leveraging our evidenced-based family connection protocols to help people identify other at-risk relatives and help those relatives access genetic testing so that they can get optimal medical care. ConnectMyVariant brings people with the same genetic risk together through our variant database and community engagement events to share experiences and find common ancestors. ConnectMyVariant also works to increase awareness of the benefits of family outreach among physicians, others who provide prevention care, and the broader genealogy community.
 
Our key activities are:

- Working with patients to implement personalized family outreach plans
- Interactive educational workshops about sharing information on inherited disease risk
- Variant specific family reunions to share stories and plan outreach to cousins
- Genealogy assistance to help connect individuals in variant groups
- Individual equity and inclusion grants for family and community outreach

Need and Impact:
When hereditary disease risk is known, family outreach has been proven to be the most effective and cost-effective intervention for early detection and prevention. This family outreach, also known as cascade testing, is recommended by multiple guidelines. Despite overwhelming evidence, family outreach assistance is not reimbursed by insurance or integrated into healthcare. Many people suffer and die from hereditary disease that could have been prevented or caught early.
 
We have shown that our strategies to encourage family outreach can act as a communication multiplier. Our pilot research at the University of Washington showed that this approach enhanced patient experience, was considered ethical, and was appreciated by newly identified relatives. Our approach is low-cost and is 25 to 50 times more effective than awareness and education interventions that target the general population.

Equity and Inclusion:
ConnectMyVariant is committed to being a leader for equity, diversity, and inclusion in hereditary disease prevention. ConnectMyVariant’s goal is to spread awareness among all individuals and families about inherited disease risk. All project staff, participants, and partners in ConnectMyVariant have an equal voice in developing innovative ways to improve hereditary disease outreach and prevention for all people. By fostering a diverse and inclusive community, we can provide knowledge and opportunities that have been historically inaccessible to millions of people.

ConnectMyVariant

Our research-based matching system motivates people to donate to highly effective charities at GivingMultiplier.org.

**[Giving Multiplier](https://givingmultiplier.org)** is a research project created at Harvard University that matches donations to any charity of your choice and promotes the world's most effective charities.

*Resources to get involved:*

- [Make a donation that gets matched](https://givingmultiplier.org)
- [Become a matching funder](http://givingmultiplier.org/matching) (Donations made on this page will also go toward our matching system.)
- [Sign up to our newsletter](http://eepurl.com/i0GHhc)
- [Learn about our philosophy](https://givingmultiplier.org/philosophy)
- [Create your own fundraiser](https://givingmultiplier.org/fundraisers)

Giving Multiplier

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

Extending and improving the lives of people with ALK+ lung cancer by raising funds for research and patient support programs.

**Our Vision**

We envision a world where ALK+ lung cancer is a chronic or even curable condition and the next person diagnosed with lung cancer does not have to live under the current stigma.

**Our Start**

\#SweatForBreath started as a grassroots fundraising campaign during Lung Cancer Awareness Month in 2023. After being diagnosed with Stage IV ALK+ lung cancer in November 2022, David Cornbrooks became keenly aware that he was benefiting from the selfless fundraising and awareness efforts of the patients before him.

[Listen to David's story here.](https://www.youtube.com/watch?v=lWcS-yN7Qxw)

The \#SweatForBreath campaign in 2023 became David, and his wife, Lisa’s, way to help the next generation ALK+ lung cancer patients.

\#SweatForBreath accelerated beyond more than just a typical fundraiser.  The initiative quickly evolved into a community of patients, caregivers, family, and friends seeking to make David and Lisa's vision a reality and the road to that vision more tolerable. People donated, sweat at the in-person cycle event, posted on social media, and helped fundraise through organizing group walks, selling art, "gifting" donations on behalf of clients, and much more.

Their success in 2023 compelled David and Lisa to officially transition the \#SweatForBreath campaign into the Sweat For Breath Foundation, operating through a fiscal sponsorship with Players Philanthropy Fund, a Maryland charitable trust recognized by IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178).

**Our Impact**

Since 2023, over **1,450 donors** have given nearly **$400,000** to the Foundation (or its predecessor campaign). 100% of the proceeds have gone directly to The Johns Hopkins Sidney Kimmel Center in Baltimore, MD to support Dr. Vincent Lam’s ALK+ lung cancer research.

This support provided the critical funding needed to launch Dr. Lam’s clinic trial, which will evaluate the safety of a cancer peptide vaccine to prevent or delay acquired resistance in advanced ALK+ lung cancer patients currently on ALK targeted therapy. Dr. Lam’s vaccine is the **first ALK+ vaccine in the world** to be tested in a clinical trial. Dr. Lam administered the vaccine to the first patient **in clinic on May 13, 2024**!

-----------

*The Sweat for Breath Foundation is a project of Players Philanthropy Fund, Inc. a Texas nonprofit corporation recognized by IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178,[ppf.org/pp](https://ppf.org/pp)). Contributions to The Sweat for Breath Foundation qualify as tax-deductible to the fullest extent of the law.*


The Sweat For Breath Foundation

Eliminating obstacles on the path to the comprehensive medical control of aging and age-related disease.

Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.

Longevity Escape Velocity Foundation

Wonder Cabinet is a space for artistic production, social and cultural development in Bethlehem, Palestine.

**The Wonder Cabinet is a space for artistic production, education, social and cultural development inaugurated in Bethlehem, Palestine in May 2023.** 

As a non-for profit company for arts and culture, Wonder Cabinet fosters encounters among individuals and entities from different backgrounds and geographies to conceive and implement original research, educational, and community-building projects encompassing the visual and sound arts, artisanship, design and architecture, food, land-care and heritage, with an approach built on knowledge exchange and cooperative labor. 

Supported by a lively community and operating in collaboration with local and international partners, Wonder Cabinet centers creativity and collectivity to generate unexpected encounters in, with and around the space, with an original program of residencies, exhibitions, research projects, workshops, screenings, performances, listening sessions, lectures, culinary programs, land-care and community-based initiatives. 

The space - a new building designed by founders and architects Elias and Yousef Anastas (AAU Anastas, Local Industries) - comprises a production facility, artist studios, a multipurpose hall, a listening bar and food laboratory, a store, a sound production and Radio Alhara station, and a community garden. 

The Wonder Cabinet is committed to growing a network of collaborative relationships with individuals, private and public entities - local and international - to contribute to the design, sustainability, and implementation of its projects and programs.

Individuals, companies, independent initiatives, and institutions who believe in creativity, research, collective learning and knowledge exchange as tools for resilience and cultural development, have the opportunity to take part in Wonder Cabinet’s life by contributing through financial, in-kind, programmatic and/or technical support.

In relation to the extent of the collaboration, the best return of visibility and dedicated services and opportunities will be designed together with the partners. 

By supporting Wonder Cabinet, you will contribute to the development of the artistic and cultural sector in Palestine; to the empowerment of young artists, practitioners and creatives; and to the engagement and wellbeing of the local community.

The Wonder Cabinet

SEF designs and implements state-wide training programs for teachers & principals, to make learning more engaging & impactful.

**About Us**

Founded in 2013, **Simple Education Foundation (SEF)** is dedicated to transforming education in India’s government schools by empowering teachers to create meaningful and impactful learning experiences. Our work began with **Prayog Shala**, a community learning center in Delhi, and has since expanded across multiple states, impacting over 160,000 teachers and students.

At SEF, we collaborate with state governments to design and implement **statewide teacher training programs**, focusing on sustainable, region-specific solutions. We co-design frameworks with educators to ensure that these programs are scalable and self-sustaining. Through our programs, we aim to bridge the gap in education quality between government and private schools, equipping teachers with the skills and support needed to provide excellent education to all children.

With our latest initiative, **Teachers for Tomorrow**, we’re preparing the next generation of educators to lead classrooms that inspire learning, growth, and social change. Our mission is to reach **1 million teachers by 2028**, ensuring that every child in India has access to high-quality education.

**Our Mission**

At SEF, our mission is to empower **1 million teachers by 2028**, transforming classrooms across India and ensuring every student receives a high-quality education. We aim to equip teachers to become catalysts for change, creating equitable learning environments where every child can thrive, regardless of their socio-economic background.

**Our Vision**

Our vision is clear: every child in India should have access to high-quality education that paves the way for a brighter future. We are committed to breaking down barriers to education, ensuring that no child’s potential is limited by their circumstances.

**Our Programs and Journey**

In 2016, SEF took a significant step by partnering with the state government of Jammu & Kashmir to launch a teacher training program for over 85,000 teachers. This success marked a turning point, allowing us to dive deeper into our mission of teacher development and educational transformation.

That same year, we started working in Uttarakhand, where we established a community learning center in the village of Gular. This program has since evolved into several initiatives, including the Sashak Prathamik program, which today works with five primary schools in the Tehri Garhwal region. We also collaborate with the Narendra Nagar block to develop and facilitate their mentor teacher coaching and training programs.

In 2017, we launched our Centers of Excellence program in Delhi, working with seven government primary schools. Today, we continue to partner with three of these schools, focusing on enhancing learning outcomes and teacher effectiveness.

By 2021, SEF had extended its partnership with the Delhi government and SCERT to design and implement a competency-based teacher training program aimed at strengthening teacher competencies and the mentor teacher program across the state.

This year, we expanded our work to include collaborations with the state governments of Uttarakhand and Punjab. Our efforts focus on delivering comprehensive teacher development programs that include both training and coaching, developed in close partnership with block and district resource officials.

Our newest initiative, Teachers for Tomorrow (formerly Future Teacher Program), launched in 2022, is designed to equip aspiring teachers with the skills and mindset necessary to become exceptional educators. Under this program, we aim to ensure that these future educators are fully prepared to lead classrooms that inspire and nurture the next generation.

**Our Achievements**

•	Impacted more than 160,000 teachers across Delhi, Uttarakhand, Punjab, and Jammu & Kashmir.

•	Established eight government partnership schools, setting new standards for quality education.

•	Team members and individuals associated with SEF have been selected as fellows with prestigious global organizations such as Acumen, the Dalai Lama Program, WISE Qatar, Teach for All, and more.

•	SEF has participated in and presented at national and international conferences, contributing to thought leadership in the field of education through research papers and findings.

•	Recognized as a “Great Place to Work” for three consecutive years.

**Future Plans**

Looking ahead, SEF is focused on scaling our impact across multiple states and programs. Currently, under the Centers of Excellence program within our Government Partner School Program, we work with eight schools in Uttarakhand and Delhi. Our State In-Service Teacher Training Programs span Delhi, Punjab, and Uttarakhand, and in 2024, we aim to cumulatively impact over 1.5 lakh teachers through workshops, coaching programs, training sessions, and the provision of tools and resources.

Through our Teachers for Tomorrow program, which focuses on pre-service teacher education, we will work with over 2,000 aspiring teachers across several institutes in Delhi. This year, we also plan to pilot innovative programs that will help define and refine our strategy for developing the teachers of the future.

Our journey has been bolstered by the support of several esteemed organizations, including the Wipro Foundation, InfoEdge, Max India Foundation, Anu Agha and Meher Padamji Family Office, the Bikchandani Family Office, Padmini, V&A, Forest Essentials, Boston Consulting Group, and others. We have also built strong partnerships with government agencies across Jammu & Kashmir, Delhi, Uttarakhand, and Punjab.

As we move forward, SEF remains committed to building sustainable, scalable solutions for India’s education system, driven by the belief that every child deserves access to high-quality education.

**Looking Forward**

As we look ahead to 2028, SEF’s goal is to continue expanding our impact, reaching 1 million teachers and transforming classrooms across India. By strengthening teachers, we strengthen the future of our children and our nation.

**For more information, visit our website at www.simpleeducationfoundation.org.**

Simple Education Foundation

Delivering unconditional cash directly to the world's poorest households via secure mobile transfers. 

Since 2009, GiveDirectly has delivered more than $580 million in unconditional cash transfers to families in need. These one-time cash transfers allow recipients to invest in what they need most and have been shown to improve their earnings, children’s school attendance, health, nutrition, and mental well-being.
 
GiveDirectly uses government data to target villages where most or all residents are living in extreme poverty, defined by the World Bank as earning under $2.15/day. In-country GiveDirectly staff enroll one member of each household in the entire village to receive a one-time transfer of about $1,000 USD sent in two installments using mobile money. Recipients can then withdraw the mobile funds as cash with local agents and use the funds to invest in what they need – whether it’s on starting a business, education, making their home safer/sturdier, healthcare, or livestock.
 
GiveDirectly uses rigorous experimental research (randomized controlled trials) to measure the impact of their unconditional cash programs and answer public policy questions, generating evidence on key design and implementation questions across varied contexts. You can find over 300 studies on the positive impacts of cash transfers in GiveDirectly’s Cash Research Explorer.

GiveDirectly

We are a think tank dedicated to figuring out the best ways to make the world a better place.

Rethink Priorities is a think-and-do tank that informs nonprofits, funders and policymakers about how to most effectively improve the lives of humans and animals—both now and in the future.

Through rigorous analysis and strategic action, we identify high-leverage interventions across animal welfare, global health and development, and other neglected but promising areas. We maintain the highest standards of rigor while equally valuing curiosity and open-mindedness, working to drive evidence-based change where it's needed most.

If you'd like to support one of our fiscally sponsored projects (e.g. Epoch), you can give via Every.org, and let us know how to allocate your gift at info@rethinkpriorities.org.

Rethink Priorities

The AI Futures Project is a nonprofit research organization working to research and understand the trajectory of AI development

The **AI Futures Project** is a 501(c)(3) nonprofit research organization. We have developed a scenario forecast detailing the development of artificial general intelligence (AGI) and artificial superintelligence (ASI). Based on our research, we’ve come to believe that we might cross the thresholds to AGI and ASI within just a few years—and that plausible outcomes include unprecedented concentration of power, global catastrophe, or progress and flourishing.

The world is not ready for such a radical transformation. We hope to help policymakers, AI companies, AI entrepreneurs, AI safety researchers, and the general public to make sense of what’s coming, so they can take action and steer us in a better direction. In addition to our scenario forecast, we are developing [policy recommendations](https://time.com/collection/time100-voices/7086285/ai-transparency-measures/) and tabletop exercises (wargames) for decisionmakers.



AI Futures Project

Spritely Institute builds, researches, and standardizes networked technology which put people and communities first.


Centralized social media is harmful to society. We are building a gatekeeper-free decentralized system. Our mission is “social media done right”, to put people in control of their own identity and build the technology that would enable a shift to collaborative and intentional security models prioritizing active consent. To accomplish this, we will build a new architecture for the internet: removing the necessity of client-server architecture, replacing it with a participatory peer-centric model.

Spritely’s technology is being released as free and open source software aiming for multiple programming language implementations and eventual open standardization. All of our work, ranging from decentralized identity, peer-to-peer user agents, decentralized social networks, encrypted and portable storage, and distributed object programming infrastructure is being built to enable a gatekeeper-free path where users and content are not tied to a specific server.

Spritely Networked Communities Institute

Developing the roadmap for a sustainable, secure, and just global protein supply 🧫🌱


Check out what your support makes possible at gfi.org/your-impact. 

The Good Food Institute (GFI) is a global network of nonprofit organizations developing the roadmap for a sustainable, secure, and just protein supply. Industry alone will not meet this challenge at the scale or speed we need. GFI is accelerating the transformation of the food system by identifying solutions and mobilizing resources to make alternative proteins the default way meat is made.

GFI is a network of nonprofits around the world strategically based in the most critical economies for alternative protein advancement. In Asia, Europe, Brazil, India, Israel, and the U.S., GFI’s teams are mobilizing the international community to use markets and technology to replace harmful practices with ones that are better for the climate and biodiversity, for food security, and for global health.

GFI’s Focus
As a nonprofit, GFI is uniquely positioned to accelerate the transition to alternative proteins by focusing on three programmatic priorities:

-Cultivating a strong scientific ecosystem | GFI’s science and technology teams map out the most neglected areas that will allow alternative proteins to compete on taste and price. GFI meets these challenges by developing open-access research and resources, educating and connecting the next generation of scientists and entrepreneurs, and funding research that benefits alternative protein development across the sector. 

-Influencing policy and securing government funding | GFI’s policy teams ensure that alternative proteins are a part of the policy discussion around climate change mitigation and global health. In every region where GFI has a presence, teams advocate for government funding and incentives to transition to alternative proteins and are paving the way for the approval of novel proteins such as cultivated meat.

-Ensuring industry prioritizes alternative proteins | GFI’s corporate teams are creating a transformation of our global meat supply. GFI works to replicate past market transformations by showing companies of all sizes, from startups to multinational corporations, how alternatives to animal products can be profitable while meeting environmental, social, and governance goals.

Reimagining meat
The very real threats of climate change, global food insecurity, antibiotic resistance, and pandemics require us to imagine a different future of food. Alternative proteins are the solution that will securely and sustainably feed the world.

GFI’s global community of scientists, policy experts, and corporate specialists are creating a world where alternative proteins are no longer alternative.



The Good Food Institute

The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.

GiveWell

1067431123

Pricing

1431630327

148788709

1578280819

1675433849

1873740264

2310049938

2551237796

2595251256

281961830

2883383521

3026174861

316638097

3170054231

338811242

3705164611

3874769064

3934974605

4083678788

4124487947

4167807122

4287068530

440668958

698107245

91415239

1287028958

2729980760

3440869557

671754822

87081813

1014384873

1112422858

153399038

2028390811

220342792

2266630408

2519810400

2539558839

2826465835

We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

.css-1wjgqn{display:inline-block;--textSize:1.5rem;--lineHeight:1.7999999999999998rem;line-height:var(--lineHeight);font-size:var(--textSize);width:100%;}Research

Zig Software Foundation Inc

Zig Software Foundation Inc

Zig Software Foundation Inc

Giving Multiplier

ConnectMyVariant

Mersal Foundation for Charity and Development

Research