I believe this research is promising and it's been terribly underfunded for psychological reasons, I suppose, by philanthropists and the general public who either don't see the value or don't believes extreme life extension through better science is feasible. 

I have been following their work for years and they are one of the best charities in Egypt

Spritely Institute builds, researches, and standardizes networked technology which put people and communities first.


Centralized social media is harmful to society. We are building a gatekeeper-free decentralized system. Our mission is “social media done right”, to put people in control of their own identity and build the technology that would enable a shift to collaborative and intentional security models prioritizing active consent. To accomplish this, we will build a new architecture for the internet: removing the necessity of client-server architecture, replacing it with a participatory peer-centric model.

Spritely’s technology is being released as free and open source software aiming for multiple programming language implementations and eventual open standardization. All of our work, ranging from decentralized identity, peer-to-peer user agents, decentralized social networks, encrypted and portable storage, and distributed object programming infrastructure is being built to enable a gatekeeper-free path where users and content are not tied to a specific server.

Spritely Networked Communities Institute

Eliminating obstacles on the path to the comprehensive medical control of aging and age-related disease.

Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.

Longevity Escape Velocity Foundation

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

ALLFED aims to increase the resilience of the world's food systems to global catastrophic food shocks.

The mission of Alliance to Feed the Earth in Disasters (ALLFED) is to help build resilience to global catastrophic food system failure.

ALLFED seeks to provide practical, affordable, and resilient food solutions so that, in the event of a global catastrophe, governments, industry, and communities can respond quickly and distribute food equitably, saving lives and promoting the continuation of global cooperation.

However, ALLFED currently faces a major funding gap. **We have had to scale back our programs and, without new funding, will need to continue cutting half of our budget in 2026**. This will mean continuing to significantly scale down our programs, including our research output and the ability to support governments in preparing for global food system shocks.

We focus on events, such as large volcanic eruptions, pandemics, and cyberattacks, which could deplete 5% or more of global calorie output, or access to those calories. In such events, the loss of food would likely kill far more people than the catastrophe itself directly.

“Resilient food solutions'' are what ALLFED calls the foods, technologies, and systems that could help everyone survive global catastrophic food failure. ALLFED’s ultimate goal is to feed everyone, no matter what.

ALLFED Institute (Alliance to Feed the Earth in Disasters)

Providing strategic legal response to protect human rights and defend freedoms

Chapter Four Uganda is an independent a non-profit organisation working to defend civil liberties and promote human rights for all. 

Established in 2013, the organisation works in the courts, legislature and communities to provide bold and innovative legal response through strategic and public interest litigation, first line legal representation, human rights research and documentation, legislative and strategic advocacy, and general counsel support. We work with human rights defenders, pro-democracy actors and civil society organisations - with keen focus on the most vulnerable, underrepresented, and discriminated sections of the society. 

Over the past decade, Chapter Four has grown into a dependable source of integrity, purposeful public interest, and an impartial advocate for justice for all no matter their world view, social, political leaning, or sexual orientation/gender identity. 

Chapter Four Uganda

Allies Against Slavery builds platforms and partnerships that accelerate data-driven solutions to human trafficking. 

Human trafficking is a hidden problem that thrives in the shadows of society. Myths and misconceptions are pervasive, and data is unreliable. As a result, victims aren’t identified, traffickers aren’t prosecuted, and solutions aren’t data-informed or well-coordinated.

But that is changing. Allies Against Slavery harnesses data to illuminate and eradicate human trafficking. Our tools help allies in the fight to identify victims, coordinate care, and take informed action. 

Our vision is clear: to ensure that every community across the United States has the data it needs to combat and prevent human trafficking. But we cannot achieve this vision alone. We need to leverage innovative, data-driven solutions and forge crucial partnerships to shine a light on trafficking and build a future where freedom and dignity are secured for all. We invite you to join us in this important mission.

Allies Against Slavery

Exploring and supporting meaningful, impactful medical careers.

Through [High Impact Medicine](https://www.highimpactmedicine.org/), we are broadening the medical community’s conceptualisations of what it means to pursue medicine’s ultimate aim – to help others. 

We support medical students and doctors from all around the world who want to increase their positive impact by fostering a global community that connects them with relevant knowledge, people, and opportunities. 

High Impact Medicine Limited is an England and Wales private limited company operating through a fiscal sponsorship with Players Philanthropy Fund, Inc. a Texas nonprofit corporation recognized by IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178, [ppf.org/pp](https://ppf.org/pp)). Contributions to High Impact Medicine qualify as tax-deductible to the fullest extent of the law.

High Impact Medicine

A research nonprofit that works on assessing whether cutting-edge AI systems could pose catastrophic risks to society.

METR (Model Evaluation and Threat Research) builds the science of accurately assessing risks, so that humanity is informed before developing transformative AI systems.

We believe that AI could change the world quickly and drastically, with potential for both enormous good and enormous harm. We also believe it’s hard to predict exactly when and how this might happen.

At some point, AIs will probably be able to do most of what humans can do, including developing new technologies; starting businesses and making money; finding new cybersecurity exploits and fixes; and more.

We think it’s very plausible that AI systems could end up pursuing goals that are at odds with a thriving civilization. This could be due to someone’s deliberate effort to cause chaos, or happen despite the intention to only develop AI systems that are safe.

Given how quickly things could play out, we don’t think it’s good enough to “wait and see” whether there are dangers.

We believe in vigilantly, continually assessing risks. If an AI brings significant risk of a global catastrophe, the decision to develop and/or release it can’t lie only with the company that creates it.

METR

Help preserve the Shulgin legacy and build a global community dedicated to scientific, therapeutic, and spiritual insight.

The Shulgin Foundation honors the revolutionary legacy of Ann and Sasha Shulgin while building a vibrant future for psychedelic science, healing, and community.

From an unassuming 200-square-foot lab in Lafayette, California, Sasha Shulgin created over 150 novel psychedelic compounds, including MDMA, while Ann pioneered therapeutic frameworks that continue to guide modern psychedelic therapy. Their historic Farm—a gathering place for four decades of psychedelic research and community—stands as both a monument and a living laboratory.

Today, the Foundation is preserving this irreplaceable heritage site while fostering a global community dedicated to scientific discovery, therapeutic advancement, and spiritual exploration. Through educational programs, archival preservation, and community gatherings, we are carrying forward the Shulgins' vision of responsible inquiry and compassionate care.

Your tax-deductible donation supports:

- Preserving the historic Shulgin Farm property
- Creating accessible psychedelic education
- Archiving invaluable research materials
- Building community across generations of researchers and healers

Join us in honoring the past while creating the future of psychedelic science and healing.

Shulgin Foundation

We match donations to any charity you choose while introducing you to super-effective charities. Learn more: GivingMultiplier.org

[**Giving Multiplier**](https://givingmultiplier.org) is a research project created at Harvard University that adds matching funds to any charity of your choice while introducing donors to highly effective charities recommended by experts.

*Resources:*

- [Make a donation that gets matched](https://givingmultiplier.org)
- [Become a matching funder](http://givingmultiplier.org/matching) (Donations made on this page will also go toward our matching system.)
- [Sign up to our newsletter](http://eepurl.com/i0GHhc)
- [Learn about our philosophy](https://givingmultiplier.org/philosophy)

Questions? Email us: **info@givingmultiplier.org**

Giving Multiplier

Invest in Linköping University's continued development 
 

Linköping University's Anniversary Foundation (in Swedish called "Jubileumsstiftelsen") functions as a guarantor with the aim of developing free and competitive research as well as continuous and relevant education of the highest quality. Among other things, the foundation has been designed so that donors can direct funds to special purposes at Linköping University (LiU) without creating their own foundation. It has proven to be a good alternative for donations as the foundation already successfully manages funds from donors who, out of self-interest, have donated funds to specific purposes. It is also possible to donate "free funds" to the "Jubileumsstiftelsen", which is aimed at prioritized purposes for the future.  

It started with a vision
A university is never finished, must never stagnate. Its business must be constantly evolving and changing. LiU is still a young university with a strong ambition to establish itself in the long term as an internationally recognized university for higher education, research and utilization. With that knowledge, the founders behind the initiative, together with LiU, saw a vision of a foundation as a long-term guarantor for the university's continued development. In connection with LiU's 40th anniversary, in 2015, the municipalities of Linköping and Norrköping and the Östergötland Region took the initiative to make a donation of SEK 1 million to Linköping University, to establish and fulfill the vision – "Jubileumsstiftelsen". 

In close collaboration with the business world and society, Linköping University (LiU) conducts world-leading, boundary-crossing research in fields including materials science, IT and hearing.  In the same spirit, the university offers many innovative educational programmes, many of them with a clear vocational focus, leading to qualification as, for example, doctors, teachers, economists and engineers. 

The university has 36 000 students and 4,300 employees on four campuses. Together we seek answers to the complex questions facing us today. Our students are among the most desirable in the labour market and international rankings consistently place LiU as a leading global university. 

LiU achieved university status in 1975 and innovation is our only tradition.

Alternative ways to give:
For gifts by check: Write your check to KBFUS, write "Linkoping University Anniversary Foundation US" in the memo section of the check, and send it to KBFUS, 551 Fifth Avenue, Suite 2400, New York, NY 10176.

Gifts by wire transfer or to contribute other types of property: Email KBFUS at: info@kbfus.org or phone (212) 713 7660.

Linkoping University Anniversary Foundation

Zig is a general-purpose programming language and toolchain for maintaining robust, optimal, and reusable software.

The Zig Software Foundation is a non-profit corporation founded in 2020 by Andrew Kelley, the creator of Zig, with the goal of supporting the development of the language. Currently, the ZSF is able to offer paid work at competitive rates to a small number of core contributors. We hope to be able to extend this offer to more core contributors in the future.

Zig Software Foundation Inc

Aquatic Life Institute is a 501(c)(3) non-profit focused on reducing the suffering of aquatic animals in the global food system.

Aquatic Life Institute (ALI) was founded in 2019 to address the critical and often overlooked issue of aquatic animal welfare. Recognizing that aquatic animals are the most exploited group of animals worldwide yet remain largely unprotected, ALI set out with a mission to drive systemic change and elevate aquatic animal welfare as a priority in global food systems.

Our theory of change is rooted in the belief that by influencing key stakeholders and decision makers, advancing policies, and fostering collaboration, we can drive systemic transformation for billions of aquatic animals. 

Building on this foundation, ALI has emerged as a thought leader, advocating for tangible improvements across the seafood supply chain. By engaging with key stakeholders, including corporations, certification schemes, and policymakers, we work to ensure that aquatic animals trapped in the food system receive the attention they deserve in decision-making processes relating to sustainability and food systems. 

ALI’s work is driven by evidence-based strategies and collaboration. This approach has earned ALI widespread recognition, including a 2024 Top Charity recommendation from Animal Charity Evaluators (ACE). This endorsement solidifies ALI’s position as one of the most effective organizations in the world advancing aquatic animal welfare. 

Aquatic Life Institute Inc

Developing the roadmap for a sustainable, secure, and just global protein supply 🧫🌱


Check out what your support makes possible at gfi.org/your-impact. 

The Good Food Institute (GFI) is a global network of nonprofit organizations developing the roadmap for a sustainable, secure, and just protein supply. Industry alone will not meet this challenge at the scale or speed we need. GFI is accelerating the transformation of the food system by identifying solutions and mobilizing resources to make alternative proteins the default way meat is made.

GFI is a network of nonprofits around the world strategically based in the most critical economies for alternative protein advancement. In Asia, Europe, Brazil, India, Israel, and the U.S., GFI’s teams are mobilizing the international community to use markets and technology to replace harmful practices with ones that are better for the climate and biodiversity, for food security, and for global health.

GFI’s Focus
As a nonprofit, GFI is uniquely positioned to accelerate the transition to alternative proteins by focusing on three programmatic priorities:

-Cultivating a strong scientific ecosystem | GFI’s science and technology teams map out the most neglected areas that will allow alternative proteins to compete on taste and price. GFI meets these challenges by developing open-access research and resources, educating and connecting the next generation of scientists and entrepreneurs, and funding research that benefits alternative protein development across the sector. 

-Influencing policy and securing government funding | GFI’s policy teams ensure that alternative proteins are a part of the policy discussion around climate change mitigation and global health. In every region where GFI has a presence, teams advocate for government funding and incentives to transition to alternative proteins and are paving the way for the approval of novel proteins such as cultivated meat.

-Ensuring industry prioritizes alternative proteins | GFI’s corporate teams are creating a transformation of our global meat supply. GFI works to replicate past market transformations by showing companies of all sizes, from startups to multinational corporations, how alternatives to animal products can be profitable while meeting environmental, social, and governance goals.

Reimagining meat
The very real threats of climate change, global food insecurity, antibiotic resistance, and pandemics require us to imagine a different future of food. Alternative proteins are the solution that will securely and sustainably feed the world.

GFI’s global community of scientists, policy experts, and corporate specialists are creating a world where alternative proteins are no longer alternative.



The Good Food Institute

The Vision of the EWT is a healthy planet and an equitable world that values and sustains the diversity of all life.

The EWT is among South Africa’s largest and
most established national non-governmental
conservation organizations.  Founded in 1973, we are a non-profit organization with an expanding footprint
throughout southern and East Africa, focusing
on conserving threatened species and ecosystems to the benefit of people. We achieve this by conducting on-the-ground research, supporting community-led conservation, training and building capacity, addressing human-wildlife conflict, monitoring threatened species, and establishing safe spaces for wildlife range expansion.

The EWT works with key partners, including
communities, businesses, landowners, academic
institutions, and governments, to create a
sustainable future for wildlife and people.
 The Endangered Wildlife Trust is dedicated to
conserving threatened species and ecosystems in southern and East Africa to the benefit of all.

The EWT achieves this mission by delivering on
three strategic imperatives: Saving species,
conserving habitats, and benefiting people.
OUR STRATEGY
Our conservation programmes form the
organization’s backbone, harnessing the talent
and enthusiasm of a dynamic team of
individuals whose unique exper􀆟se and
mo􀆟va􀆟on provide them with the tools to
respond to the challenges they face in pursuit
of saving our most threatened species and
ecosystems.
The EWT is a registered Trust governed in accordance with the Trust Property Control Act No. 57 of 1988, under Master’s reference number IT 6247. The EWT is also registered in South Africa as a Non-Profit Organisation, registration number 015- 502 NPO
and Public Benefit Organisation, registration number 930 001 777

SPECIES RECOVERY
The EWT has achieved remarkable gains for many species, where downward trends in the local populations of Wattled and Grey Crowned Cranes, Piggersgill’s Frogs, the Amathole Toad, and the Riverine Rabbit have joined the Cheetah as species on a pathway to recovery. Critically Endangered
Wattled Cranes are increasing in number, now estimated at some 320 birds nationally, up 60% from their lowest numbers. The EWT has also helped reverse the decline of Endangered Grey Crowned Cranes, while Blue Crane numbers have increased from an estimated 25,500 birds nationally in 2007 to some 30,000 birds today.
SPACE FOR SPECIES
Through our range expansion work, we have secured and protected safe spaces for multiple species to thrive and we have reintroduced many threatened species back into secure and suitable landscapes. Safe space for African Wild Dogs has increased to over 1.4 million ha throughout southern Africa and their numbers and generic health have followed suit. Safe space for Cheetahs and their numbers have also increased from 217 Cheetahs on 41 reserves in South Africa in 2011, to 470 Cheetahs on 65 reserves covering over two million hectares across southern Africa.

SAFEGUARDING OUR SPECIES
To protect threatened species, we monitor them and work with partners, businesses, landowners, and communities to reduce the threats they face. We are innovating to achieve bigger impacts, as evident in our drone project’s expansion to use drones to mark power lines - reducing bird strikes safely and affordably and monitor Southern Right Whales in a way that wasn’t possible before. We continue to explore the use of eDNA to identify the presence of elusive and potentially extinct species, such as
Van Zyl’s and De Winton’s Golden Moles, so that action can be taken to save the last of their habitats.

Our pioneering Eye in the Sky carcass and wildlife poisoning detection project has already saved thousands of animals from secondary poisoning as a result of its efficient and effective success and our quick response times. The project uses the movements and behavior patterns of GPS-tracked vultures to remotely detect potential poisoning events and respond to these rapidly, alerting rangers on the ground and preventing further loss of wildlife to poisoning. We also contribute to preventing wildlife crime through the deployment of Conservation K9s to detect wildlife contraband and track poachers. These dogs help us to protect species, including rhinos, elephants, and pangolins.

Protec􀆟ng and conserving natural places is one of the most important strategies for comba􀆫ng the effects of
biodiversity loss and climate change. The EWT conserves habitats by reducing habitat loss and improving the
ecological integrity of threatened ecosystems through rehabilita􀆟on, restora􀆟on, and sustainable land
management. Many of the EWT’s programmes are involved in habitat conservation, but two are dedicated to protecting specific habitats.

COLLABORATING FOR CONSERVATION
An effective vehicle for conserving habitats is the formal protection of land through Biodiversity Stewardship. We work with private and community landowners to legally declare their land as protected or help them to manage it sustainably and without damage to sensitive species and ecosystems.
The EWT was instrumental in the development of Biodiversity Stewardship, having facilitated the workshops which led to its establishment, and subsequently, the EWT has declared 185 properties (over 139,000 ha) as protected areas in the last
ten years and is currently in the process of securing a further 130,000 hectares for threatened species conservation across South Africa. This includes proper􀆟es in one of the region’s most important centres of endemism: the Soutpansberg Mountain Range. Easily recognized for our work to safeguard charisma􀆟c species like the Wild Dog and Cheetah, the EWT also played a key role in preventing the extinction of the Brenton Blue Butterfly by establishing a dedicated reserve for this endemic insect.  Other critical habitats have been protected to prevent the extinction of many smaller, lesser-known species, including rep􀆟les, amphibians, butterflies, golden moles, and threatened plants.

CARBON FOR CONSERVATION
After establishing the feasibility of carbon trading in South Africa’s grasslands and recognizing the potential benefits for farmers and grassland and wetland management, the EWT the EWT initiated the first carbon offsetting contracts with private landowners in South Africa, in the Drakensberg.
When landowners agree to conserve and manage their land to allow for the verifiable sequestration of carbon in the soil, the carbon can be converted into carbon credits. Liable ensures, usually big carbon emitters, can purchase up to 10% of their carbon as carbon credits to reduce their tax liability in South Africa. These purchases create a long-term revenue stream for farmers and conservation organizations to support conservation efforts and protect important habitats through improved land-use management.

People need nature to survive – it provides important resources we depend on. We must live in harmony
with nature to thrive in healthy ecosystems that will support us and future genera􀆟ons, our wildlife, and
maintain our rich natural and cultural heritage. Through two of its programmes, the EWT implements
innovative strategies that incorporate the needs of people and the environment to ensure that people
benefit from the more sustainable use of natural resources.
BENEFITTING PEOPLE
CAPACITY FOR CONSERVATION
Working across diverse landscapes such as wetlands,
grasslands, river catchments, savannahs, and mountains, the EWT has embraced the need to support the lives and livelihoods of thousands of people who depend on their local environment, from developing sustainable livelihoods as alternatives to environmentally destructive practices in communities from KwaZulu-Natal to Limpopo, Zambia, and as far as Uganda, to pioneering the implementation of Population, Health and Environment in communities in southern and East Africa to support sustainable communities and empower women. The EWT
promotes and implements the education of school
learners and builds capacity for conservation and
ecotourism in communities across our project areas.

BIODIVERSITY AND BUSINESS
Recognizing the importance of biodiversity to business, the EWT established the National Biodiversity and Business Network (NBBN) in 2013 to work with innovative businesses to identify and manage the risks and opportunities resulting from their interactions with the natural world. Through its Biodiversity Disclosure Project, the NBBN helps companies to understand, measure, and disclose their biodiversity impacts and policies. The NBBN introduced the world’s first standardized accounting
framework, the Biological Diversity Protocol (BDP), which measures a business’ impact on biodiversity and identifies areas of improvement over time.  The EWT’s targeted conservation work has national and global impacts and our achievements contribute to multiple conservation-related frameworks. These include South Africa’s 2nd National Biodiversity Strategy and Action Plan (2015–2025), and the National Biodiversity Assessment which assess the status of, and identify the biodiversity and ecosystem
management priori􀆟es as well as the International Union for Conservation of Nature (IUCN) Red List of Threatened Species. 

Arguably, the EWT’s most important global impact is our work toward achieving the Sustainable Development Goals (SDGs), a collection of 17 interlinked global goals designed by the United Nations. The SDGs are a universal set of goals, targets, and indicators that UN member states should use to frame their agendas and political policies. Ambitious by nature, they are a government-led endeavor that serves to coordinate actions by United Nations agencies, businesses, non-governmental groups, and any other entities working on specific goals. These are
the goals that the EWT contributes to.



Endangered Wildlife Trust

The AI Futures Project is a nonprofit research organization working to research and understand the trajectory of AI development

The **AI Futures Project** is a 501(c)(3) nonprofit research organization. We have developed a scenario forecast detailing the development of artificial general intelligence (AGI) and artificial superintelligence (ASI). Based on our research, we’ve come to believe that we might cross the thresholds to AGI and ASI within just a few years—and that plausible outcomes include unprecedented concentration of power, global catastrophe, or progress and flourishing.

The world is not ready for such a radical transformation. We hope to help policymakers, AI companies, AI entrepreneurs, AI safety researchers, and the general public to make sense of what’s coming, so they can take action and steer us in a better direction. In addition to our scenario forecast, we are developing [policy recommendations](https://time.com/collection/time100-voices/7086285/ai-transparency-measures/) and tabletop exercises (wargames) for decisionmakers.



AI Futures Project

Supporting research on the welfare of neglected animals.

There are millions of known arthropod species. There are doubtless millions more. And there may be quintillions of individual arthropods.

We know little about most of these animals and, as a result, little about how their welfare might be improved in contexts where humans use, manage, or otherwise affect them.

The mission of the Arthropoda Foundation is to support research on the welfare of arthropods. We value both basic and applied projects. We are particularly interested in research with a clear path to impact, whether by shaping future science or informing real-world decision-making.

Arthropoda Foundation

MAPS works towards a post-prohibition world by advancing research, changing policies, and shaping culture. 

Since our founding in 1986, the Multidisciplinary Association for Psychedelic Studies (MAPS) has been the leading organization building the movement to foster evidence-based approaches to psychedelics and the people who use them. When used safely and responsibly, psychedelics have the potential to promote personal growth and well-being and treat various mental health conditions. Three pillars guide our efforts: advancing research, changing policies, and shaping culture. 

[Advancing Research](https://maps.org/advancing-research/)

MAPS spent decades developing MDMA-assisted therapy for the clinical utilization of psychedelic-assisted therapies. With the road paved for the next generation of research and drug development, MAPS now stewards the research landscape we helped cultivate.

We are dedicated to fostering new research directions that prioritize public benefit, supporting international researchers and pilot programs, and ensuring the accessibility and culturally appropriate integration of psychedelics as a tool for individual and community wellness. We center research that contributes to knowledge in the public domain.

[Changing Policy](https://maps.org/changing-policy/)

The cultivation, use, and trade of psychoactive substances — including psychedelics — has been a consistent aspect of human history, but prohibition, criminalization, and militarization — and their inherent oppression — have led to drastic consequences. The ongoing, global War on Drugs has been justified by bad science, racism, and fear for too long: it has led to mass incarceration; erosion of civil liberties; ecological damage; economic waste; and the public health polycrisis of adulteration, poisoning, and overdose. Many of these harmful effects have disproportionately impacted the most historically exploited and oppressed communities. Consequently, we believe societies worldwide have an obligation to account for and repair those harms, to the extent possible. 

MAPS envisions a post-prohibition future based on Consciousness, not Criminalization.

[Shaping Culture](https://maps.org/shaping-culture/)

For psychedelics to be most safely integrated into society, we need to be honest about the implications. MAPS recognizes the importance of a comprehensive understanding of their risks and potential benefits, teaching people how to navigate altered states of consciousness and how policies impact individuals and communities. 

We create cutting-edge education for professionals and the public, provide expert support for the psychedelic and drug policy movement, and convene people who share our vision—all to lay the groundwork and create the guardrails necessary for responsible social transformation. 

As psychedelics become more mainstream and an increasing number of people seek to use them for healing and personal growth, we are more dedicated than ever to making resources available for people and communities to safely and responsibly integrate psychedelics into medical, legal, and spiritual contexts.

MAPS

IBB equips individuals across the Middle East with the information, skills, and resources to build a free &more prosperous future


We partner with people across the region to make vital and often banned information accessible in Arabic, Dari, Pashto and Kurdish. We certify each of our translators to produce and distribute content on topics like critical thinking, civil rights, science, and pluralism. We also place trust and resources into the hands of people across MENA who are forging sustainable paths to prosperity through entrepreneurship.




Ideas Beyond Borders

Delivering unconditional cash directly to the world's poorest households via secure mobile transfers. 

Since 2009, GiveDirectly has delivered more than $1 billion in unconditional cash transfers directly into the hands of 2+ million people living in poverty. These one-time cash transfers allow recipients to invest in what they need most and have been shown to improve their earnings, children’s school attendance, health, nutrition, and mental well-being.
 
GiveDirectly uses government data to target villages where most or all residents are living in extreme poverty, defined by the World Bank as earning under $3/day. In-country GiveDirectly staff enroll each household in a village to receive a large lump sum transfer of \~$1,000 USD using mobile money. Recipients can then use the funds to invest in what they need – whether it’s on starting a business, education, repairing their home, healthcare, livestock, or anything else.
 
GiveDirectly also uses rigorous experimental research (including randomized controlled trials) to measure the impact of their cash programs, answer public policy questions, and generate evidence on key design and implementation questions.

GiveDirectly

We defend your civil liberties in a digital world.

The first line of defense when your rights in the digital world come under attack. EFF champions user privacy, free expression, and innovation through impact litigation, policy analysis, grassroots activism, and technology development. We work to ensure that rights and freedoms are enhanced and protected as our use of technology grows.

Electronic Frontier Foundation (EFF)

Alcor is the world’s leader in cryopreservation research. Established in 1972, we are a non-profit scientific research foundation.

**Our Mission**

To save lives through the following prioritized principles:

1. Maintain the current patients in biostasis.
2. Place current and future members into biostasis (when and if needed).
3. Eventually restore to health and reintegrate into society all patients in Alcor’s care.
4. Fund research into developing more cost effective and reliable means for 1-3 above.
5. Provide public education as a means of fostering growth to support the goals of 1, 2, 3, 4 above.

Alcor Life Extension Foundation

Founders Pledge is a global nonprofit empowering entrepreneurs to do the most good possible with their charitable giving. 

Maximize your philanthropic impact with Founders Pledge. We empower a global community of over 2,100 members, equipping them with everything needed to give effectively: from evidence-led research and expert advice on the world's most pressing problems to comprehensive infrastructure for seamless global grant-making, and a powerful network for collaboration. Together, we've already channeled over $1.5 billion to high-impact causes globally, tackling critical issues like climate change, global health, and emerging existential risks. 

When you donate through every.org today, you're joining this proven movement, and our unique funding model ensures 100% of your contribution goes directly to charity, as our operational costs are generously covered by a dedicated community of philanthropists.

Donate this Giving Season and we'll match your donation up to a value of $750,000, until Dec 31.

Founders Pledge

The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

ARC is a non-profit research organization whose mission is to align future machine learning systems with human interests. 

See our website for more info about our work. 

Alignment Research Center

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.

GiveWell

148788709

1578280819

1873740264

188270313

2052641908

2088874155

We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

Choose a donation for Every.org

2140519340

2249891241

2310049938

2551237796

2576076625

2594001433

283252266

2883383521

316638097

3221010034

338811242

3705164611

3842241318

3934974605

4167807122

506613571

977532837

1287028958

1858760411

2729980760

2939442496

3440869557

671754822

87081813

1014384873

1112422858

153399038

2028390811

220342792

2266630408

2519810400

2539558839

2826465835

2843798242

2898624300

3259439560

339774024

3642494300

3902459442

4250940449

472232120

585491400

641510716

91682487

Effective Altruism https://www.astralcodexten.com/p/the-pledge