Thanks very much to Epoch AI for all of the research you're doing into AI. I'm fascinated by the rapid advancements into AI and your website provides very clear information. 

Just another very small donation to show my appreciation for all of the interesting information you have on AI.

Michael cares deeply about humans, and he sees patterns at a scale most of us don’t. With Humans on the Loop he is putting much-needed energy into ensuring we retain agency as we’re absorbed into complex technological systems

I know enough about biology and genetics to be sure that Aubrey de Grey's approaches have huge merit, and potential of becoming a reality.  I also believe in what LEVF is doing, by doing and funding the research required that may not be otherwise easy to get investments or grants for.  But it's needed to further the reversing ageing approach.  Kudos!

GiveWell, more than any organization I know, works tirelessly to find the most cost effective ways to save and improve lives. This simple idea is deeply powerful!

Epoch AI is a research institute investigating key trends and questions that will shape the trajectory and governance of AI.

Epoch AI is a leading research institute that develops public knowledge on AI's trajectory through rigorous research, novel benchmarking, and comprehensive data tracking. We seek general support to expand our work informing policymakers, industry leaders, and society on AI development and its implications. Our unique position combining technical depth with accessible communication has made us a trusted source for stakeholders ranging from government officials to tech leaders.

Broadly, our mission is to conduct and disseminate rigorous research on the trajectory and impact of artificial intelligence, to enable better policy and decision-making. With additional funding, we aim to expand three key initiatives:

1. Data Curation: Building on our successful AI model and hardware tracking to cover AI clusters and companies, launching weekly data insights for timely analysis.
2. Capability Measurement: Growing our AI Benchmarking Hub through independent model evaluations and novel benchmarks like FrontierMath.
3. Economic Modeling: Developing a framework combining AI scaling laws with growth theory to analyze automation impacts and compute scaling.

We'll achieve these through strategic hiring of technical talent, maintaining our commitment to rigorous analysis, and expanding our successful track record of creating accessible, high-impact content.

If you would like to arrange a grant agreement or conduct due diligence before donating, please reach out to us via donate@epoch.ai

Epoch AI

Zig is a general-purpose programming language and toolchain for maintaining robust, optimal, and reusable software.

The Zig Software Foundation is a non-profit corporation founded in 2020 by Andrew Kelley, the creator of Zig, with the goal of supporting the development of the language. Currently, the ZSF is able to offer paid work at competitive rates to a small number of core contributors. We hope to be able to extend this offer to more core contributors in the future.

Zig Software Foundation Inc

Let's dream together better!  Exploring wisdom for a world of magical technologies with paleontologist-futurist Michael Garfield.

**If you could do anything with technology, what will you do?**

Humans On The Loop is a transdisciplinary inquiry into the nature of agency in our age of automation.

In our AI-infused society, the gap between imagination and “reality” is smaller than it’s ever been — and now it’s time for humankind to graduate from asking if our dreams are possible to asking how we can dream better. This means cultivating deeper self-awareness, more discipline and humility, and a better metaphysics of technology to help us wield these new superpowers. But decades into a period of rapid information scaling, our grasp of consensus reality and executive function have eroded, causing an epistemic crisis. The wicked problems of this century require coordination at unprecedented scale, but our greatest natural resource — attention — has worn even thinner than our topsoil. How do we regenerate it and restore the faculties we need to be good stewards of this new ecology of minds?

Navigating the challenges that come with new information technologies is a group exercise and demands inherently plural approaches. The right response to tools that amplify our biases is to lean in with curiosity and play, not fearI have spent two decades studying and synthesizing  perspectives on intelligence and technology, innovation, and human-technology co-evolution…as well as testing bleeding-edge creative tools in public, helping cultivate systems literacies for navigating transformation, and fostering a massive network of mentors and collaborators with whom I share a devotion to the cultivation of a healthy Biosphere and Technosphere. As AI comes of age, this is the moment to recruit as many of them as we can into a multimodal public inquiry on wisdom and technology, power and responsibility, holistic practices for cultivating saner futures…and how we can keep Humans On The Loop and at the wheel.

It's going to be a trip — how can we make sure that it’s a good one?

This project exists to foster a renaissance of collaboration and the conditions for new ways of knowing. Its goals include to:

– Boost public discourse at the intersection of technology and wisdom
– Create a legacy of public goods that help train instruments for deepening our understanding
– Prototype and demonstrate experimental tools for thought
– Promote the adoption of reflexive AI for both private and public good
– Help map the emergent ecosystem of changemaking orgs and wise innovators
– Fertilize new narratives and strategies for navigating "wicked problems"
– Bridge domains and cultures in positive-sum collaboration

***Explore this project's [vision document](https://docs.google.com/document/d/1kIoDlRD721UhZW4SjXIeccpCo2-v3ngoF1iZDwNyfPU/edit?usp=sharing), [pitch deck](https://bit.ly/hotl-slideshow), and* [essay/podcast archive](https://michaelgarfield.substack.com/t/humans-on-the-loop)*.***
***[Subscribe](https://michaelgarfield.substack.com/subscribe) for weekly dialogues plus articles, reviews, monthly hangouts, and more.* And please** [email my secure inbox](mailto:humansontheloop@proton.me) **with questions or partnership requests!**

Humans On The Loop

Spritely Institute builds, researches, and standardizes networked technology which put people and communities first.


Centralized social media is harmful to society. We are building a gatekeeper-free decentralized system. Our mission is “social media done right”, to put people in control of their own identity and build the technology that would enable a shift to collaborative and intentional security models prioritizing active consent. To accomplish this, we will build a new architecture for the internet: removing the necessity of client-server architecture, replacing it with a participatory peer-centric model.

Spritely’s technology is being released as free and open source software aiming for multiple programming language implementations and eventual open standardization. All of our work, ranging from decentralized identity, peer-to-peer user agents, decentralized social networks, encrypted and portable storage, and distributed object programming infrastructure is being built to enable a gatekeeper-free path where users and content are not tied to a specific server.

Spritely Networked Communities Institute

Eliminating obstacles on the path to the comprehensive medical control of aging and age-related disease.

Longevity Escape Velocity (LEV) Foundation exists to conduct and inspire research to proactively identify and address the most challenging obstacles on the path to the widespread availability of comprehensively effective treatments to prevent and reverse human age-related disease.

Longevity Escape Velocity Foundation

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

LASST is a nonprofit dedicated to using legal advocacy to make advances in science and technology safer for people and the planet.

LASST works through US courts and public advocacy to help push the development of emerging science and technology in a positive direction. We focus primarily on mitigating catastrophic risks from advanced artificial intelligence systems and biotechnology, but we pride ourselves on being practical and responsive. 

***What we've been up to:***

Public advocacy on AI 

- We helped organize the [Not For Private Gain](https://notforprivategain.org/) advocacy coalition, advocating to the Attorneys General of California and Delaware to protect OpenAI’s charitable mission (ensuring artificial general intelligence is safe and benefits all of humanity) from being undermined by the company’s corporate restructuring. Our work helped convince OpenAI to back off its original restructuring proposal and commit to continued nonprofit control, and we continue to advocate for even better outcomes from a safety perspective. 
- We dug into the [corporate filings of xAI](https://lasst.org/2025/08/25/xai-and-public-benefit-corporations-in-ai/), [revealing](https://www.cnbc.com/amp/2025/08/25/elon-musk-xai-dropped-public-benefit-corp-status-while-fighting-openai.html) that despite what it has said to at least one court and the public, it is no longer a public benefit corporation. The revelation shows that AI companies organizing as PBCs (including OpenAI) is not a robust way to ensure safe AI systems.

Developing and filing amicus briefs

- We pulled together a coalition of respected virologists, epidemiologists and public health professionals to file [amicus](https://lasst.org/2024/12/23/lassts-pathogen-research-amicus-brief-project/) [briefs](https://drive.google.com/file/d/1pb7vB6yblM7Yj-219tb-g2lkDvWLgggm/view?usp=drive_link) in COVID-origins litigation advocating for outcomes that will deter irresponsibly dangerous research involving pathogens with enhanced pandemic potential.  
- We helped write [the amicus brief Encode filed in the Musk v. Altman litigation](https://encodeai.org/encode-backs-legal-challenge-to-openais-for-profit-switch/), reframing OpenAI’s restructuring as a public interest AI safety issue and catalyzing anti-restructuring public advocacy work. 

Litigation surveillance and research 

- We track what courts are doing on AI and biosafety so we can better advocate in the context of evolving case law (like *Mobley v. Workday*’s holding on deployer liability for the actions of AI agents or *Garcia v. Character Technologies* addressing whether the First Amendment protects chatbot outputs). This helps us find cases where amicus briefs can help influence key judicial decisions or new precedents can be incorporated into impact litigation interventions.
- We’re always doing fact research designed to support legal interventions, including filing public records requests under FOIA and state analogs.

Legal Advocates for Safe Science and Technology (LASST)

**Every child deserves the chance to thrive.**
In Malawi, 1 in 18 children has a disability — yet most never receive the care or support they need. At Fount for Nations, we believe every child is whole, worthy, and full of potential.

Your gift helps us:

- **Screen children early** so delays are caught and treated.
- **Provide therapy & care** through our Family Centre and community programs.
- **Empower families & champions** to advocate for inclusion.

Together, we’re building a Malawi where every child is seen, supported, and included.

*Your donation doesn’t just fund programs — it changes a child’s story.*

Fount for Nations (FFN)

Allies Against Slavery builds platforms and partnerships that accelerate data-driven solutions to human trafficking. 

Human trafficking is a hidden problem that thrives in the shadows of society. Myths and misconceptions are pervasive, and data is unreliable. As a result, victims aren’t identified, traffickers aren’t prosecuted, and solutions aren’t data-informed or well-coordinated.

But that is changing. Allies Against Slavery harnesses data to illuminate and eradicate human trafficking. Our tools help allies in the fight to identify victims, coordinate care, and take informed action. 

Our vision is clear: to ensure that every community across the United States has the data it needs to combat and prevent human trafficking. But we cannot achieve this vision alone. We need to leverage innovative, data-driven solutions and forge crucial partnerships to shine a light on trafficking and build a future where freedom and dignity are secured for all. We invite you to join us in this important mission.

Allies Against Slavery

We match donations to any charity you choose while introducing you to super-effective charities. Learn more: GivingMultiplier.org

[**Giving Multiplier**](https://givingmultiplier.org) is a research project created at Harvard University that adds matching funds to any charity of your choice while introducing donors to highly effective charities recommended by experts.

*Resources:*

- [Make a donation that gets matched](https://givingmultiplier.org)
- [Become a matching funder](http://givingmultiplier.org/matching) (Donations made on this page will also go toward our matching system.)
- [Sign up to our newsletter](http://eepurl.com/i0GHhc)
- [Learn about our philosophy](https://givingmultiplier.org/philosophy)

Questions? Email us: **info@givingmultiplier.org**

Giving Multiplier

Delivering unconditional cash directly to the world's poorest households via secure mobile transfers. 

Since 2009, GiveDirectly has delivered more than $1 billion in unconditional cash transfers directly into the hands of 2+ million people living in poverty. These one-time cash transfers allow recipients to invest in what they need most and have been shown to improve their earnings, children’s school attendance, health, nutrition, and mental well-being.
 
GiveDirectly uses government data to target villages where most or all residents are living in extreme poverty, defined by the World Bank as earning under $3/day. In-country GiveDirectly staff enroll each household in a village to receive a large lump sum transfer of \~$1,000 USD using mobile money. Recipients can then use the funds to invest in what they need – whether it’s on starting a business, education, repairing their home, healthcare, livestock, or anything else.
 
GiveDirectly also uses rigorous experimental research (including randomized controlled trials) to measure the impact of their cash programs, answer public policy questions, and generate evidence on key design and implementation questions.

GiveDirectly

We are a global think tank  breaking down barriers to systems change - focused on Gender and AI to to leave no one behind.

**WOMEN AT THE TABLE** is the first organization to focus on systems change by helping feminists gain influence in sectors that have key structural impact: the economy, democracy and governance, technology and sustainability. As a pioneering think tank, we don’t just analyze feminist AI, we actively construct it. 

Our mission is to forge technology that eradicates bias and elevates gender equity.

We work to ensure that the data machines ‘learn’ from reflects the world we want to live in. Because this data is used to create the algorithms that decide what matters, who will be hired, which resources will be allocated…

But today’s data is implicitly biased against women and marginalized groups. It defines yesterday, not tomorrow. That means the ‘rules’ we will live by for years to come are being written to reinforce the way things were.

To correct the bias, women and girls in all their diversity must be heard. We need a seat at the table. By connecting the right people, at the right place at the right time, women can and must be involved in all levels of policymaking.

Our activities include:

- **AI & EQUALITY:  A HUMAN RIGHTS TOOLBOX** — An online course and a community to equip technologists, decision makers and industry innovators with the tools and concepts to build a human rights-based approach to the core of the code 
- **A+ ALLIANCE for Inclusive Algorithms** — A global coalition of technologists, activists and academics championing feminist AI around the globe, Recognized as a World Changing Idea by Fast Company and spotlighted at the Paris Peace Forum
- **FA+IR NETWORK** — A consortium incubating innovation and networking change-makers to weave inclusion into the fabric of emerging technologies
- **G-APP: The Gender Gap** — Equips organizations with hard data to address diversity in conferences and events by measuring the difference between representation, participation, and influence
- **ADVOCACY for a Paradigm Shift** — Our message resonates from the halls of power to international forums, influencing discussions on trade, technology, democracy and inclusive policies.

Women@TheTable

Communicating the best research and data to understand big global problems and make progress against them

Poverty, disease, hunger, climate change, war, existential risks, and inequality: The world faces many great and terrifying problems. Our World in Data focuses on communicating the best research and data that helps us understand and find solutions to the world’s largest problems.


Our World in Data publishes an open-access publication where users can understand the state of the world today, where we are making progress and where we are falling behind. Through interactive data visualizations we can see how the world has changed; by summarizing the scientific literature we can understand why. We cover everything from global poverty to natural disasters, education and health, democracy; we have over 13,000 charts across hundreds of topics.


Our World in Data is free, open-source and provided as a public good. It has millions of users every month, and is cited in research and media across the world every day. This allows millions of people to understand the large problems the world is facing, and how we can solve them.

Our World in Data

MAPS works towards a post-prohibition world by advancing research, changing policies, and shaping culture. 

Since our founding in 1986, the Multidisciplinary Association for Psychedelic Studies (MAPS) has been the leading organization building the movement to foster evidence-based approaches to psychedelics and the people who use them. When used safely and responsibly, psychedelics have the potential to promote personal growth and well-being and treat various mental health conditions. Three pillars guide our efforts: advancing research, changing policies, and shaping culture. 

[Advancing Research](https://maps.org/advancing-research/)

MAPS spent decades developing MDMA-assisted therapy for the clinical utilization of psychedelic-assisted therapies. With the road paved for the next generation of research and drug development, MAPS now stewards the research landscape we helped cultivate.

We are dedicated to fostering new research directions that prioritize public benefit, supporting international researchers and pilot programs, and ensuring the accessibility and culturally appropriate integration of psychedelics as a tool for individual and community wellness. We center research that contributes to knowledge in the public domain.

[Changing Policy](https://maps.org/changing-policy/)

The cultivation, use, and trade of psychoactive substances — including psychedelics — has been a consistent aspect of human history, but prohibition, criminalization, and militarization — and their inherent oppression — have led to drastic consequences. The ongoing, global War on Drugs has been justified by bad science, racism, and fear for too long: it has led to mass incarceration; erosion of civil liberties; ecological damage; economic waste; and the public health polycrisis of adulteration, poisoning, and overdose. Many of these harmful effects have disproportionately impacted the most historically exploited and oppressed communities. Consequently, we believe societies worldwide have an obligation to account for and repair those harms, to the extent possible. 

MAPS envisions a post-prohibition future based on Consciousness, not Criminalization.

[Shaping Culture](https://maps.org/shaping-culture/)

For psychedelics to be most safely integrated into society, we need to be honest about the implications. MAPS recognizes the importance of a comprehensive understanding of their risks and potential benefits, teaching people how to navigate altered states of consciousness and how policies impact individuals and communities. 

We create cutting-edge education for professionals and the public, provide expert support for the psychedelic and drug policy movement, and convene people who share our vision—all to lay the groundwork and create the guardrails necessary for responsible social transformation. 

As psychedelics become more mainstream and an increasing number of people seek to use them for healing and personal growth, we are more dedicated than ever to making resources available for people and communities to safely and responsibly integrate psychedelics into medical, legal, and spiritual contexts.

MAPS

Terra Praxis designs and implements strategies that leverage science, technology and energy innovation for a prosperous planet

We co-founded TerraPraxis to design and implement strategies that leverage science, technology and energy innovation for a prosperous planet. Our mission is to innovate and accelerate scalable, equitable solutions for unsolved areas of the climate challenge. 

Our special focus is on enabling high-impact rapid transitions for neglected parts of the decarbonization challenge. 

We work with an extensive global network to define, incubate and initiate scalable strategies that fulfil the twin missions of prosperity and decarbonization. 

Terra Praxis

The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.

GiveWell

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