High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

Sentinel transforms pandemic prevention and response through cutting-edge technology, global collaboration, and local empowerment.

Infectious disease outbreaks have caused more illness, death, and economic loss than any other crisis in history. Pathogens kill millions of people each year and hit the most vulnerable communities the hardest. They go further—exposing and exploiting the deepest cracks in our societies and the risks are rising. 

 The forces driving pandemics are accelerating. Climate change is increasing human exposure to pathogens through animals and insects. Habitat encroachment and industrial agriculture are raising the risk of spillover. Global trade and travel speed disease spread, while conflict and instability weaken health systems. New biotechnologies pose engineered threats that current systems cannot detect. Over the past decade, the number of epidemics has grown by 20% worldwide. Between February and June 2025 alone, more than 70 outbreaks were reported across Africa. Yet global readiness is faltering. In the past year, U.S. investments in frontline health systems and disease surveillance have been sharply reduced. Funding cuts have disrupted networks and delayed the deployment of critical tools, especially in regions most vulnerable to outbreaks. Health programs across West and Central Africa now face rising threats with fewer resources and limited external support, leaving the world more exposed- with some experts estimating the probability of a pandemic in the next decade to exceed one in four.
 
Amid these mounting challenges, we stand at a historic moment of possibility. Sentinel, a pandemic early warning prevention and response program, is built to meet this moment: a locally led, technology-enabled model for proactive public health, integrating diagnostics, data, and training to stop outbreaks before they spread. 

Sentinel is an outbreak surveillance framework, designed to detect pathogenic threats in real-time and prepare the global community to stop diseases before they spread. It brings advanced science to the frontlines through a next-generation pandemic prevention system built around three core pillars. DETECT delivers rapid diagnostics and genomic surveillance. CONNECT integrates laboratory, clinical, and genomic data into real-time insights. EMPOWER invests in training, infrastructure, and institutional capacity so countries can lead their own outbreak responses.

DETECT: Timely diagnostics and sequencing are essential for early outbreak detection and effective response. Yet these capabilities remain limited in many LMICs, even for high-priority pathogens like Lassa, Ebola, and Marburg. Too often, health systems act only after outbreaks are widespread, costing precious time and lives. Sentinel’s DETECT pillar delivers speed, affordability, and accessibility through a tiered approach to diagnostic design and implementation.

CONNECT: Fragmented systems delay response and allow outbreaks to spread unchecked. When data are siloed, public health leaders lose time and visibility, undermining containment efforts. In contrast, integrated systems support faster, more effective action. Sentinel’s CONNECT pillar builds the digital backbone for outbreak response. Through interoperable dashboards and analytic platforms, it streamlines data flow, strengthens each stage of detection, analysis, and control, and enables real-time decision-making.

EMPOWER: Building local leadership and scientific capacity is central to Sentinel’s mission. Although over 60% of emerging infectious diseases originate in Africa and Asia, fewer than 10% of African countries had genomic surveillance at the start of COVID-19. Africa faces a shortfall of more than one million health workers, including critical gaps in genomics and data science. Sentinel’s EMPOWER pillar builds sustainable, locally led outbreak response by investing in people and communities. It enables local experts to detect and respond early with solutions grounded in context, shortening the path from innovation to public health practice and building resilient systems from within.

The foundation for Sentinel was laid over two decades through a 20-year partnership between Prof. Christian Happi, a Nigerian infectious disease expert, and Prof. Pardis Sabeti, a U.S.-based computational geneticist. Over the years this collaboration has established operational programs in Nigeria and Sierra Leone that connect health workers in rural clinics and hospitals with national and international public health leadership. **To date more than 3,000 public health workers from 53 of 54 countries in Africa** have been trained through Sentinel’s approach.

Sentinel-supported teams have enabled early detection and rapid response to Marburg, mpox, Lassa, dengue, and COVID-19, providing critical data to inform government action. 

COVID-19: Sentinel rapidly expanded genomic and diagnostic capacity across Africa, establishing pipelines with national partners. In March 2020, IGH sequenced Africa’s first SARS-CoV-2 genome within 72 hours of sample receipt. Sentinel supported testing for over 30 million people, deployed SHINE and CARMEN technologies, and led genomic surveillance in 26 countries. This work helped identify one of the first globally recognized variants of concern. Sentinel also trained scientists from 53 African countries, strengthening long-term preparedness. The Sentinel team also led one of the largest diagnostic and sequencing centers in the U.S. and supported global data sharing and informatics efforts.

Mpox: In 2023, Sentinel traced an mpox outbreak in Nigeria to oil workers in Rivers State, guiding the NCDC’s targeted vaccination strategy. Sentinel also hosted a three-week genomics bootcamp that trained regional professionals in real-time sequencing and analysis. Genomic data revealed sustained human transmission of the West African subtype, with signs of adaptation and rising pandemic potential. When an outbreak emerged in Sierra Leone in 2024, local public health teams, supported by Sentinel, initiated sequencing and shared real-time data. Analysis identified a new highly transmissible G.1 variant spreading beyond previously affected groups. Sentinel tools and team members remain central to guiding the national response.

 Marburg: In 2024, Sentinel supported the Rwandan government during a Marburg outbreak in Kigali. IGH provided outbreak reconstruction and real- time sequencing, while Prof. Happi co-chaired the national scientific response. The outbreak was contained at 66 cases, with the case fatality rate reduced to 22%, far below historical averages.

Building off of these successes, Sentinel is poised for its next phase: deepening national integration, expanding its reach, and advancing a globally transferable model for pandemic prevention. We will achieve full national implementation in Sierra Leone and move toward this in Nigeria, embedding surveillance into national systems and incorporating a One Health approach that addresses climate-linked and zoonotic threats. Expansion will continue to Senegal, Rwanda, and the Democratic Republic of Congo, where strong partners and readiness are in place. In parallel, we are globalizing Sentinel’s tools, data platforms, and training programs to create a lasting framework for pandemic prevention.

Sentinel will help millions benefit from earlier detection, faster response, stronger systems, and a globally connected early warning network. This is the moment to transform pandemic prevention and safeguard global health security for generations to come.

There will be another pandemic virus in our lifetimes—it may already be here, but our work is about more than stopping disease outbreaks. By empowering people and equipping them with the tools, the system, and the knowledge needed, we create strong and resilient communities for generations to come. Sentinel is about partnership, solidarity, and most importantly, hope!

That's why we believe that with you, we can make an impact.

Sentinel 

Not for profit, founded as a 501C3 charity in 2006 in NYC. Providing Health, Education, and Empowerment opportunities.

Our cornerstone project was building East & Central Africa's 1st Public Children's Hospital.  Since opening in 2015, we have treated over 1.3 million kids. The impact does not end there, we have also constructed six public (free-to-attend) schools, a dairy project, a kids community house and more. We also run a vibrant Women's Empowerment Project focusing on agri-biz and domestic violence survivors.  Our latest major project is constructing the first children's cancer hospital in sub-Saharan Africa.

visit our Learn About Us page on shoe4africa.org

Shoe4Africa

We provide cash incentives for childhood vaccinations. It’s one of the most cost-effective ways known to save lives.


New Incentives’ mission is to save lives in a way that does the **most good per dollar**.
Guided by evidence, we provide cash incentives to increase childhood vaccination rates.

- We [raise awareness](https://www.newincentives.org/blog-posts/awareness-activities) about the benefits of childhood vaccinations.
- We [provide cash incentives](https://www.newincentives.org/blog-posts/a-day-in-the-life-abubakar-aliyu-field-officer) at government clinics after children receive vaccinations.
- We [help improve the vaccine supply chain](https://www.newincentives.org/blog-posts/supporting-government-partners-with-vaccine-supply-efforts) to ensure enough vaccines are available at clinics.

Together, these efforts are proven to double vaccination rates and save lives.
Learn more about the [randomized controlled trial](https://www.newincentives.org/rct-results).

As of March 2024, New Incentives has reached more the 3 million infants in northern Nigeria.

New Incentives

LifeStraw operates the Safe Water Fund, a 501(c)3 project, to support the provision of safe water where it is needed most.  

The Safe Water Fund operates as a 501(c)(3) project, supporting the implementation of long-term, sustainable safe water programs worldwide. We partner with grassroots organizations and local leaders to identify and reach communities and families most in need.

In addition to our retail-funded Give-Back program, the Safe Water Fund provides safe water during humanitarian emergencies and natural disasters. We also lead special initiatives in the cities where our employees live, including at our headquarters in Baltimore City, and participate in Giving Tuesday efforts each year.

**100% of donated funds go directly toward products and the distribution of safe water supplies. Vestergaard Frandsen, Inc. (d/b/a “LifeStraw”) does not profit from your donation.**

*The Safe Water Fund operates through a fiscal sponsorship with Players Philanthropy Fund, a Texas nonprofit recognized by the IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178, ppf.org/pp). Contributions to the Safe Water Fund qualify as tax-deductible.*

Your contribution helps us bring safe drinking water to more families. 

Thank you for your support!

LifeStraw Safe Water Fund

Phare Bio is using AI/deep learning to discover novel classes of antibiotics to address a looming crisis in antibiotic resistance.

Phare Bio is an ambitious social venture using novel AI and deep learning approaches to antimicrobial development in collaboration with Professor Jim Collins at MIT, a founder of the field of synthetic biology. Phare is a recipient of the Audacious Project, a collaborative funding initiative between TED and other non-profits to unlock social impact on a grand scale. 

The rapid evolution of antibiotic-resistant bacteria and a dwindling discovery pipeline have resulted in an antimicrobial resistance (AMR) crisis. Today, according to the Centers for Disease Control and Prevention, someone in the U.S. acquires a resistant infection every 11 seconds; every 15 minutes someone dies as a result of one. Covid-19 has only highlighted the urgency with approximately 15% of hospitalized patients suffering from bacterial co-infections. There is a critical need for new antibiotics, and yet, pharmaceutical and biotechnology companies have largely abandoned the space in favor of more lucrative markets. 

Phare Bio launched in 2020 to tackle this critical unmet need with the latest advances in machine learning to develop entirely novel antibiotics. Integrating world-class expertise and decades of experience in artificial intelligence (AI), bioengineering, and life sciences, Phare is targeting the world's most deadly pathogens, such as Acinetobacter and Pseudomonas, with the goal of developing seven novel classes of antibiotics in seven years. 

Phare Bio

Delivering medical aid where it's needed most — independent, neutral, impartial.

Doctors Without Borders/Médecins Sans Frontières (MSF) is an international medical humanitarian organization created by doctors and journalists in France in 1971.

In over 70 countries around the world, MSF saves lives by providing medical aid where it is needed most—in armed conflicts, epidemics, natural disasters, and other crises.  The people who work for MSF are doctors, nurses, midwives, epidemiologists, water-and-sanitation experts and many others who combine their professional expertise with a commitment to the world’s most vulnerable people.  Each year, these medical teams run close to 470 projects where they care for millions of people.  

As an organization, MSF is neutral and operates independently of any political, military, or religious agendas. It does not take sides in armed conflicts, provides care based on needs alone, and advocates for increased independent access to victims of conflict and disaster as required under international humanitarian law. Medical teams conduct evaluations on the ground to determine a population's medical needs before opening programs, aiming to fill gaps that exist (rather than replicating services that are already offered) or reach communities that are not being assisted.  Over the years, the organization has been the recipient of several awards that recognize its work, including the 1998 Conrad N. Hilton Humanitarian Prize, the 1999 Nobel Peace Prize, the 2012 J. William Fulbright Prize for International Understanding, the 2015 Lasker-Bloomberg Public Service Award, and the 2017 Pardes Humanitarian Prize for Mental Health.

Doctors Without Borders/Médecins Sans Frontières (MSF) 

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I believe in gratitude+action and that together we can build a better world. Cofounder at Every.org :)

founder @ camp.org, expa.com, uber.com & mix.com

.css-1wjgqn{display:inline-block;--textSize:1.5rem;--lineHeight:1.7999999999999998rem;line-height:var(--lineHeight);font-size:var(--textSize);width:100%;}Disease Prevention

Mersal Foundation for Charity and Development

Mersal Foundation for Charity and Development

The Against Malaria Foundation

Mersal Foundation for Charity and Development

Mersal Foundation for Charity and Development

Mersal Foundation for Charity and Development

Disease Prevention