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Excellent work and remarkable transparency for a nonprofit

ConnectMyVariants work in the community saves lives! 

People in poverty deserve access to high quality dental care-- and Community Dental Care provides that in a culturally sensitive manner to people of all ages and abilities!

We target opportunities where small investments can generate extraordinary impact and create lasting change.

There are many charities that address global poverty and suffering. 

With our Global Health & Development (GHD) **Catalytic Impact Fund**, we try to find the strategic pressure points where modest funding unlocks transformational change. 

By prioritizing these leverage points, we help donors maximize their impact in building sustainable, long-term solutions to global poverty and suffering — saving and improving as many lives as possible with each dollar.

What does catalytic impact look like?

- **We trigger systemic improvements**: We support investments that create new long-term infrastructure or increase the cost-effectiveness of existing systems.
- **We remove key bottlenecks**: We identify and remove barriers that stand in the way of accelerated impact.
- **We crowd in capital**: We provide early-stage funding that attracts substantial follow-on investment for cost-effective opportunities.

### Our Approach to Grantmaking

When evaluating potential grants, we consider several key points:

- **Counterfactual impact**. Our grants are designed to create meaningful outcomes that would not otherwise have happened. This means that you can rely on the Funds to create meaningful, real change, rather than just maintaining the status quo.
- **Impact-driven philanthropy**. This fund prioritizes the highest-impact solutions to challenges. We assess where the gaps are, which opportunities may be neglected by other funders, and where the biggest wins are in terms of making the biggest difference.
-  **The organization’s funding gap**. Not all organizations are set up to scale programs and some may not be able to productively absorb large amounts of unsolicited funding at any given point. We evaluate all potential grantees’ capacity for growth and consider how much money they could put to good use.
-  **Organizational strength**. Particularly with unrestricted funding, it’s important to have trust in the leadership and capacity of the organizations we support. We look at their track record of success and their transparency about failures as well as successes, and we only support those organizations which are exceptionally well run.
- **Time-critical opportunities and funding certainty**. Sometimes there are time-critical opportunities which require fast decisions. We will use the Fund to make grants that enable such short-term opportunities and stability for high-impact funding opportunities thereby increasing the impact compared to individual giving to specific organizations.

### Frequently-Asked Questions

**Can charities apply for money from the Fund?**

Founders Pledge reviews [requests for funding](https://www.founderspledge.com/requests-for-funding) from organizations, but does not guarantee we can fill funding requests.

**How frequently will you make grants from the Fund?**

In general, Fund Managers will review grantmaking decisions on a quarterly basis, based on the value of Funds and the available options for high-impact grantmaking. We may disburse funds outside of quarterly review dates if we become aware of a particularly promising and time-sensitive funding.

**How will my contribution be used?**

All funds are granted out — every dollar contributed to the Fund will be used to make grants directly to end-user organizations creating a real difference.

### More Questions?

To learn more about the Founders Pledge GHD Catalytic Impact Fund, please visit [founderspledge.com](https://founderspledge.com/funds/global-health-and-development-fund) or email the team at [funds@founderspledge.com](mailto:funds@founderspledge.com).

Founders Pledge: GHD Catalytic Impact Fund

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

Delivering medical aid where it's needed most — independent, neutral, impartial.

Doctors Without Borders/Médecins Sans Frontières (MSF) is an international medical humanitarian organization created by doctors and journalists in France in 1971.

In over 70 countries around the world, MSF saves lives by providing medical aid where it is needed most—in armed conflicts, epidemics, natural disasters, and other crises.  The people who work for MSF are doctors, nurses, midwives, epidemiologists, water-and-sanitation experts and many others who combine their professional expertise with a commitment to the world’s most vulnerable people.  Each year, these medical teams run close to 470 projects where they care for millions of people.  

As an organization, MSF is neutral and operates independently of any political, military, or religious agendas. It does not take sides in armed conflicts, provides care based on needs alone, and advocates for increased independent access to victims of conflict and disaster as required under international humanitarian law. Medical teams conduct evaluations on the ground to determine a population's medical needs before opening programs, aiming to fill gaps that exist (rather than replicating services that are already offered) or reach communities that are not being assisted.  Over the years, the organization has been the recipient of several awards that recognize its work, including the 1998 Conrad N. Hilton Humanitarian Prize, the 1999 Nobel Peace Prize, the 2012 J. William Fulbright Prize for International Understanding, the 2015 Lasker-Bloomberg Public Service Award, and the 2017 Pardes Humanitarian Prize for Mental Health.

Doctors Without Borders/Médecins Sans Frontières (MSF) 

ConnectMyVariant's mission is to end hereditary disease by bringing families together.

ConnectMyVariant is an educational health-focused 501(c)3 nonprofit organization that supports individuals and families with hereditary disease in their early detection and prevention efforts. We provide unique value by leveraging our evidenced-based family connection protocols to help people identify other at-risk relatives and help those relatives access genetic testing so that they can get optimal medical care. ConnectMyVariant brings people with the same genetic risk together through our variant database and community engagement events to share experiences and find common ancestors. ConnectMyVariant also works to increase awareness of the benefits of family outreach among physicians, others who provide prevention care, and the broader genealogy community.
 
Our key activities are:

- Working with patients to implement personalized family outreach plans
- Interactive educational workshops about sharing information on inherited disease risk
- Variant specific family reunions to share stories and plan outreach to cousins
- Genealogy assistance to help connect individuals in variant groups
- Individual equity and inclusion grants for family and community outreach

Need and Impact:
When hereditary disease risk is known, family outreach has been proven to be the most effective and cost-effective intervention for early detection and prevention. This family outreach, also known as cascade testing, is recommended by multiple guidelines. Despite overwhelming evidence, family outreach assistance is not reimbursed by insurance or integrated into healthcare. Many people suffer and die from hereditary disease that could have been prevented or caught early.
 
We have shown that our strategies to encourage family outreach can act as a communication multiplier. Our pilot research at the University of Washington showed that this approach enhanced patient experience, was considered ethical, and was appreciated by newly identified relatives. Our approach is low-cost and is 25 to 50 times more effective than awareness and education interventions that target the general population.

Equity and Inclusion:
ConnectMyVariant is committed to being a leader for equity, diversity, and inclusion in hereditary disease prevention. ConnectMyVariant’s goal is to spread awareness among all individuals and families about inherited disease risk. All project staff, participants, and partners in ConnectMyVariant have an equal voice in developing innovative ways to improve hereditary disease outreach and prevention for all people. By fostering a diverse and inclusive community, we can provide knowledge and opportunities that have been historically inaccessible to millions of people.

ConnectMyVariant

We provide comprehensive oral health care for people in need of all ages. Serving 50,000 patients annually at 5 clinics in MN. 

Our mission is to provide culturally sensitive community oral health care, preventive education, professional training, and to advocate for access for all. 

Our vision is that all people will have access to high quality, affordable dental care to improve their overall health in a convenient, caring, and respectful environment.

We are a nonprofit organization, and we serve patients from all walks of life and economic circumstances. We want to make high-quality dentistry available to anyone who needs care. We have over 200 dedicated employees, including dentists, hygienists, assistants, and an administrative team who are continually improving care and delivering the best possible dentistry.

Community Dental Care

We provide cash incentives for childhood vaccinations. It’s one of the most cost-effective ways known to save lives.


New Incentives’ mission is to save lives in a way that does the **most good per dollar**.
Guided by evidence, we provide cash incentives to increase childhood vaccination rates.

- We [raise awareness](https://www.newincentives.org/blog-posts/awareness-activities) about the benefits of childhood vaccinations.
- We [provide cash incentives](https://www.newincentives.org/blog-posts/a-day-in-the-life-abubakar-aliyu-field-officer) at government clinics after children receive vaccinations.
- We [help improve the vaccine supply chain](https://www.newincentives.org/blog-posts/supporting-government-partners-with-vaccine-supply-efforts) to ensure enough vaccines are available at clinics.

Together, these efforts are proven to double vaccination rates and save lives.
Learn more about the [randomized controlled trial](https://www.newincentives.org/rct-results).

As of March 2024, New Incentives has reached more the 3 million infants in northern Nigeria.

New Incentives

CHILA seeks to provide quality healthcare to our Q’eqchi communities while respecting their cultural practices and traditions.

What are you supporting when you support CHILA’s mission?

When you support CHILA’s mission, you are saving lives
When you support CHILA’s mission, you are alleviating suffering
When you support CHILA’s mission, you are making magic happen…

There is a magic in seeing someone smile because they finally found someone who is listening.  There is magic in the relief that is felt when you help someone feel better.  There is magic when you connect and engage and show someone that you understand.

CHILA is a non-profit health clinic in Chisec Guatemala and all of our services are offered free of charge to anyone who walks into our clinic.  We rely on supporters like you to help us provide the highest quality of care for the residents of Chisec and her surrounding regions and connect our patients to living healthier lives.

Your gift provides:
~Highest quality of primary medical care
~Medication and treatment for acute and chronic medical conditions such as diabetes and high blood pressure, etc.
~Diagnostic Tests such as blood tests, ultrasound, radiological exams, biopsies etc.
~Specialty Consults such as orthopedic, pediatric, oncology, surgical etc.
~Transportation to hospital and clinic visits in Coban (2 hours), Guatemala City (6-8 hours) and other locations
~Translator services in their Q'eqchi language
~Monthly Diabetes Clinic

And so much more….

Your support does more than just provide medical services for the community.  Through educational opportunities, healthcare professionals and ancillary personnel are trained by CHILA to continue to provide care to their community in conjunction with telemedicine support with Dr. Smith.  By growing opportunities for the the local community, your support helps to strengthen their healthcare structure from within and helps to encourage local independence.

Access to healthcare is so much more than an open clinic door.  It is access to clean water, access to education, women’s rights and gender equity, food security, addressing domestic violence, access to functioning roads, transportation systems.  The health of a person is reliant on so many factors that are happening in a culture and in a community.  Your support is helping CHILA address the many issues that continue to affect health outcomes and access to healthcare in the Chisec community.

COVID-19 response:

In March of 2020, CHILA just completed what would be, unknowingly,  the last annual dental and medical mission with Kindness in Action due to the pandemic.  2 weeks later, the COVID-19 pandemic was declared and the border was closed and just like that, our in-person clinics ceased operations for over a year.   Like all the countries in the world, COVID-19 hit the communities of poor and disenfranchised the hardest.  But the CHILA team of Chisec rised to the occasion.  The team immediately gathered all the reliable scientific information that was being presented and they were one of the first to organize educational videos on virus information and prevention, proper hand washing techniques, and self-care and mental health awareness during quarantine all in the Q’eqchi Maya language.  They organized seamstresses to mass produce masks for the community with proper distancing and mask wearing observed.  They put together and delivered PPE packs to the staff of the local Centro de Salud and delivered food parcels to those communities that were having hardships with food security.  Here is what your support is provided:

~Oxygen concentrator machines
~Oxygen delivery supplies such as masks, nasal cannulas, nebulizers
~Medications packs with Tylenol, steroids, cough medicine etc.
~Vaccination education and outreach with the local healthcare system
~PPE and disinfectant supplies



CHILA’s Mission:

~Provide high-quality primary care for the populations of rural Guatemala
~Strengthen and work with the existing community healthcare system
~Preserve Q'eqchi Maya traditions and incorporate traditional Maya herbal medicine as part of our treatment modality
~Strengthen the activities of the local Women's Groups as partners in healthcare access
~Provide all healthcare in the native Q’eqchi Maya language
~Deliver excellence in healthcare no matter the ability to pay

Our History and Our Present:

CHILA was started by Brian Smith, MD in the town of Chisec, Guatemala.  Brian served as a member of the Peace Corps in the region and witnessed firsthand the lack of access to healthcare for the population in the area.  Once he returned to the United States, he changed his vocation from engineering to medicine.  He entered medical school and became a physician while concurrently traveling back and forth to Chisec to build and open a medical clinic.  CHILA has grown with the belief that no person should die or be denied healthcare because of where you were born.  After years of providing care to many people in the region, CHILA was recognized as a nonprofit organization in 2019.

Currently, CHILA funds a small group of local medical professionals in Chisec who we pay to provide ongoing  and prescribed care for chronic and complex medical conditions.  Dr. Smith and a contingency of volunteer medical providers from the United States travels to Chisec several times a year to hold clinics in our Chisec location as well as a variety of villages in the region.  During these clinic days, we see cases of varying levels of complexity.  We are able to treat common ailments during these clinic days as well as establish longer term care plans for more complex and chronic issues.  We provide all these services with translators who can speak in the native Q’eqchi language.

Chila Inc

LifeStraw operates the Safe Water Fund, a 501(c)3 project, to support the provision of safe water where it is needed most.  

The Safe Water Fund operates as a 501(c)(3) project, supporting the implementation of long-term, sustainable safe water programs worldwide. We partner with grassroots organizations and local leaders to identify and reach communities and families most in need.

In addition to our retail-funded Give-Back program, the Safe Water Fund provides safe water during humanitarian emergencies and natural disasters. We also lead special initiatives in the cities where our employees live, including at our headquarters in Baltimore City, and participate in Giving Tuesday efforts each year.

**100% of donated funds go directly toward products and the distribution of safe water supplies. Vestergaard Frandsen, Inc. (d/b/a “LifeStraw”) does not profit from your donation.**

*The Safe Water Fund operates through a fiscal sponsorship with Players Philanthropy Fund, a Texas nonprofit recognized by the IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178, ppf.org/pp). Contributions to the Safe Water Fund qualify as tax-deductible.*

Your contribution helps us bring safe drinking water to more families. 

Thank you for your support!

LifeStraw Safe Water Fund

Our mission is to protect LGBTQ+ youth in Poland from the harms of homelessness and refugeehood. 

The Warsaw House Foundation's mission is to protect homeless and refugee  LGBTQ+ youth in Poland and provide them with the tools they need to live independently. Our inspiration was the  Ali Forney Center  (AFC)  n NYC, which is largest organization in the world offering support to homeless LGBTQ+ youth. We are honored that Carl Siciliano, the AFC's founder is on the board of the Warsaw House Foundation and works as an advisor. We place extra attention on HIV and STI education, support and prevention with the help of board member Dr. Joanna Kubica and the Smart Life Clinic in Warsaw.  After we took in our first LGBTQ+ youth to house on February 14th, 2023  we have been flooded with calls for housing and support from young people in need.  These are Polish Trans 18 year-olds from the Polish countryside in desperate need to escape their abusive and intolerant homes, young queer people with PTSD and untreated mental illness who need housing and support immediately, LGBTQ+ refugees from Ukraine and several young gay men from Iraq who suffered torture in their homeland, were detained and imprisoned at the Polish/Belarussian border for up to two years, and are now trying to build their lives in Poland.  We are also housing and supporting young LGBTQ+ people from Uganda and Egypt,  We are raising money to support the young people under our care, to house and feed them and pay for their medical needs and courses needed for them to start an independent life,  We are also raising money to hire staff (all of WH's work is now done by volunteers), to continue the renovation of our residential building and for short term emergency rentals.  We have a committed and professional team and a well planned strategy for both emergency and long term care.  Any help would be greatly appreciated!! We will be in regular contact if you'd like to hear of our progress and  if you'll be in Warsaw, we'd be delighted to meet with you personally and show you the work we do.

Warsaw House Foundation

Odylia Therapeutics is a nonprofit biotech working to accelerate the development of treatments for people with rare diseases.

At Odylia, we accelerate therapeutic development for people with rare diseases, changing the way treatments are brought from the lab to the clinic. We strive to bring life altering treatments to people with genetic disease regardless of prevalence or commercial interest. 
Odylia is shifting the paradigm to focus on proven science and removing traditional roadblocks. We work to lower costs, reduce development time, focus research, and continuously drive successful programs towards clinical trials and regulatory approval. Strategic collaborations with patient groups, research labs, and commercial partners facilitate our work to ensure treatments are safe, effective, and ultimately reach patients who need them.

Odylia challenges the traditional approach to drug development through:

1. Lower cost of development
Lower licensing fees to decrease development costs and ensure continued commitment to program success

2. Increase speed of development
Challenge traditional approaches through regulatory engagement

Streamline development through strategic partnerships and a platform approach to drug development

3. Enable the entire ecosystem
Provide expertise through in-house Brydge Solutions and leveraging the Odylia Board

Enable the entire ecosystem through Initiatives that impact the broader field

Odylia Therapeutics

An organization focused on diseases, disorders, and medical disciplines. It received its nonprofit status in 2022.

Preventable and curable diseases persist in neglected populations because quality medicines fail to reach those in need. Though treatments exist, low supply, poor packaging, and counterfeit drugs reduce trust and coverage in low- and middle-income countries.

We address this by producing essential medicines in short supply and improved medicines for mass drug administration. Our drugs are reliable, high-quality, and packaged in child-resistant, tamper-evident, and eco-friendly materials that are easy to understand.

**At Bend Biomedical, we believe everyone deserves quality medicine. Period.**

Bend Biomedical

Prevention, control and treatment of malaria and other communicable diseases among vulnerable populations.

Malaria Consortium US, Inc. (MC-US) is a registered 501(c)(3) public charity and shares the mission of Malaria Consortium, a globally recognized organization committed to reducing deaths and illnesses caused by malaria and other preventable and treatable diseases across Africa and Asia.

Our mission is to save lives and improve health in Africa and Asia through evidence-based programs that tackle malaria and other priority diseases while advancing universal health coverage (UHC). In the US, we build partnerships with foundations, donors, and philanthropic organizations to ensure that every contribution makes a lasting impact for those most in need.

As a leader in malaria control and elimination, our work focuses on interventions such as seasonal malaria chemoprevention (SMC), malaria vaccines, disease surveillance, and integrated child health services. We work in collaboration with governments, communities, and health systems to improve access to essential healthcare and strengthen delivery of services in underserved and hard-to-reach areas.

As a leader in interventions such as chemoprevention and vector control, we rely on evidence and our expertise to deliver established interventions, influence other effective interventions and guide new strategies to reduce the burden of malaria, pneumonia, dengue, malnutrition and diarrhea. We work with communities and all levels of the health system to improve access to and demand for primary healthcare services and overall quality of care.

Our tailored interventions seek to improve equity by providing quality, affordable health services to marginalized populations (particularly women and girls and those living in hard-to-reach areas). To ensure barriers to achieving UHC are addressed and to encourage sustainability, we work closely with governments to integrate our programs within existing health systems and structures in the countries in which we work.

We promote disease surveillance as a core intervention to engage communities to improve the quality and accessibility of routine health information by using digital tools and approaches that strengthen the linkages between case-level data and national health information systems. We combine capacity development at community level with the use of innovative tools and platforms to enhance local capabilities to interpret and use these data most effectively.

All of our work is informed by our core values: accountability, integrity, dignity and equity.

Malaria Consortium

One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

Founders Pledge is a global nonprofit empowering entrepreneurs to do the most good possible with their charitable giving. 

Maximize your philanthropic impact with Founders Pledge. We empower a global community of over 2,100 members, equipping them with everything needed to give effectively: from evidence-led research and expert advice on the world's most pressing problems to comprehensive infrastructure for seamless global grant-making, and a powerful network for collaboration. Together, we've already channeled over $1.5 billion to high-impact causes globally, tackling critical issues like climate change, global health, and emerging existential risks. 

When you donate through every.org today, you're joining this proven movement, and our unique funding model ensures 100% of your contribution goes directly to charity, as our operational costs are generously covered by a dedicated community of philanthropists.

Donate this Giving Season and we'll match your donation up to a value of $750,000, until Dec 31.

Founders Pledge

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We are a nonprofit, so we rely on the generosity of donors like you.

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Founders Pledge: GHD Catalytic Impact Fund

Mersal Foundation for Charity and Development

Mersal Foundation for Charity and Development

Doctors Without Borders/Médecins Sans Frontières (MSF)

Mersal Foundation for Charity and Development

ConnectMyVariant

Disease Prevention