Absolutely fantastic work Oli & Rowan, this will help so many people. Keep up the great work, we hope this helps! 

In memory of Clark Fenton, a good man gone too soon.

I’m praying you can find a gene cure for Anders Payne’s eyes! One of my beloved grandsons. ❤️❤️❤️

Micronutrient malnutrition is the leading cause of preventable intellectual and developmental disabilities in the world.

Delivering mobile-based rehabilitation programs to treat COPD, making treatment accessible in areas where it is currently lacking.

**Overview**
Respira Health is developing a free, mobile-based pulmonary rehabilitation program to close the treatment gap for chronic obstructive pulmonary disease (COPD) - India’s second leading cause of death. Incubated in March 2025 through Ambitious Impact’s Charity Entrepreneurship Program, we are in the early stages of building a scalable, cost-effective model for delivery across low-resource settings.

**The Problem**
COPD is the fourth leading cause of death globally, responsible for over 3 million deaths annually. Critically, 90% of these deaths occur in low- and middle-income countries (LMICs), where limited healthcare capacity and logistical challenges prevent patients from accessing effective treatment. In India, this treatment gap is especially pronounced, despite the availability of proven interventions.

**Our Solution**
Pulmonary rehabilitation (PR) is a well-established intervention combining strength and cardio exercises, breathing techniques, lifestyle support (e.g., smoking cessation), and psychological care. Research shows that just three PR sessions can reduce the risk of death by 9%. Digital delivery of PR via mobile phones or web platforms has been shown to be as effective as in-person programs, but at a fraction of the cost. Respira Health is adapting existing PR content into a mobile-first format accessible via widely used platforms like WhatsApp to ensure it reaches underserved COPD patients across India.

**Current Activities**
We are conducting scoping visits in Mumbai and Delhi from July - September 2025. Our objectives are to:

- Understand the burden of COPD and the broader healthcare landscape.
- Conduct needs assessments with healthcare workers and patients.
- Test key assumptions around digital platform usability, referral pathways, and patient adherence.
- Build relationships with potential collaborators for future pilot implementation.

**Future Plans**
Upon completion of our proof-of-concept phase, we will fundraise for a pilot launch. Our primary goal for Year 1 is to demonstrate uptake, engagement, and adherence in low-resource communities, paving the way for scale-up in 2026.

**Impact Potential**
Our intervention could provide millions of COPD patients with access to life-extending care currently out of reach. By leveraging digital tools, we aim to overcome traditional delivery barriers and radically expand access to pulmonary rehabilitation. We estimate that the average patient completing our program will gain over six months of healthy life. Based on our cost modelling, we anticipate averting a disability-adjusted life year (DALY) for just $20 - making our intervention potentially five times more cost-effective than GiveWell’s funding bar for highly cost-effective charities.

Respira Health

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

The Rapid Response Fund will fill critical time-sensitive funding gaps created by the suspension of US foreign aid.

The U.S. government's cuts to foreign aid have created an urgent crisis — high-impact, evidence-based programs in global health, extreme poverty, and humanitarian aid are suddenly at risk. Organizations delivering lifesaving interventions now face unexpected shortfalls that could cost lives. We can’t afford to let that happen.

Times of crisis require swift and decisive action. That’s why **The Life You Can Save** and **Founders Pledge** have jointly launched the Rapid Response Fund — a fast, strategic way to bridge gaps in funding and keep the most effective programs running at full capacity open for donations from all who care about the impact of this crisis.

We’re collaborating with experts and former USAID leaders at **Project Resource Optimization** (PRO) to identify and support the most cost-effective interventions in global health & development. Our recommended partners are among the best in the world at turning dollars into impact, but they now face an unprecedented funding crunch.

This fund will provide urgent bridge support and sustain essential services for our current recommended funding opportunities while also allowing us the agility to seize new high-impact opportunities as they arise in this rapidly shifting landscape. Every dollar you donate goes where it’s needed most — help us act now before it’s too late.

Founders Pledge & The Life You Can Save: Rapid Response Fund

Odylia Therapeutics is a nonprofit biotech working to accelerate the development of treatments for people with rare diseases.

At Odylia, we accelerate therapeutic development for people with rare diseases, changing the way treatments are brought from the lab to the clinic. We strive to bring life altering treatments to people with genetic disease regardless of prevalence or commercial interest. 
Odylia is shifting the paradigm to focus on proven science and removing traditional roadblocks. We work to lower costs, reduce development time, focus research, and continuously drive successful programs towards clinical trials and regulatory approval. Strategic collaborations with patient groups, research labs, and commercial partners facilitate our work to ensure treatments are safe, effective, and ultimately reach patients who need them.

Odylia challenges the traditional approach to drug development through:

1. Lower cost of development
Lower licensing fees to decrease development costs and ensure continued commitment to program success

2. Increase speed of development
Challenge traditional approaches through regulatory engagement

Streamline development through strategic partnerships and a platform approach to drug development

3. Enable the entire ecosystem
Provide expertise through in-house Brydge Solutions and leveraging the Odylia Board

Enable the entire ecosystem through Initiatives that impact the broader field

Odylia Therapeutics

We give small mills everything they need to add vital nutrients into the food that millions of malnourished people eat the most.

Sanku combats hidden hunger and saves lives by giving small mills the tools needed to fortify maize flour, an East African staple. Our mission: Guarantee that every meal consumed by every mother & child contains vital nutrients, forever. 

Worldwide, 8,000 children die every day and 2 billion suffer from preventable illness because their diets lack basic vitamins and minerals. Fortification (adding life-saving micronutrients to processed foods) is the most cost-effective nutrition intervention, but it has failed to reach the 6.5 billion people in developing countries who rely on small, often rural, mills for most of their food.

Sanku developed a technology and business model to enable the small mills that feed the most malnourished people to conveniently and affordably fortify staple grains. Our technology adds precise levels of nutrients into flour during processing and our business model leverages economies of scale to offset any additional costs for millers and their customers, providing Sanku with revenue margins that increase as we scale. We are currently reaching 3 million East Africans with the basic human right of nutritious food and have a plan to reach 100 million this decade, which will prevent millions from death and disease, boost productivity, and save billions of dollars in GDP.  

A donation of ~$1 is enough to give one person access to nutritious food for an entire year, so even a small donation can go a long way in the fight against malnutrition.

Sanku

Prevention, control and treatment of malaria and other communicable diseases among vulnerable populations.

Malaria Consortium US, Inc. (MC-US) is a registered 501(c)(3) public charity and shares the mission of Malaria Consortium, a globally recognized organization committed to reducing deaths and illnesses caused by malaria and other preventable and treatable diseases across Africa and Asia.

Our mission is to save lives and improve health in Africa and Asia through evidence-based programs that tackle malaria and other priority diseases while advancing universal health coverage (UHC). In the US, we build partnerships with foundations, donors, and philanthropic organizations to ensure that every contribution makes a lasting impact for those most in need.

As a leader in malaria control and elimination, our work focuses on interventions such as seasonal malaria chemoprevention (SMC), malaria vaccines, disease surveillance, and integrated child health services. We work in collaboration with governments, communities, and health systems to improve access to essential healthcare and strengthen delivery of services in underserved and hard-to-reach areas.

As a leader in interventions such as chemoprevention and vector control, we rely on evidence and our expertise to deliver established interventions, influence other effective interventions and guide new strategies to reduce the burden of malaria, pneumonia, dengue, malnutrition and diarrhea. We work with communities and all levels of the health system to improve access to and demand for primary healthcare services and overall quality of care.

Our tailored interventions seek to improve equity by providing quality, affordable health services to marginalized populations (particularly women and girls and those living in hard-to-reach areas). To ensure barriers to achieving UHC are addressed and to encourage sustainability, we work closely with governments to integrate our programs within existing health systems and structures in the countries in which we work.

We promote disease surveillance as a core intervention to engage communities to improve the quality and accessibility of routine health information by using digital tools and approaches that strengthen the linkages between case-level data and national health information systems. We combine capacity development at community level with the use of innovative tools and platforms to enhance local capabilities to interpret and use these data most effectively.

All of our work is informed by our core values: accountability, integrity, dignity and equity.

Malaria Consortium

We provide cash incentives for childhood vaccinations. It’s one of the most cost-effective ways known to save lives.


New Incentives’ mission is to save lives in a way that does the **most good per dollar**.
Guided by evidence, we provide cash incentives to increase childhood vaccination rates.

- We [raise awareness](https://www.newincentives.org/blog-posts/awareness-activities) about the benefits of childhood vaccinations.
- We [provide cash incentives](https://www.newincentives.org/blog-posts/a-day-in-the-life-abubakar-aliyu-field-officer) at government clinics after children receive vaccinations.
- We [help improve the vaccine supply chain](https://www.newincentives.org/blog-posts/supporting-government-partners-with-vaccine-supply-efforts) to ensure enough vaccines are available at clinics.

Together, these efforts are proven to double vaccination rates and save lives.
Learn more about the [randomized controlled trial](https://www.newincentives.org/rct-results).

As of March 2024, New Incentives has reached more the 3 million infants in northern Nigeria.

New Incentives

Founded In 1977, BeatCancer.Org offers holistic cancer education for patients, family members, caregivers & medical professionals.

BeatCancer.org (The Center for Advancement in Cancer Education) is a 48-year-old nonprofit dedicated to impacting lives through holistic, evidence-informed cancer education and support. Our mission is to empower individuals to prevent, deal with, and overcome cancer using dietary, lifestyle, and other non-toxic approaches that support the whole person—body, mind, and spirit.

We provide free one-on-one counseling to cancer patients through our in-house Naturopathic Doctor. This program ensures that anyone, regardless of financial status, can receive personalized, compassionate guidance on their healing journey.

We also offer a comprehensive online certification program that trains holistic cancer coaches, equipping patients, caregivers, and health professionals with the knowledge and tools they need to make informed choices. Our graduates go on to support others in their communities and practices, creating a ripple effect of healing and awareness.

We also offer continued support to our certified coaches through mentorship, community access, business development resources, and promotional efforts, helping them grow their impact and reach more people.

Your donation directly supports our ability to offer free cancer counseling, expand our educational outreach, maintain up-to-date resources, and fund scholarships for those in need. Every dollar helps us reach more people with life-changing information and reduce unnecessary suffering caused by cancer.

We are a small, mission-driven team with a long track record of results, heart-centered leadership, and a global reach. Join us in changing lives through education, one person at a time.

Center For Advancement In Cancer Education (BeatCancer.Org)

LifeStraw operates the Safe Water Fund, a 501(c)3 project, to support the provision of safe water where it is needed most.  

The Safe Water Fund operates as a 501(c)(3) project, supporting the implementation of long-term, sustainable safe water programs worldwide. We partner with grassroots organizations and local leaders to identify and reach communities and families most in need.

In addition to our retail-funded Give-Back program, the Safe Water Fund provides safe water during humanitarian emergencies and natural disasters. We also lead special initiatives in the cities where our employees live, including at our headquarters in Baltimore City, and participate in Giving Tuesday efforts each year.

**100% of donated funds go directly toward products and the distribution of safe water supplies. Vestergaard Frandsen, Inc. (d/b/a “LifeStraw”) does not profit from your donation.**

*The Safe Water Fund operates through a fiscal sponsorship with Players Philanthropy Fund, a Texas nonprofit recognized by the IRS as a tax-exempt public charity under Section 501(c)(3) of the Internal Revenue Code (Federal Tax ID: 27-6601178, ppf.org/pp). Contributions to the Safe Water Fund qualify as tax-deductible.*

Your contribution helps us bring safe drinking water to more families. 

Thank you for your support!

LifeStraw Safe Water Fund

YOU bring real, lasting social change in the Democratic Republic of Congo(DRC). Join us.

“Women are the first victims of war, but only they hold the unique key to peace.” – Julienne Lusenge 
 
 The Fund for Congolese Women (FFC)   supports women's grassroots organizations through financial and technical assistance.  FFC is unique - the only women-led grant-giving NGO in the entire DRC. We provide grants to local women-led organizations that are often in the most remote, difficult to reach areas.   Why? We are unshakable believers in local solutions to local issues.  We know that the brave women and girls working at the grassroots level have the solutions. We know that when women become agents of change, they benefit, their families benefit, their communities benefit. Since its inception in 2007, FFC has funded more than 386 projects throughout the Democratic Republic of Congo. We support projects focusing on eliminating sexual violence against women, delivering empowerment programs for women and girls, educating women about HIV/AIDS and reproductive health, and advocating for environmental justice and access to resources and land for women.  Generous individuals like you make our work possible.  Thank you! 
 
 
 Join the conversation and follow us on Twitter and like us on Facebook.

Fund for Congolese Women (FFC)

Founders Pledge is a global nonprofit empowering entrepreneurs to do the most good possible with their charitable giving. 

Maximize your philanthropic impact with Founders Pledge. We empower a global community of over 2,100 members, equipping them with everything needed to give effectively: from evidence-led research and expert advice on the world's most pressing problems to comprehensive infrastructure for seamless global grant-making, and a powerful network for collaboration. Together, we've already channeled over $1.5 billion to high-impact causes globally, tackling critical issues like climate change, global health, and emerging existential risks. 

When you donate through every.org today, you're joining this proven movement, and our unique funding model ensures 100% of your contribution goes directly to charity, as our operational costs are generously covered by a dedicated community of philanthropists.

Founders Pledge

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We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

Choose a donation for Every.org

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co-founder and previously COO at every.org

.css-1wjgqn{display:inline-block;--textSize:1.5rem;--lineHeight:1.7999999999999998rem;line-height:var(--lineHeight);font-size:var(--textSize);width:100%;}Disease Prevention

Respira Health

Odylia Therapeutics

Mersal Foundation for Charity and Development

Sanku

Founders Pledge & The Life You Can Save: Rapid Response Fund

Mersal Foundation for Charity and Development

Disease Prevention