Fundación Manchitas es una ONG comprometida en esta labor !! Apoyemos !!!

شكراً جزيلاً على كل ما تقدموه

Excellent work and remarkable transparency for a nonprofit

ConnectMyVariants work in the community saves lives! 

People in poverty deserve access to high quality dental care-- and Community Dental Care provides that in a culturally sensitive manner to people of all ages and abilities!

Nonprofit improving animal welfare through low-cost care, rescue, and free adoption of dogs and cats.


Fundación Manchitas is a Panama-based nonprofit organization, dedicated to reducing animal overpopulation and improving public health through **accessible, low-cost sterilization and vaccination services, along with rescue and free adoption of dogs and cats**.

Created in 2020, the foundation works with animals living on the streets and with low-income families, preventing uncontrolled reproduction, reducing the spread of disease, and promoting humane treatment of animals as a shared public health responsibility.

**What They Do**

- **Low-cost sterilization campaigns** to prevent animal overpopulation
- **Vaccination programs** to reduce disease and health risks
- **Rescue and sheltering** of abandoned dogs and cats
- **Free adoption programs** to place animals in safe, permanent homes

**Why It Matters**

Animal overpopulation is both an **animal welfare and public health issue**. By addressing the problem at its source, Fundación Manchitas helps create healthier, safer communities while fostering a culture of respect and responsible care for animals.

**Your Impact**

By donating through **The Resource Foundation**, you support prevention-focused, humane solutions that reduce animal suffering, protect community health, and give rescued animals a second chance. All contributions are **tax-deductible in the U.S.**

Fundación Manchitas

High quality medical services for marginalized groups in Cairo and the region.

Mersal Foundation for Charity and Development is a non-profit organization that serves in the health field and works on providing all types of healthcare with high quality to whoever is in need.

**Vision**
To be the number one medical organization in Egypt and the Arab region and proactive in ensuring the right in healthcare for the marginalized groups and those who are in need the most.

**Message**
Working on analyzing and filling the gaps of the healthcare system to provide high quality medical services on the basis of equality and dignity through enabling a charitable healthcare system for whoever cannot afford it, as well as contributing to the development of the health sector.

**Objectives**  

- Providing medical services to whoever deserves them regardless the cost or for how long they will be needed.
- Spreading medical awareness in all the places it serves in.
- Achieving sustainability in funding its activities Core Values.
- Privacy: Mersal ensures the patient's eligibility to receive its services without hurting their dignity or exposing them to any kind of embarrassment.
- Healthcare With No Discrimination: Mersal is an open arm to all patients with no discrimination whatsover; whatever religion, nationality, color, or language, all patients in need are welcomed to receive the organization services.
- High Quality: Mersal provides all types of medical services in the highest possible quality through its network of specialized medical personnel.
- Credibility and Transparency: Mersal announces the size and sources of its fund as well as its administrative and medical expenditures, The foundation financial reports and annual budgets are available through several outlets through which any person can explore how resources are managed. Mersal believes in the importance of being specialized in specific fields and its early choice was the healthcare services.

In the past six years, the organization registered over 25,000 patients from 27 provinces.  Mersal has been seeking to enable access to its services all over the country. And the dream of helping those who are in need whoever they are and whatever the cost and time is still alive, Mersal has worked over the past six years on getting close to its patients throughout their treatment journey.

Mersal Foundation for Charity and Development 

Delivering medical aid where it's needed most — independent, neutral, impartial.

Doctors Without Borders/Médecins Sans Frontières (MSF) is an international medical humanitarian organization created by doctors and journalists in France in 1971.

In over 70 countries around the world, MSF saves lives by providing medical aid where it is needed most—in armed conflicts, epidemics, natural disasters, and other crises.  The people who work for MSF are doctors, nurses, midwives, epidemiologists, water-and-sanitation experts and many others who combine their professional expertise with a commitment to the world’s most vulnerable people.  Each year, these medical teams run close to 470 projects where they care for millions of people.  

As an organization, MSF is neutral and operates independently of any political, military, or religious agendas. It does not take sides in armed conflicts, provides care based on needs alone, and advocates for increased independent access to victims of conflict and disaster as required under international humanitarian law. Medical teams conduct evaluations on the ground to determine a population's medical needs before opening programs, aiming to fill gaps that exist (rather than replicating services that are already offered) or reach communities that are not being assisted.  Over the years, the organization has been the recipient of several awards that recognize its work, including the 1998 Conrad N. Hilton Humanitarian Prize, the 1999 Nobel Peace Prize, the 2012 J. William Fulbright Prize for International Understanding, the 2015 Lasker-Bloomberg Public Service Award, and the 2017 Pardes Humanitarian Prize for Mental Health.

Doctors Without Borders/Médecins Sans Frontières (MSF) 

ConnectMyVariant's mission is to end hereditary disease by bringing families together.

ConnectMyVariant is an educational health-focused 501(c)3 nonprofit organization that supports individuals and families with hereditary disease in their early detection and prevention efforts. We provide unique value by leveraging our evidenced-based family connection protocols to help people identify other at-risk relatives and help those relatives access genetic testing so that they can get optimal medical care. ConnectMyVariant brings people with the same genetic risk together through our variant database and community engagement events to share experiences and find common ancestors. ConnectMyVariant also works to increase awareness of the benefits of family outreach among physicians, others who provide prevention care, and the broader genealogy community.
 
Our key activities are:

- Working with patients to implement personalized family outreach plans
- Interactive educational workshops about sharing information on inherited disease risk
- Variant specific family reunions to share stories and plan outreach to cousins
- Genealogy assistance to help connect individuals in variant groups
- Individual equity and inclusion grants for family and community outreach

Need and Impact:
When hereditary disease risk is known, family outreach has been proven to be the most effective and cost-effective intervention for early detection and prevention. This family outreach, also known as cascade testing, is recommended by multiple guidelines. Despite overwhelming evidence, family outreach assistance is not reimbursed by insurance or integrated into healthcare. Many people suffer and die from hereditary disease that could have been prevented or caught early.
 
We have shown that our strategies to encourage family outreach can act as a communication multiplier. Our pilot research at the University of Washington showed that this approach enhanced patient experience, was considered ethical, and was appreciated by newly identified relatives. Our approach is low-cost and is 25 to 50 times more effective than awareness and education interventions that target the general population.

Equity and Inclusion:
ConnectMyVariant is committed to being a leader for equity, diversity, and inclusion in hereditary disease prevention. ConnectMyVariant’s goal is to spread awareness among all individuals and families about inherited disease risk. All project staff, participants, and partners in ConnectMyVariant have an equal voice in developing innovative ways to improve hereditary disease outreach and prevention for all people. By fostering a diverse and inclusive community, we can provide knowledge and opportunities that have been historically inaccessible to millions of people.

ConnectMyVariant

We provide comprehensive oral health care for people in need of all ages. Serving 50,000 patients annually at 5 clinics in MN. 

Our mission is to provide culturally sensitive community oral health care, preventive education, professional training, and to advocate for access for all. 

Our vision is that all people will have access to high quality, affordable dental care to improve their overall health in a convenient, caring, and respectful environment.

We are a nonprofit organization, and we serve patients from all walks of life and economic circumstances. We want to make high-quality dentistry available to anyone who needs care. We have over 200 dedicated employees, including dentists, hygienists, assistants, and an administrative team who are continually improving care and delivering the best possible dentistry.

Community Dental Care

Young Tongues supports tongue cancer patients diagnosed aged 18–64 worldwide. 

Young Tongues exists because younger adults diagnosed with tongue cancer were being left without the support, understanding or resources they urgently needed. When our founder, Barbara Fountain, was diagnosed at 32, she discovered there was no community for younger patients, no age-appropriate information and no guidance that reflected the realities of working, parenting, relationships or identity at this life stage.

That gap wasn’t unique to her — it was happening everywhere.

Today, Young Tongues is the only organisation in the world dedicated specifically to people diagnosed aged 18–64 facing tongue cancer, a group whose numbers are rising quickly. Through digital peer support groups, monthly virtual meet-ups, in-person gatherings and a growing global network, we bring together patients and their supporters from across the globe to ensure no one feels alone in their experience.

Thanks to donors, we provide practical, trustworthy, clinically reviewed resources; a widely appreciated podcast sharing real stories; and direct partnerships with researchers and clinicians to ensure younger patients’ experiences shape the future of diagnosis, care and treatment. We also speak internationally to help healthcare professionals recognise symptoms sooner and understand the distinct challenges this age group faces.

Our next major initiative is the Young Tongues Patient Hub - a new website that makes finding clinically safe information written from a patient perspective more accessible AND the Young Tongues Patient Insight Platform — a global project to turn lived experiences into evidence powerful enough to influence research, improve care and support earlier diagnosis. This is a bold step forward, but it can only happen with donor support.

Young Tongues receives no government funding. It costs around £60,000 a year just to maintain our current work. Every donation has a direct impact: keeping our support groups running, expanding our resources, accelerating vital advocacy and helping us build the systems younger adults desperately need.

Your support helps make sure no young person faces tongue cancer in isolation and that the future of care for this growing group is built on understanding, compassion and evidence.

**US-based donors**

*U.S.-based donors can make tax-deductible contributions to the \**Young Tongues Fund*\* at Myriad USA. Because Myriad USA is a public charity, within the meaning of Sections 501(c)(3) and 509(a)(1) of the IRC, donors may claim the maximum tax benefits allowed by U.S. tax law for their contributions. If you wish to support us, here is how to proceed:*

- *Gifts by check: Address your check to Myriad USA, write \**Young Tongues Fund*\* in the memo section of the check, and send it to Myriad USA at 551 Fifth Avenue, Suite 2400, New York, NY 10176*
- \*Gifts by credit card on this page: [**https://www.every.org/young-tongues/f/fund-the-foundations**](https://www.every.org/young-tongues/f/fund-the-foundations)\*
- *Gifts by wire transfer or to contribute other types of property: Contact Myriad USA via email at [donations@myriadusa.org](mailto:info@myriadusa.org) or phone (212) 713-7660.*

Young Tongues

Tent City Showers is a nonprofit dedicated to caring for our city's homeless with dignity and compassion. 

Tent City Showers is a grassroot non profit delivering hot showers to the homeless community in Columbus Ohio. A fresh haircut provides confidence and a new look. The barber chair is always a great place to make a human connection and talk about what God is doing. We encourage people to sit at our table and eat all the hot dogs they want and take a few with you. A full set of clothes and an essential care kit is provided to each person who showers. 

Tent City Showers has one trailer with 3 showers. All 3 showers run non stop when we go out and the trailer reaches it full potential. We have acquired a full size school bus that will converted into an 8 shower mobile homeless resource center. Each trip out the bus will provide up to 100 showers, 500 hotdogs, and a climate controlled barber shop. 


Tent City Showers

We provide cash incentives for childhood vaccinations. It’s one of the most cost-effective ways known to save lives.


New Incentives’ mission is to save lives in a way that does the **most good per dollar**.
Guided by evidence, we provide cash incentives to increase childhood vaccination rates.

- We [raise awareness](https://www.newincentives.org/blog-posts/awareness-activities) about the benefits of childhood vaccinations.
- We [provide cash incentives](https://www.newincentives.org/blog-posts/a-day-in-the-life-abubakar-aliyu-field-officer) at government clinics after children receive vaccinations.
- We [help improve the vaccine supply chain](https://www.newincentives.org/blog-posts/supporting-government-partners-with-vaccine-supply-efforts) to ensure enough vaccines are available at clinics.

Together, these efforts are proven to double vaccination rates and save lives.
Learn more about the [randomized controlled trial](https://www.newincentives.org/rct-results).

As of March 2024, New Incentives has reached more the 3 million infants in northern Nigeria.

New Incentives

Not for profit, founded as a 501C3 charity in 2006 in NYC. Providing Health, Education, and Empowerment opportunities.

Our cornerstone project was building East & Central Africa's 1st Public Children's Hospital.  Since opening in 2015, we have treated over 1.3 million kids. The impact does not end there, we have also constructed six public (free-to-attend) schools, a dairy project, a kids community house and more. We also run a vibrant Women's Empowerment Project focusing on agri-biz and domestic violence survivors.  Our latest major project is constructing the first children's cancer hospital in sub-Saharan Africa.

visit our Learn About Us page on shoe4africa.org

Shoe4Africa

We target opportunities where small investments can generate extraordinary impact and create lasting change.

There are many charities that address global poverty and suffering. 

With our Global Health & Development (GHD) **Catalytic Impact Fund**, we try to find the strategic pressure points where modest funding unlocks transformational change. 

By prioritizing these leverage points, we help donors maximize their impact in building sustainable, long-term solutions to global poverty and suffering — saving and improving as many lives as possible with each dollar.

What does catalytic impact look like?

- **We trigger systemic improvements**: We support investments that create new long-term infrastructure or increase the cost-effectiveness of existing systems.
- **We remove key bottlenecks**: We identify and remove barriers that stand in the way of accelerated impact.
- **We crowd in capital**: We provide early-stage funding that attracts substantial follow-on investment for cost-effective opportunities.

### Our Approach to Grantmaking

When evaluating potential grants, we consider several key points:

- **Counterfactual impact**. Our grants are designed to create meaningful outcomes that would not otherwise have happened. This means that you can rely on the Funds to create meaningful, real change, rather than just maintaining the status quo.
- **Impact-driven philanthropy**. This fund prioritizes the highest-impact solutions to challenges. We assess where the gaps are, which opportunities may be neglected by other funders, and where the biggest wins are in terms of making the biggest difference.
-  **The organization’s funding gap**. Not all organizations are set up to scale programs and some may not be able to productively absorb large amounts of unsolicited funding at any given point. We evaluate all potential grantees’ capacity for growth and consider how much money they could put to good use.
-  **Organizational strength**. Particularly with unrestricted funding, it’s important to have trust in the leadership and capacity of the organizations we support. We look at their track record of success and their transparency about failures as well as successes, and we only support those organizations which are exceptionally well run.
- **Time-critical opportunities and funding certainty**. Sometimes there are time-critical opportunities which require fast decisions. We will use the Fund to make grants that enable such short-term opportunities and stability for high-impact funding opportunities thereby increasing the impact compared to individual giving to specific organizations.

### Frequently-Asked Questions

**Can charities apply for money from the Fund?**

Founders Pledge reviews [requests for funding](https://www.founderspledge.com/requests-for-funding) from organizations, but does not guarantee we can fill funding requests.

**How frequently will you make grants from the Fund?**

In general, Fund Managers will review grantmaking decisions on a quarterly basis, based on the value of Funds and the available options for high-impact grantmaking. We may disburse funds outside of quarterly review dates if we become aware of a particularly promising and time-sensitive funding.

**How will my contribution be used?**

All funds are granted out — every dollar contributed to the Fund will be used to make grants directly to end-user organizations creating a real difference.

### More Questions?

To learn more about the Founders Pledge GHD Catalytic Impact Fund, please visit [founderspledge.com](https://founderspledge.com/funds/global-health-and-development-fund) or email the team at [funds@founderspledge.com](mailto:funds@founderspledge.com).

Founders Pledge: GHD Catalytic Impact Fund

Odylia Therapeutics is a nonprofit biotech working to accelerate the development of treatments for people with rare diseases.

At Odylia, we accelerate therapeutic development for people with rare diseases, changing the way treatments are brought from the lab to the clinic. We strive to bring life altering treatments to people with genetic disease regardless of prevalence or commercial interest. 
Odylia is shifting the paradigm to focus on proven science and removing traditional roadblocks. We work to lower costs, reduce development time, focus research, and continuously drive successful programs towards clinical trials and regulatory approval. Strategic collaborations with patient groups, research labs, and commercial partners facilitate our work to ensure treatments are safe, effective, and ultimately reach patients who need them.

Odylia challenges the traditional approach to drug development through:

1. Lower cost of development
Lower licensing fees to decrease development costs and ensure continued commitment to program success
2. Increase speed of development
Challenge traditional approaches through regulatory engagement

Streamline development through strategic partnerships and a platform approach to drug development

3. Enable the entire ecosystem
Provide expertise through in-house Brydge Solutions and leveraging the Odylia Board

Enable the entire ecosystem through Initiatives that impact the broader field

Odylia Therapeutics

An organization focused on diseases, disorders, and medical disciplines. It received its nonprofit status in 2022.

Preventable and curable diseases persist in neglected populations because quality medicines fail to reach those in need. Though treatments exist, low supply, poor packaging, and counterfeit drugs reduce trust and coverage in low- and middle-income countries.

We address this by producing essential medicines in short supply and improved medicines for mass drug administration. Our drugs are reliable, high-quality, and packaged in child-resistant, tamper-evident, and eco-friendly materials that are easy to understand.

**At Bend Biomedical, we believe everyone deserves quality medicine. Period.**

Bend Biomedical

Prevention, control and treatment of malaria and other communicable diseases among vulnerable populations.

Malaria Consortium US, Inc. (MC-US) is a registered 501(c)(3) public charity and shares the mission of Malaria Consortium, a globally recognized organization committed to reducing deaths and illnesses caused by malaria and other preventable and treatable diseases across Africa and Asia.

Our mission is to save lives and improve health in Africa and Asia through evidence-based programs that tackle malaria and other priority diseases while advancing universal health coverage (UHC). In the US, we build partnerships with foundations, donors, and philanthropic organizations to ensure that every contribution makes a lasting impact for those most in need.

As a leader in malaria control and elimination, our work focuses on interventions such as seasonal malaria chemoprevention (SMC), malaria vaccines, disease surveillance, and integrated child health services. We work in collaboration with governments, communities, and health systems to improve access to essential healthcare and strengthen delivery of services in underserved and hard-to-reach areas.

As a leader in interventions such as chemoprevention and vector control, we rely on evidence and our expertise to deliver established interventions, influence other effective interventions and guide new strategies to reduce the burden of malaria, pneumonia, dengue, malnutrition and diarrhea. We work with communities and all levels of the health system to improve access to and demand for primary healthcare services and overall quality of care.

Our tailored interventions seek to improve equity by providing quality, affordable health services to marginalized populations (particularly women and girls and those living in hard-to-reach areas). To ensure barriers to achieving UHC are addressed and to encourage sustainability, we work closely with governments to integrate our programs within existing health systems and structures in the countries in which we work.

We promote disease surveillance as a core intervention to engage communities to improve the quality and accessibility of routine health information by using digital tools and approaches that strengthen the linkages between case-level data and national health information systems. We combine capacity development at community level with the use of innovative tools and platforms to enhance local capabilities to interpret and use these data most effectively.

All of our work is informed by our core values: accountability, integrity, dignity and equity.

Malaria Consortium

One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

Founders Pledge is a global nonprofit empowering entrepreneurs to do the most good possible with their charitable giving. 

Maximize your philanthropic impact with Founders Pledge. We empower a global community of over 2,100 members, equipping them with everything needed to give effectively: from evidence-led research and expert advice on the world's most pressing problems to comprehensive infrastructure for seamless global grant-making, and a powerful network for collaboration. Together, we've already channeled over $1.5 billion to high-impact causes globally, tackling critical issues like climate change, global health, and emerging existential risks. 

When you donate through every.org today, you're joining this proven movement, and our unique funding model ensures 100% of your contribution goes directly to charity, as our operational costs are generously covered by a dedicated community of philanthropists.

Donate this Giving Season and we'll match your donation up to a value of $750,000, until Dec 31.

Founders Pledge

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We are a nonprofit, so instead of charging fees we rely on the generosity of donors like you.

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Fundación Manchitas

ConnectMyVariant

Mersal Foundation for Charity and Development

Community Dental Care

Doctors Without Borders/Médecins Sans Frontières (MSF)

Mersal Foundation for Charity and Development

Disease Prevention