We need to scale up new effective charities. I have a ton of respect for their approach, especially after hearing that they shut down their No Lean Season after collecting evidence that showed lower impact than hoped-for: https://www.vox.com/future-perfect/2019/6/7/18654620/evidence-action-no-lean-season-givewell

Malaria Consortium

Protecting sight and fighting for disability rights

Sightsavers works in more than 30 countries worldwide, focusing on Africa and Asia.
We work with local, regional, national and international partners and governments. With their help, we distribute treatments to prevent disease, carry out eye operations, advocate for disability rights and improve health services to create sustainable development projects. 

Our vision is of a world where avoidable blindness is eliminated, and people with disabilities have the same rights as everyone else. We can only get there thanks to the generosity of our supporters, so we aim to be as transparent as possible so you can be sure your money is being used wisely.

Sightsavers

The END Fund is the only private philanthropic initiative solely dedicated to ending the most common neglected tropical diseases.

Our Mission: To control and eliminate the most prevalent neglected tropical diseases (NTDs) among the world's most vulnerable communities and people by 2030. 


NTDs are a group of parasitic and bacterial diseases largely prevalent in tropical regions that currently receive little attention on the global health agenda yet have a significant impact hampering the potential of individuals and communities at large. The devastating effects of NTDs include irreversible blindness, severe disfigurement, stunted cognitive and physical development, especially in children, malnutrition, social isolation, and more. NTDs also cause 170,000 deaths per year. Their comprehensive impact on all aspects of daily life means that the presence of NTDs costs affected countries billions of dollars per year in lost productivity, out-of-pocket expenses, and reduced socioeconomic and educational attainment. 

Currently, 1.7b individuals are affected by such diseases. However, the treatments and knowledge required to eliminate these diseases are readily available, with the annual cost of treatment per individual averaging 50 cents per year. Demonstrating the uniquely cost-effective impact of NTD treatment, studies have shown treatment is the single most efficient means of improving children’s school attendance and capacity to learn. A recent report by Deloitte on Nigeria showcases the significant gains affected economies stand to make should NTDs be eliminated, with Nigeria’s economy estimated to receive an $18.9b boost from now until 2030. The report is available to view here - https://www2.deloitte.com/za/en/nigeria/pages/strategy/articles/Ending_The_Neglect.html

The END Fund helps ensure those at risk of NTDs need not experience such preventable suffering but can live healthy and prosperous lives instead. We do so by working in close partnership with stakeholders across the global NTD community to identify and fulfill gaps and needs in NTD funding, design programs, strengthen the capacity of local actors, provide technical support, and assist with monitoring and evaluation, amongst various additional activities. Our work helps children stay healthy and in school, prevents advanced cases that cause disability and restrain individuals' productive potential, and alleviates the disproportionate disease burden faced by women and girls, as well as the economic burden of disease on families. We have distributed more than 1.2b treatments since our founding in 2012, with 118m individuals treated in 2021 alone.

We envision living in a world in which all have the opportunity to achieve their full potential, with these diseases that have plagued humans for millennia confined to history once and for all.

The END Fund

Evidence Action scales evidence-based and cost-effective programs to reduce the burden of poverty. 

Evidence Action was founded in 2013 to address a big gap in the fight against global poverty – many of the most promising interventions are either implemented at a very small scale, or not at all. We set out to address this gap by building programs that would scale evidence-based and cost-effective interventions, leading to significant improvements in quality of life for hundreds of millions of people.

Our model worked. Since then, our interventions have reached more than 530 million people. This success is achieved through the dedication and talent of our staff, the hard work of our partners, and the commitment of our supporters.

Our Accelerator is the engine for our new program development. To find the most cost-effective solutions in the world, we explore untapped opportunities with the greatest potential for impact. Through a rigorous process, we test groundbreaking health and development interventions, selecting those with a proven ability to reduce the burden of poverty at scale. This focus allows us to maximize the impact made for every single dollar invested.

**Programs:**

**Safe Water Now**

We provide sustained safe water access to communities through water treatment – one of the most cost-effective ways to prevent childhood illnesses and death. Safe Water Now programming in Kenya, Uganda, Malawi, and India uses innovative, low-cost approaches like chlorine dispensers and automatic in-line chlorination. With local government and community buy-in, we reach nearly 10 million people with safe water access and have saved the lives of more than 15,000 children under 5 years old. Now, we are scaling in partnership with the Government of India to reach tens of millions more.

**Deworm the World** 

We help improve children's health, education, and long-term wellbeing by treating parasitic worm

infections at schools. In partnership with governments in Kenya, Nigeria, India, and Pakistan, Evidence Action designs, scales, and sustains cost-effective mass deworming programs. Since 2014, Deworm the World has helped governments deliver 2 billion deworming treatments to children, dramatically reducing worm prevalence and collectively increasing economic productivity by an estimated $23 billion USD.

**Equal Vitamin Access**

We combat the leading cause of childhood malnutrition and disability in low- and middle-income countries by helping to deliver essential supplementation. Equal Vitamin Access provides end-to-end support to governments in India and Malawi to address anemia by leveraging our school-based deworming platform to offer iron and folic acid supplementation cost effectively. In 2023 alone, our program reached 35.8 million children with weekly treatments, giving them a

better chance to develop into strong, healthy adults.

**Syphilis-Free Start**

We safeguard the health of pregnant women and their unborn children by enabling access to low-cost syphilis screening and treatment as part of prenatal care. We partner with governments in Liberia, Cameroon, and Zambia to prevent disability, neonatal

mortality, and stillbirths resulting from congenital syphilis. Syphilis-Free Start’s timely detection and treatment prevented 2,300 adverse outcomes such as blindness, neurological issues, and hearing loss between 2021 and 2023, including 1,300 lives saved.



Evidence Action

Developing the roadmap for a sustainable, secure, and just global protein supply 🧫🌱


Check out what your support makes possible at gfi.org/your-impact. 

The Good Food Institute (GFI) is a global network of nonprofit organizations developing the roadmap for a sustainable, secure, and just protein supply. Industry alone will not meet this challenge at the scale or speed we need. GFI is accelerating the transformation of the food system by identifying solutions and mobilizing resources to make alternative proteins the default way meat is made.

GFI is a network of nonprofits around the world strategically based in the most critical economies for alternative protein advancement. In Asia, Europe, Brazil, India, Israel, and the U.S., GFI’s teams are mobilizing the international community to use markets and technology to replace harmful practices with ones that are better for the climate and biodiversity, for food security, and for global health.

GFI’s Focus
As a nonprofit, GFI is uniquely positioned to accelerate the transition to alternative proteins by focusing on three programmatic priorities:

-Cultivating a strong scientific ecosystem | GFI’s science and technology teams map out the most neglected areas that will allow alternative proteins to compete on taste and price. GFI meets these challenges by developing open-access research and resources, educating and connecting the next generation of scientists and entrepreneurs, and funding research that benefits alternative protein development across the sector. 

-Influencing policy and securing government funding | GFI’s policy teams ensure that alternative proteins are a part of the policy discussion around climate change mitigation and global health. In every region where GFI has a presence, teams advocate for government funding and incentives to transition to alternative proteins and are paving the way for the approval of novel proteins such as cultivated meat.

-Ensuring industry prioritizes alternative proteins | GFI’s corporate teams are creating a transformation of our global meat supply. GFI works to replicate past market transformations by showing companies of all sizes, from startups to multinational corporations, how alternatives to animal products can be profitable while meeting environmental, social, and governance goals.

Reimagining meat
The very real threats of climate change, global food insecurity, antibiotic resistance, and pandemics require us to imagine a different future of food. Alternative proteins are the solution that will securely and sustainably feed the world.

GFI’s global community of scientists, policy experts, and corporate specialists are creating a world where alternative proteins are no longer alternative.



The Good Food Institute

We research and advise on the legal challenges posed by artificial intelligence.

The Institute for Law & AI (LawAI) is an independent think tank that researches and advises on the legal challenges posed by artificial intelligence. We believe that sound legal analysis will promote security, welfare, and the rule of law.

Would you like to learn more or talk to us? You can always [contact us](https://law-ai.org).

Thank you for your support!

Institute for Law & AI

WANBAM

StrongMinds provides life-changing mental health services to women in Africa using innovative community-based group therapy.

According to the WHO, depression is the leading cause of disability worldwide, and is a major contributor to the global burden of disease. In Africa, an estimated 66M women have depression and 85% have no access to treatment. Since 2014, StrongMinds has treated over 200,000 individuals for depression symptoms, with 80% measuring as depression-free after therapy. When a woman recovers from depression, she is more engaged in the community and her economic activity increases. Her family eats more meals and her children go to school more often. When you invest in mental health, you invest in the future of an individual, their family, and their community.

StrongMinds Inc

Lowering the entry point and barriers into starting a nonprofit project initiative for philanthropists globally.

Players Philanthropy Fund (PPF), founded by NFL Legend Matt Stover, stands tall as the nation's premier facilitator and administrator of charitable funds for athletes, celebrities, and philanthropists alike.

At PPF, we believe in the power of dedicated charitable projects to transform lives and communities. That's why we provide a seamless platform for philanthropists to create and manage their charitable initiatives, all while enjoying the benefits of tax-deductible contributions. Whether you're a private individual, a renowned athlete, an entertainer, a corporation, or any other entity with a charitable mission, PPF is here to turn your vision into reality.

As proud fiscal sponsors, we offer unparalleled support and expertise to ensure that your charitable endeavors thrive. From setting up funds to navigating regulatory compliance, our dedicated team is with you every step of the way, empowering you to make a meaningful difference in the world.

Join us at PPF and unlock the full potential of your philanthropy. Together, let's create lasting change.

Players Philanthropy Fund - PPF

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