The Future of Life Institute is doing valuable work to reduce global catastrophic and existential risks from powerful technologies that I believe are likely to be developed this century.
Future of Life Institute
Winchester, MAFLI catalyzes and supports research and initiatives for safeguarding life and developing optimistic visions of the future.
Givewell is the best charity ranker according to The New York Times. They distribute this fund among the best charities according to who needs it most in a given month.
Top Charities Fund
Oakland, CAThe Top Charities Fund supports the highest-priority funding needs among our top charities.