One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

Delivering unconditional cash directly to the world's poorest households via secure mobile transfers. 

Since 2009, GiveDirectly has delivered more than $580 million in unconditional cash transfers to families in need. These one-time cash transfers allow recipients to invest in what they need most and have been shown to improve their earnings, children’s school attendance, health, nutrition, and mental well-being.
 
GiveDirectly uses government data to target villages where most or all residents are living in extreme poverty, defined by the World Bank as earning under $2.15/day. In-country GiveDirectly staff enroll one member of each household in the entire village to receive a one-time transfer of about $1,000 USD sent in two installments using mobile money. Recipients can then withdraw the mobile funds as cash with local agents and use the funds to invest in what they need – whether it’s on starting a business, education, making their home safer/sturdier, healthcare, or livestock.
 
GiveDirectly uses rigorous experimental research (randomized controlled trials) to measure the impact of their unconditional cash programs and answer public policy questions, generating evidence on key design and implementation questions across varied contexts. You can find over 300 studies on the positive impacts of cash transfers in GiveDirectly’s Cash Research Explorer.

GiveDirectly

Works to exonerate innocent people through DNA testing and reform the criminal justice system to prevent injustice.

The Innocence Project was founded in 1992 by Barry C. Scheck and Peter J. Neufeld at the Benjamin N. Cardozo School of Law at Yeshiva University to assist prisoners who could be proven innocent through DNA testing. More than 350 people in the United States have been exonerated by DNA testing, including 38 who pleaded guilty to crimes they did not commit and 20 who served time on death row. The Innocence Project provided direct representation or critical assistance in more than 200 exonerations.   The Innocence Project’s full-time staff attorneys and Cardozo clinic students provide direct representation or critical assistance in most of these cases. The Innocence Project’s groundbreaking use of DNA technology to free innocent people has provided irrefutable proof that wrongful convictions are not isolated or rare events but instead arise from systemic defects. Now an independent nonprofit organization closely affiliated with Cardozo School of Law at Yeshiva University, the Innocence Project’s mission is nothing less than to free the staggering numbers of innocent people who remain incarcerated and to bring substantive reform to the system responsible for their unjust imprisonment.  With the generous support of individuals like you the Innocence Project has exonerated scores of innocent people and worked around the country to reform our criminal justice system. With the generous support of individuals like you the Innocence Project has exonerated scores of innocent people and worked around the country to reform our criminal justice system.

Innocence Project

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