One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

Prevention, control and treatment of malaria and other communicable diseases  among vulnerable populations.

Our mission is to improve lives in Africa and Asia through sustainable, evidence-based programs  that combat targeted diseases and promote child and maternal health. 

We will accomplish this together with partners and all levels of government, by:

designing and implementing cutting edge research, surveillance and monitoring and evaluation;
selectively scaling up and delivering sustainable evidence-based health programmes;
providing technical assistance and consulting services that shape and strengthen national and international health policies, strategies and systems and build local capacity;
seeking to ensure that our experience, thought leadership, practical findings and research results are effectively communicated and contribute to the coordinated improvement of access to and quality of healthcare. 
Our areas of expertise include: 
disease prevention, diagnosis and treatment
disease control and elimination
health systems strengthening
research, monitoring and evaluation leading to best practice
behavior  change communication
national and international advocacy, and policy development


Malaria Consortium

The Top Charities Fund supports the highest-priority funding needs among our top charities.

We find and recommend outstanding giving opportunities and publish our research to help donors give more effectively and with greater confidence.

All donations here support our Top Charities Fund. Donations to the Top Charities Fund are granted on a rolling basis to support cost-effective funding opportunities at our top charities. We use our latest research to grant the funds to the top charity (or charities) where we believe they’ll do the most good.

Learn more and view past grants at https://www.givewell.org/top-charities-fund


Photo caption: At health centers in Sierra Leone supported by Helen Keller Intl, mothers who bring their children in for twice-yearly vitamin A supplemention can also receive comprehensive counseling about birth control options that are available to them free of charge. Combining family planning and children's healthcare services benefits both mother and child. 2019.

Top Charities Fund

FLI catalyzes and supports research and initiatives for safeguarding life and developing optimistic visions of the future.

To catalyze and support research and initiatives for safeguarding life and developing optimistic visions of the future, including positive ways for humanity to steer its own course considering new technologies and challenges.

Future of Life Institute

We do foundational mathematical research to ensure smarter-than-human artificial intelligence has a positive impact.

The Machine Intelligence Research Institute is a research nonprofit studying the mathematical underpinnings of intelligent behavior. Our mission is to develop formal tools for the clean design and analysis of general-purpose AI systems, with the intent of making such systems safer and more reliable when they are developed.

The field of AI has a reputation for overselling its progress. In the “AI winters” of the late 1970s and 1980s, researchers’ failures to make good on ambitious promises led to a collapse of funding and interest in AI. Although the field is now undergoing a renaissance, overconfidence is still a major fear; discussion of the possibility of human-equivalent general intelligence is still largely relegated to the science fiction shelf.

At the same time, researchers largely agree that AI is likely to begin outperforming humans on most cognitive tasks in this century. Given how disruptive domain-general AI could be, we think it is prudent to begin a conversation about this now, and to investigate whether there are limited areas in which we can predict and shape this technology’s societal impact.

Researchers at MIRI tend to be relatively agnostic about how the state of the art in AI will change over the coming decades, and how many years off smarter-than human AI systems are. 

Machine Intelligence Research Institute

We connect and support a network of women, trans people of any gender, and non-binary people interested in Effective Altruism.

Effective Altruism is about answering the question, "How can we use our resources to help others the most?" We believe that to solve this question, we need incredible people with a diversity of skills and perspectives.

We started WANBAM because we identified an opportunity for a high-leverage, positive impact. In 2019, 71% of respondents to the EA Survey reported their gender as male. Additionally, the survey found women twice as likely to cite a lack of diversity or welcomingness as a barrier to greater involvement in EA. Personal contact was overwhelmingly the most important factor for retention, especially for women. This pointed toward the value of mentorship to complement and support EA community-building efforts in attracting and retaining dedicated, talented people.

WANBAM was founded with the aim of inspiring and supporting women, trans people of any gender, and non-binary people pursuing high-impact career paths. Since late 2019, we have matched and facilitated the mentoring of over 230 people. Our mentor base has quickly grown to over 90 people from a diversity of organizations. You can find out more about our successes, challenges, and opportunities for impact in Kathryn, our CEO’s talk at EAGX Asia Pacific, below.

WANBAM

We conduct and support legal research that mitigates existential risk and promotes the flourishing of future generations.

Support our mission to conduct strategic legal research that mitigates existential risk and promotes the flourishing of future generations, and to build a field that shares these priorities.

You can read our Annual Report for 2022 (including our plans for 2023) here: https://www.legalpriorities.org/blog/2023/lpp-annual-report-2022/

We currently focus on four cause areas: Law and governance of advanced artificial intelligence, biosecurity & pandemic preparedness, institutional design, and meta-research.

- Our Goals -
Strategic Research: Our primary goal is to conduct strategic research that can be used by legal actors—for example, policy makers, judges, and litigators—working on the world’s most pressing problems. Our research focuses on mitigating existential risk and promoting the flourishing of future generations.

Field Building: We aim to raise awareness about our concern for the long-term future and build a field that shares these priorities. We want to bring together researchers and policy-makers at every level of seniority and support the most effective ways to use the law to protect future generations and mitigate existential risk. 

You can find our full research agenda here: https://www.legalpriorities.org/research/research-agenda

To learn more about our previous successes, you can also browse through our newsletters here: https://us17.campaign-archive.com/home/?u=2bb7ad9a08b210b8e814dd0b5&id=798222e74e

Would you like to learn more or talk to us? You can always contact us: https://www.legalpriorities.org/contact

Thank you for your support!

Legal Priorities Project

The world's-first funding vehicle to collectively grow our resources to support the long-term flourishing of humanity. 


This Project focuses on how we can collectively grow our resources to support the long-term flourishing of humanity. It addresses a crucial gap: as a society, we spend much too little on safeguarding and benefiting future generations. In fact, we spend more money on ice cream each year than we do on preventing our own extinction. However, people in the future - who do not have a voice in their future survival or environment - matter. Lots of them may yet come into existence and we have the ability to positively affect their lives now, if only by making sure we avoid major catastrophes that could destroy our common future.

Housed within the Project is the Patient Philanthropy Fund, a philanthropic co-funding vehicle which invests to give and ensures capital is at the ready when extraordinary opportunities to safeguard and improve the long-term future arise.

The Fund’s patient approach means that we aim to identify the point in time when the highest-impact opportunities are available, which may be years, decades, or even centuries ahead.

Here’s how it works:  

- Donors contribute to the Fund to create a shared pool of capital
- Capital is invested for long-term gains, initially in a low-fee Global Stock Index Fund
- While the fund grows, more research is conducted into future-focused funding opportunities and optimal timing of giving
- When an extraordinary time, need or opportunity arises, the Fund steps in 

This is very much a long-term project that will be nurtured and developed as the Fund grows. We have several milestones in place, including an investment strategy update when the Fund hits $10m. And when the Fund reaches $100m, or after 10 years (with a minimum $10m AUM), it will spin out and become an independent entity.

Get involved

We’ve secured over $2m in funding from our generous Founding Partners and Supporters, including Jaan Tallinn (Co-founder of Skype), Ignaz Forstmeier (Co-founder of Personio), Austin Che (Founder of Ginkgo Bioworks), and Andrew White (Founder of FundApps), among others. 

The Fund is managed by a committee of experts, all with a strong network and expertise on how well-timed grantmaking can safeguard the future:

- Philip Trammell (Research Associate at Oxford’s Global Priorities Institute and DPhil student in economics, Oxford)
- Luke Ding (Board Member at Founders Pledge and advisor to the Effective Altruism Infrastructure Fund)
- Sjir Hoeijmakers (Research Director at Giving What We Can)
- Max Daniel (Senior Program Associate at Open Philanthropy and Chair of the Effective Altruism Infrastructure Fund)
- Eva Vivalt (Director at Oxford’s Global Priorities Institute)




Founders Pledge: Patient Philanthropy Fund

The Centre for Effective Altruism helps to grow and support the effective altruism community.

Effective altruism is about using evidence and reason to figure out how to benefit others as much as possible, and taking action on that basis.

The Centre for Effective Altruism (CEA) is a charity dedicated to building and nurturing a global community of people who are thinking carefully about the world’s biggest problems and taking impactful action to solve them.

We hope that this community can help to build a radically better world: by connecting students and young professionals with relevant experts, we can help them consider their values and find an effective way to contribute that is a good fit for their skills and inclinations.

Centre for Effective Altruism USA

We search for the charities that save or improve lives the most per dollar.

Our goal is to produce the world's top research on where to give. Free, for everyone.

We recommend a small number of charities that do an incredible amount of good. 

If you would like to donate to our giving funds or individual top charities, please see our projects below. You can donate here or on the Unrestricted Fund page below to make an unrestricted gift to GiveWell to support the full spectrum of our grantmaking and underwrite our ability to continue doing what we do.