Prevention, control and treatment of malaria and other communicable diseases  among vulnerable populations.

Our mission is to improve lives in Africa and Asia through sustainable, evidence-based programs  that combat targeted diseases and promote child and maternal health. 

We will accomplish this together with partners and all levels of government, by:

designing and implementing cutting edge research, surveillance and monitoring and evaluation;
selectively scaling up and delivering sustainable evidence-based health programmes;
providing technical assistance and consulting services that shape and strengthen national and international health policies, strategies and systems and build local capacity;
seeking to ensure that our experience, thought leadership, practical findings and research results are effectively communicated and contribute to the coordinated improvement of access to and quality of healthcare. 
Our areas of expertise include: 
disease prevention, diagnosis and treatment
disease control and elimination
health systems strengthening
research, monitoring and evaluation leading to best practice
behavior  change communication
national and international advocacy, and policy development


Malaria Consortium

We implement projects aimed at doing the most good in terms of reducing suffering.

Most of us want to make a difference. We see suffering, injustice and death, and are moved to do something about them. But working out what that ‘something’ is, let alone actually doing it, can be a difficult and disheartening challenge.

Effective altruism is a response to this challenge. It is a research field which uses high-quality evidence and careful reasoning to work out how to help others as much as possible. It is also a community of people taking these answers seriously, by focusing their efforts on the most promising solutions to the world's most pressing problems.

Effective Altruism Foundation 

We do foundational mathematical research to ensure smarter-than-human artificial intelligence has a positive impact.

The Machine Intelligence Research Institute is a research nonprofit studying the mathematical underpinnings of intelligent behavior. Our mission is to develop formal tools for the clean design and analysis of general-purpose AI systems, with the intent of making such systems safer and more reliable when they are developed.

The field of AI has a reputation for overselling its progress. In the “AI winters” of the late 1970s and 1980s, researchers’ failures to make good on ambitious promises led to a collapse of funding and interest in AI. Although the field is now undergoing a renaissance, overconfidence is still a major fear; discussion of the possibility of human-equivalent general intelligence is still largely relegated to the science fiction shelf.

At the same time, researchers largely agree that AI is likely to begin outperforming humans on most cognitive tasks in this century. Given how disruptive domain-general AI could be, we think it is prudent to begin a conversation about this now, and to investigate whether there are limited areas in which we can predict and shape this technology’s societal impact.

Researchers at MIRI tend to be relatively agnostic about how the state of the art in AI will change over the coming decades, and how many years off smarter-than human AI systems are. 

Machine Intelligence Research Institute

One of GiveWell's top charities for the past several years, AMF provides anti-malarial bednets to people in need. 

From Givewell: 
What do they do? AMF (againstmalaria.com) provides funding for long-lasting insecticide-treated net (LLIN) distributions (for protection against malaria) in developing countries. (More)

Does it work? There is strong evidence that distributing LLINs reduces child mortality and malaria cases. AMF conducts post-distribution surveys of completed distributions to determine whether LLINs have reached their intended destinations and how long they remain in good condition. AMF's post-distribution surveys have generally found positive results but have some methodological limitations. (More)

What do you get for your dollar? We estimate that the cost to purchase and distribute an AMF-funded net is $4.95, or $4.65 excluding in-kind contributions from governments. The numbers of deaths averted and other benefits of distributing LLINs are a function of a number of difficult-to-estimate factors, which we discuss in detail below. (More)

Is there room for more funding? We believe that AMF is likely to be constrained by funding. We estimate that AMF could use up to an additional $37.8 million to support LLIN distributions that will occur between now and late 2023. 

AMF is recommended because of its:

Focus on a program with excellent evidence of effectiveness and cost-effectiveness.
Processes for ensuring that nets reach their intended recipients and monitoring whether they remain in homes and in good condition over the long-term.
Room for more funding – we believe AMF will be able to use additional funds to deliver additional nets.
Transparency – AMF shares significant information about its work with us and we are able to closely follow and understand its work.

The Against Malaria Foundation

Animal Charity Evaluators helps people help the most animals.

Animal Charity Evaluators (ACE) is a 501(c)(3) nonprofit registered in the United States with a globally distributed team dedicated to impactful animal advocacy. Our mission is to find and promote the most effective ways to help animals. We work toward that mission by evaluating charities, sharing our findings, awarding grants to organizations and promising projects, and fundraising for our recommended charities and grantees. Our organization opposes all systems of oppression and recognizes that they are connected and mutually reinforcing. Ultimately, our vision is a world in which no individual is given less than full moral consideration on the basis of any morally irrelevant feature of their identity, including species membership.

ACE is proud to be considered a leader in the effective animal advocacy movement. Our research comparing the different approaches to reducing the suffering of animals has led to rigorously reviewing charities that work to end factory farming and create meaningful change for farmed and wild animals. Through our Recommend Charity Fund, we have raised and distributed $8.1M to our effective recommended charities. Our Movement Grants program has awarded $5.3M to promising animal advocacy projects around the globe. Since we began tracking this metric in 2014, we estimate that ACE has helped to influence nearly $60M within the animal advocacy movement.

Thanks for helping ACE help animals!